Detailed information of TA system TA059055

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 2357988..2358586
• Replicon: chromosome
• Accession: NZ_CP013630
• Organism: Rhizobium sp. N324

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AMK05_RS11365
• Protein ID: WP_064838542.1
• Coordinates: 2357988..2358281 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A235AWC3
• Locus tag: AMK05_RS11370
• Protein ID: WP_064838543.1
• Coordinates: 2358278..2358586 (-)
• Length: 103 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AMK05_RS11345	2354439..2355578	+	1140	WP_064838538.1	esterase-like activity of phytase family protein	-
AMK05_RS11350	2355694..2356911	+	1218	WP_064838539.1	AI-2E family transporter	-
AMK05_RS11355	2356978..2357436	-	459	WP_064838540.1	GNAT family N-acetyltransferase	-
AMK05_RS11360	2357565..2357975	+	411	WP_064838541.1	hypothetical protein	-
AMK05_RS11365	2357988..2358281	-	294	WP_064838542.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
AMK05_RS11370	2358278..2358586	-	309	WP_064838543.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
AMK05_RS11375	2358695..2359840	-	1146	WP_064838544.1	DUF2336 domain-containing protein	-
AMK05_RS11380	2359947..2360558	-	612	WP_064838545.1	flavin reductase family protein	-
AMK05_RS11385	2360558..2361142	-	585	WP_064838546.1	nitroreductase	-
AMK05_RS11390	2361256..2362356	+	1101	WP_064838547.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (4-53)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11081.75 Da
• Isoelectric Point: 7.1658

>T59055 WP_064838542.1 NZ_CP013630:c2358281-2357988 [Rhizobium sp. N324]
VRLVWARCAVSDRDNIFTYIEIENPRAAVHVDQKIVFAVRRLVEFPESGRPGRIAGTRELVIPGTPYIAAYIVQEDRIRI
LRVLHGAQVWPDDISTE

Nucleotide

• Length: 294 bp

>T59055 NZ_CP013630:c2358281-2357988 [Rhizobium sp. N324]
GTGAGGCTTGTTTGGGCCAGGTGTGCCGTATCCGACCGAGACAATATTTTCACATACATTGAGATCGAGAATCCAAGGGC
GGCAGTCCATGTCGACCAGAAAATCGTTTTTGCTGTTCGCCGTCTCGTCGAATTTCCGGAAAGCGGAAGACCGGGAAGGA
TCGCAGGCACGCGGGAGTTGGTCATCCCAGGCACGCCCTATATCGCCGCATACATCGTGCAGGAAGACCGAATTCGGATC
CTTCGCGTCCTCCACGGTGCCCAGGTTTGGCCCGACGACATTTCAACTGAATGA

Antitoxin

Protein

• Length: 103 a.a.
• Molecular weight: 11036.40 Da
• Isoelectric Point: 4.5423

>AT59055 WP_064838543.1 NZ_CP013630:c2358586-2358278 [Rhizobium sp. N324]
MASNALVQTRIDAAVKDRATAVLEDMGLTVSDVVRILLTRTANEGALPLELISNSDAYDAWFRGKVLEALNDTRADVDDA
DVEASFEKRRAAALRKSKAAES

Nucleotide

• Length: 309 bp

>AT59055 NZ_CP013630:c2358586-2358278 [Rhizobium sp. N324]
ATGGCGTCAAACGCGCTCGTACAAACTCGCATAGATGCTGCCGTCAAGGATCGCGCTACGGCTGTTTTGGAAGATATGGG
TCTGACAGTCTCGGATGTCGTGCGCATTTTATTGACCCGCACGGCGAACGAGGGGGCTCTGCCGCTCGAACTTATCAGCA
ACAGCGACGCTTATGACGCATGGTTTCGTGGAAAGGTCCTTGAAGCTCTCAATGACACGCGAGCCGATGTCGATGATGCC
GATGTCGAGGCGAGCTTCGAGAAGAGGCGCGCGGCCGCATTGCGGAAGAGCAAGGCCGCTGAATCGTGA

Structures

Antitoxin

• AlphaFold DB: A0A235AWC3