Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2013968..2014450 Replicon chromosome
Accession NZ_CP013661
Organism Planococcus kocurii strain ATCC 43650

Toxin (Protein)


Gene name relE Uniprot ID A0A5B0CN43
Locus tag AUO94_RS09940 Protein ID WP_058384066.1
Coordinates 2013968..2014231 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A5B0CN16
Locus tag AUO94_RS09945 Protein ID WP_058384067.1
Coordinates 2014238..2014450 (-) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AUO94_RS09910 2009233..2010132 + 900 WP_058384060.1 ATP-binding cassette domain-containing protein -
AUO94_RS09915 2010119..2011327 + 1209 WP_058384061.1 ABC transporter permease -
AUO94_RS09920 2011679..2012131 - 453 WP_058384062.1 GNAT family N-acetyltransferase -
AUO94_RS09925 2012150..2012329 - 180 WP_058384063.1 hypothetical protein -
AUO94_RS09930 2012387..2012587 - 201 WP_058384064.1 hypothetical protein -
AUO94_RS17270 2012649..2012789 - 141 WP_156423942.1 hypothetical protein -
AUO94_RS09935 2013030..2013326 + 297 WP_058384065.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
AUO94_RS17275 2013680..2013757 - 78 Protein_1903 AbrB family transcriptional regulator -
AUO94_RS09940 2013968..2014231 - 264 WP_058384066.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AUO94_RS09945 2014238..2014450 - 213 WP_058384067.1 hypothetical protein Antitoxin
AUO94_RS17065 2014687..2015649 - 963 WP_082707526.1 DUF3885 domain-containing protein -
AUO94_RS09955 2015696..2015983 - 288 WP_058384068.1 hypothetical protein -
AUO94_RS17420 2016228..2016701 + 474 WP_058384069.1 hypothetical protein -
AUO94_RS09965 2016761..2017141 - 381 Protein_1909 VOC family protein -
AUO94_RS09970 2017440..2018128 + 689 Protein_1910 copper homeostasis protein CutC -
AUO94_RS09975 2018402..2018911 - 510 WP_058384070.1 MepB family protein -
AUO94_RS17425 2018985..2019235 - 251 Protein_1912 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Protein of unknown function DUF6290

(1-68)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10334.04 Da        Isoelectric Point: 9.6404

>T59113 WP_058384066.1 NZ_CP013661:c2014231-2013968 [Planococcus kocurii]
MYAVHFSDVALKKLKKMDRYQASLLIGWIEKNLKDTDDPRIQGKAFVENHKGKWRYRVGDYRILALIEDEKIIITIIDVG
HRKDIYE

Download         Length: 264 bp

>T59113 NZ_CP013661:c2014231-2013968 [Planococcus kocurii]
ATGTATGCAGTTCATTTCTCAGATGTCGCGTTGAAGAAATTAAAAAAGATGGACCGGTACCAGGCCTCTCTCCTGATTGG
CTGGATTGAAAAGAACTTGAAGGATACCGACGATCCACGAATACAAGGCAAGGCATTTGTTGAAAACCACAAAGGCAAGT
GGCGTTACCGGGTTGGTGATTACCGTATTTTAGCGTTGATCGAAGACGAAAAGATCATTATTACCATTATCGATGTTGGG
CATCGAAAAGATATCTACGAATAA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8039.14 Da        Isoelectric Point: 4.4734

>AT59113 WP_058384067.1 NZ_CP013661:c2014450-2014238 [Planococcus kocurii]
MATISLRVDDRDSKLIRDYAKLKNTSVSDLMRNAIIEKIEDELDVENFDRVLATMETTHSLDDVKKELGL

Download         Length: 213 bp

>AT59113 NZ_CP013661:c2014450-2014238 [Planococcus kocurii]
ATGGCCACTATTTCTTTGCGTGTGGATGACCGCGACAGCAAACTCATCCGCGACTACGCCAAACTGAAAAACACATCTGT
TTCGGATTTGATGCGGAATGCCATCATCGAGAAGATTGAAGATGAACTGGATGTCGAAAACTTTGACCGGGTCCTTGCCA
CTATGGAAACAACCCATTCCTTGGATGACGTCAAAAAAGAATTGGGTTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5B0CN43

Antitoxin

Source ID Structure
AlphaFold DB A0A5B0CN16

References