Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 337961..338658 Replicon plasmid pRspN731e
Accession NZ_CP013606
Organism Rhizobium sp. N731

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AMK02_RS29020 Protein ID WP_064808526.1
Coordinates 337961..338407 (-) Length 149 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AMK02_RS29025 Protein ID WP_064808528.1
Coordinates 338404..338658 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMK02_RS29000 333763..335055 + 1293 WP_064808514.1 L-rhamnose catabolism isomerase -
AMK02_RS29005 335123..335581 - 459 WP_064808516.1 carboxymuconolactone decarboxylase family protein -
AMK02_RS29010 335690..336559 + 870 WP_064808518.1 sigma-70 family RNA polymerase sigma factor -
AMK02_RS29015 336730..337938 + 1209 WP_064808853.1 amidohydrolase/deacetylase family metallohydrolase -
AMK02_RS29020 337961..338407 - 447 WP_064808526.1 type II toxin-antitoxin system VapC family toxin Toxin
AMK02_RS29025 338404..338658 - 255 WP_064808528.1 hypothetical protein Antitoxin
AMK02_RS29030 338746..339585 - 840 WP_064808530.1 IclR family transcriptional regulator -
AMK02_RS29035 339739..340161 - 423 WP_064808532.1 type II toxin-antitoxin system VapC family toxin -
AMK02_RS29040 340161..340409 - 249 WP_064808552.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
AMK02_RS29045 340524..341381 + 858 WP_064808855.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..506687 506687


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 149 a.a.        Molecular weight: 15799.01 Da        Isoelectric Point: 4.8781

>T59014 WP_064808526.1 NZ_CP013606:c338407-337961 [Rhizobium sp. N731]
MIVLDTNVLCEAMKPAPNPAVRSWLNEQVAETLYLSSVTLAELLFGIGTLPDGRRKAALSETLGGVLDLFGDRILPFDVG
AARHYADLAVRARADGKGFPTPNGYIAAIAASKGFMIATRDVSPFEAAGLIVINPWNHRSSEASQEDS

Download         Length: 447 bp

>T59014 NZ_CP013606:c338407-337961 [Rhizobium sp. N731]
ATGATCGTCCTGGATACGAACGTCCTTTGCGAGGCGATGAAACCGGCTCCTAATCCGGCAGTGCGTTCGTGGCTGAACGA
GCAGGTCGCTGAAACCTTGTATCTATCGAGTGTGACCTTGGCCGAACTGCTGTTTGGCATCGGTACGTTGCCGGACGGTC
GGCGCAAAGCGGCTCTGAGCGAAACGCTCGGCGGCGTGCTCGACCTGTTTGGCGATCGGATATTGCCGTTCGACGTCGGA
GCGGCCCGGCATTATGCCGACCTTGCCGTCAGAGCGCGAGCGGACGGCAAAGGCTTCCCAACGCCCAATGGATATATCGC
CGCCATTGCCGCTTCGAAGGGCTTTATGATCGCAACGCGCGACGTGAGCCCGTTTGAGGCGGCAGGACTGATTGTCATAA
ATCCCTGGAACCATCGATCATCTGAGGCCTCTCAGGAGGATTCATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9385.62 Da        Isoelectric Point: 5.1358

>AT59014 WP_064808528.1 NZ_CP013606:c338658-338404 [Rhizobium sp. N731]
MAVLTVRNVPDEVHRALRVRAAMHGRSTEAEVREILESAVKPEQRIRMGDALAALSRQQGLTDDDFAVFDQVRDSAPAEP
LKFE

Download         Length: 255 bp

>AT59014 NZ_CP013606:c338658-338404 [Rhizobium sp. N731]
ATGGCCGTTCTGACAGTTCGAAATGTGCCCGATGAAGTGCATCGGGCATTGCGCGTGCGGGCGGCCATGCACGGCCGCAG
CACCGAGGCGGAAGTTCGTGAAATCCTGGAAAGTGCGGTGAAGCCGGAGCAACGCATTCGTATGGGGGATGCCTTGGCGG
CGCTCAGTCGGCAGCAGGGGCTGACCGATGATGATTTCGCAGTGTTCGATCAGGTACGCGACAGCGCGCCGGCGGAGCCG
TTGAAGTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References