Detailed information of TA system TA059172

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2857630..2858186
• Replicon: chromosome
• Accession: NZ_CP013670
• Organism: Xanthomonas oryzae pv. oryzae strain PXO71

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: ATY42_RS13620
• Protein ID: WP_027703932.1
• Coordinates: 2857630..2857920 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: ATY42_RS13625
• Protein ID: WP_011408759.1
• Coordinates: 2857908..2858186 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ATY42_RS13585	2853400..2854491	+	1092	WP_041182166.1	ribonuclease D	-
ATY42_RS13590	2854567..2854904	-	338	Protein_2553	ATP-dependent DNA ligase	-
ATY42_RS27005	2854964..2855170	-	207	Protein_2554	hypothetical protein	-
ATY42_RS24740	2855186..2855362	-	177	Protein_2555	DUF3606 domain-containing protein	-
ATY42_RS13600	2855584..2855985	+	402	WP_011259345.1	H-NS histone family protein	-
ATY42_RS24745	2856310..2856514	-	205	Protein_2557	kfra protein	-
ATY42_RS13610	2856849..2857028	-	180	WP_015463309.1	hypothetical protein	-
ATY42_RS27010	2857172..2857369	-	198	WP_004541336.1	hypothetical protein	-
ATY42_RS13620	2857630..2857920	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ATY42_RS13625	2857908..2858186	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
ATY42_RS24760	2858267..2858699	-	433	Protein_2562	relaxase	-
ATY42_RS24765	2858671..2858871	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
ATY42_RS13630	2859632..2860816	-	1185	WP_011408397.1	IS256 family transposase	-
ATY42_RS13635	2861397..2862362	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
ATY42_RS24770	2862464..2863069	+	606	Protein_2566	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T59172 WP_027703932.1 NZ_CP013670:c2857920-2857630 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T59172 NZ_CP013670:c2857920-2857630 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT59172 WP_011408759.1 NZ_CP013670:c2858186-2857908 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT59172 NZ_CP013670:c2858186-2857908 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2