Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 1239563..1240202 Replicon chromosome
Accession NZ_CP013661
Organism Planococcus kocurii strain ATCC 43650

Toxin (Protein)


Gene name pemK Uniprot ID E7RK71
Locus tag AUO94_RS06085 Protein ID WP_008432415.1
Coordinates 1239563..1239913 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID A0A5B0CU35
Locus tag AUO94_RS06090 Protein ID WP_058386377.1
Coordinates 1239918..1240202 (-) Length 95 a.a.

Genomic Context

AUO94_RS06105AUO94_RS06050AUO94_RS06055AUO94_RS06060AUO94_RS06065AUO94_RS06070AUO94_RS06075AUO94_RS06080AUO94_RS06085AUO94_RS06090AUO94_RS06095AUO94_RS06100AUO94_RS06110AUO94_RS06115
Location: 1241841..1242449 (609 bp)
Type: Others
Protein ID: WP_058386380.1
Location: 1235130..1235912 (783 bp)
Type: Others
Protein ID: WP_058386371.1
Location: 1235890..1236360 (471 bp)
Type: Others
Protein ID: WP_058386372.1
Location: 1236362..1236691 (330 bp)
Type: Others
Protein ID: WP_058386373.1
Location: 1236788..1237789 (1002 bp)
Type: Others
Protein ID: WP_058386374.1
Location: 1237802..1238203 (402 bp)
Type: Others
Protein ID: WP_058386375.1
Location: 1238206..1238571 (366 bp)
Type: Others
Protein ID: WP_177167575.1
Location: 1238568..1239395 (828 bp)
Type: Others
Protein ID: WP_058386376.1
Location: 1239563..1239913 (351 bp)
Type: Toxin
Protein ID: WP_008432415.1
Location: 1239918..1240202 (285 bp)
Type: Antitoxin
Protein ID: WP_058386377.1
Location: 1240246..1241403 (1158 bp)
Type: Others
Protein ID: WP_058386378.1
Location: 1241419..1241772 (354 bp)
Type: Others
Protein ID: WP_058386379.1
Location: 1242493..1244004 (1512 bp)
Type: Others
Protein ID: WP_058386970.1
Location: 1243997..1244476 (480 bp)
Type: Others
Protein ID: WP_058386381.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AUO94_RS060501235130..1235912-783WP_058386371.1RNA polymerase sigma factor SigB-
AUO94_RS060551235890..1236360-471WP_058386372.1anti-sigma B factor RsbW-
AUO94_RS060601236362..1236691-330WP_058386373.1anti-sigma factor antagonist-
AUO94_RS060651236788..1237789-1002WP_058386374.1PP2C family protein-serine/threonine phosphatase-
AUO94_RS060701237802..1238203-402WP_058386375.1anti-sigma regulatory factor-
AUO94_RS060751238206..1238571-366WP_177167575.1STAS domain-containing protein-
AUO94_RS060801238568..1239395-828WP_058386376.1STAS domain-containing protein-
AUO94_RS060851239563..1239913-351WP_008432415.1type II toxin-antitoxin system PemK/MazF family toxinToxin
AUO94_RS060901239918..1240202-285WP_058386377.1hypothetical proteinAntitoxin
AUO94_RS060951240246..1241403-1158WP_058386378.1alanine racemase-
AUO94_RS061001241419..1241772-354WP_058386379.1holo-ACP synthase-
AUO94_RS061051241841..1242449+609WP_058386380.1rhomboid family intramembrane serine protease-
AUO94_RS061101242493..1244004-1512WP_058386970.1PH domain-containing protein-
AUO94_RS061151243997..1244476-480WP_058386381.1PH domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12880.97 Da        Isoelectric Point: 5.8817

>T59112 WP_008432415.1 NZ_CP013661:c1239913-1239563 [Planococcus kocurii]
MIVKRGDVFFAELSPVVGSEQGGTRPVLVIQNDIGNRFSPTVIIAAITAQIQKAKLPTHVEINAKKYGFERDSVILLEQL
RTIDKSRLTDKITQLDDTLMEKVDEALEISVGLVKF

Download         Length: 351 bp

>T59112 NZ_CP013661:c1239913-1239563 [Planococcus kocurii]
TTGATTGTAAAACGCGGAGATGTTTTTTTTGCGGAATTATCGCCAGTCGTCGGGTCTGAGCAGGGTGGGACCCGACCTGT
ACTGGTGATTCAAAACGATATAGGGAATCGTTTTAGTCCCACTGTTATTATTGCAGCAATCACGGCGCAAATTCAAAAAG
CCAAATTACCGACTCATGTAGAAATCAACGCCAAGAAATACGGCTTTGAGCGCGATTCCGTTATTTTGCTAGAACAATTG
CGAACCATTGACAAGTCGCGACTGACCGACAAAATTACGCAGCTTGACGACACTTTGATGGAAAAAGTAGACGAAGCATT
AGAAATCAGCGTAGGTCTTGTTAAATTTTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10764.16 Da        Isoelectric Point: 6.3231

>AT59112 WP_058386377.1 NZ_CP013661:c1240202-1239918 [Planococcus kocurii]
VYEKSKTKEVVVKMPKQFISELTTHSNEHVQESGDYIYVSTSRVTKNLYDSYHIREAMIKGYVEMSQINLSIACECSHAE
YEAEHMTVRLVSGG

Download         Length: 285 bp

>AT59112 NZ_CP013661:c1240202-1239918 [Planococcus kocurii]
GTGTACGAGAAGTCAAAGACAAAAGAAGTGGTTGTGAAAATGCCAAAGCAATTTATTTCAGAGTTGACAACTCATTCAAA
TGAGCATGTCCAAGAAAGTGGAGATTATATTTATGTTTCCACAAGCCGGGTGACAAAAAATCTGTATGACTCATATCATA
TTCGAGAAGCGATGATCAAAGGCTACGTGGAGATGTCTCAAATCAATCTATCGATTGCTTGTGAATGTTCTCACGCTGAG
TATGAAGCGGAGCATATGACTGTCCGACTCGTAAGCGGAGGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1C7DUM1

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A5B0CU35

References