Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 463344..463705 Replicon chromosome
Accession NZ_CP013666
Organism Xanthomonas oryzae pv. oryzae strain AXO1947

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag AXO1947_RS01970 Protein ID WP_011257368.1
Coordinates 463571..463705 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag AXO1947_RS01965 Protein ID WP_011407410.1
Coordinates 463344..463496 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AXO1947_RS01945 459588..460271 - 684 WP_024744474.1 dTMP kinase -
AXO1947_RS01950 460787..461329 - 543 WP_024744475.1 GTPase -
AXO1947_RS01955 461326..461991 - 666 WP_024744476.1 hypothetical protein -
AXO1947_RS01960 462313..463236 + 924 WP_053512953.1 arginase -
AXO1947_RS01965 463344..463496 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
AXO1947_RS01970 463571..463705 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
AXO1947_RS01975 463946..464155 + 210 WP_024744478.1 CsbD family protein -
AXO1947_RS01980 464324..465613 + 1290 WP_024744479.1 tryptophan--tRNA ligase -
AXO1947_RS01985 465666..466688 + 1023 WP_165403720.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T59167 WP_011257368.1 NZ_CP013666:463571-463705 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T59167 NZ_CP013666:463571-463705 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT59167 WP_011407410.1 NZ_CP013666:463344-463496 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT59167 NZ_CP013666:463344-463496 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References