Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2252470..2252741 Replicon chromosome
Accession NZ_CP013663
Organism Escherichia coli strain GB089

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2252508..2252611 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2252470..2252741 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO57_RS12705 2249627..2251066 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CO57_RS12710 2251184..2251420 + 237 WP_001295499.1 DUF1480 family protein -
CO57_RS12715 2251525..2251716 + 192 WP_001296140.1 YebW family protein -
CO57_RS12720 2251717..2252373 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2252470..2252741 + 272 - - Antitoxin
- 2252508..2252611 - 104 - - Toxin
CO57_RS12730 2252769..2253110 - 342 WP_000976492.1 YebY family protein -
CO57_RS12735 2253123..2253995 - 873 WP_000879285.1 copper homeostasis membrane protein CopD -
CO57_RS12740 2253999..2254373 - 375 WP_000204699.1 CopC domain-containing protein YobA -
CO57_RS12745 2254512..2254742 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CO57_RS12750 2254844..2255500 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
CO57_RS12755 2255524..2256186 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T59150 NZ_CP013663:c2252611-2252508 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT59150 NZ_CP013663:2252470-2252741 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References