Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2159597..2159868 Replicon chromosome
Accession NZ_CP013662
Organism Escherichia coli strain 08-00022

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2159635..2159738 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2159597..2159868 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CP48_RS12415 2156754..2158193 + 1440 WP_001400472.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CP48_RS12420 2158311..2158547 + 237 WP_001338166.1 DUF1480 family protein -
CP48_RS12425 2158652..2158843 + 192 WP_001338167.1 YebW family protein -
CP48_RS12430 2158844..2159500 - 657 WP_000812733.1 protein-serine/threonine phosphatase -
- 2159597..2159868 + 272 - - Antitoxin
- 2159635..2159738 - 104 - - Toxin
CP48_RS12440 2159896..2160237 - 342 WP_000976472.1 YebY family protein -
CP48_RS12445 2160250..2161122 - 873 WP_000879298.1 copper homeostasis membrane protein CopD -
CP48_RS12450 2161126..2161500 - 375 WP_000255065.1 CopC domain-containing protein YobA -
CP48_RS12455 2161639..2161869 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CP48_RS12460 2161971..2162627 + 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
CP48_RS12465 2162651..2163313 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T59124 NZ_CP013662:c2159738-2159635 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT59124 NZ_CP013662:2159597-2159868 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References