Detailed information of TA system TA059168

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/PRK09907-MazE
• Location: 2951148..2951725
• Replicon: chromosome
• Accession: NZ_CP013666
• Organism: Xanthomonas oryzae pv. oryzae strain AXO1947

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: AXO1947_RS22010
• Protein ID: WP_196381723.1
• Coordinates: 2951148..2951444 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: A0A411Y3T7
• Locus tag: AXO1947_RS12350
• Protein ID: WP_017154976.1
• Coordinates: 2951483..2951725 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AXO1947_RS12335	2950345..2950346	-	2	WP_107490965.1	IS3 family transposase	-
AXO1947_RS12345	2950661..2951026	-	366	Protein_2463	transposase	-
AXO1947_RS22010	2951148..2951444	-	297	WP_196381723.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
AXO1947_RS12350	2951483..2951725	-	243	WP_017154976.1	hypothetical protein	Antitoxin
AXO1947_RS12355	2951821..2953311	-	1491	WP_033003336.1	site-specific integrase	-
AXO1947_RS12365	2953863..2954879	-	1017	WP_024743446.1	LysR family transcriptional regulator	-
AXO1947_RS12370	2954979..2955563	+	585	WP_024743447.1	NAD(P)H-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (6-95)

Antitoxin

• Antitoxin PemI-like (4-76)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 10706.15 Da
• Isoelectric Point: 8.0458

>T59168 WP_196381723.1 NZ_CP013666:c2951444-2951148 [Xanthomonas oryzae pv. oryzae]
MDDVGGAGHEQRGDRPHLVLSSQGYNDTTSLVVCVPVTTKPKGNPFEVSLNDLNKPSVALTNQVMTADWRSRNAFPRGFA
NKAEMLQVEAKVRALLQL

Nucleotide

• Length: 297 bp

>T59168 NZ_CP013666:c2951444-2951148 [Xanthomonas oryzae pv. oryzae]
TTGGATGATGTGGGTGGGGCCGGTCATGAGCAGCGTGGGGACCGGCCACACTTGGTTCTCAGTTCGCAAGGCTACAACGA
CACAACTAGTCTAGTGGTTTGCGTTCCTGTCACAACTAAACCCAAAGGCAATCCTTTTGAAGTAAGCCTTAATGATTTGA
ACAAGCCAAGTGTTGCTTTAACAAATCAGGTCATGACGGCAGATTGGCGCAGTAGAAATGCTTTTCCCCGAGGGTTTGCT
AATAAAGCTGAAATGCTCCAAGTTGAAGCCAAGGTTCGCGCTTTGCTTCAACTTTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8786.89 Da
• Isoelectric Point: 4.3753

>AT59168 WP_017154976.1 NZ_CP013666:c2951725-2951483 [Xanthomonas oryzae pv. oryzae]
MAVLKMWGNSAAVRIPATYLEESKFSIDEPLVITAEEGRIVIESSKPSYNLADLVAQITPENTHGFAGHSQRVGAEDIEW

Nucleotide

• Length: 243 bp

>AT59168 NZ_CP013666:c2951725-2951483 [Xanthomonas oryzae pv. oryzae]
ATGGCTGTTTTGAAGATGTGGGGGAATAGTGCTGCAGTTCGAATCCCGGCGACCTATCTCGAGGAGTCCAAGTTTTCTAT
TGACGAGCCTCTTGTAATCACTGCGGAGGAAGGTCGCATTGTGATCGAGTCGAGTAAGCCGTCTTATAACCTCGCGGACT
TGGTTGCTCAAATCACTCCAGAAAACACGCACGGCTTTGCTGGGCATTCCCAGAGAGTCGGGGCGGAGGATATTGAATGG
TAA

Structures

Antitoxin

• AlphaFold DB: A0A411Y3T7