Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 126080..126816 Replicon plasmid pRphaN161c
Accession NZ_CP013588
Organism Rhizobium phaseoli strain N161

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag AMC78_RS25835 Protein ID WP_064836877.1
Coordinates 126322..126816 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag AMC78_RS25830 Protein ID WP_064819986.1
Coordinates 126080..126325 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMC78_RS25815 122889..123272 - 384 WP_064836873.1 type II toxin-antitoxin system VapC family toxin -
AMC78_RS25820 123269..123469 - 201 WP_064836874.1 type II toxin-antitoxin system VapB family antitoxin -
AMC78_RS25825 123805..125922 + 2118 WP_064836876.1 carboxy terminal-processing peptidase -
AMC78_RS25830 126080..126325 + 246 WP_064819986.1 DUF1778 domain-containing protein Antitoxin
AMC78_RS25835 126322..126816 + 495 WP_064836877.1 GNAT family N-acetyltransferase Toxin
AMC78_RS25840 126946..127842 + 897 WP_064836878.1 GGDEF domain-containing protein -
AMC78_RS25845 127855..128220 - 366 WP_064836879.1 hypothetical protein -
AMC78_RS25850 128245..128715 - 471 WP_064836881.1 hypothetical protein -
AMC78_RS25855 128735..129955 - 1221 WP_064836882.1 hypothetical protein -
AMC78_RS25860 129998..130762 - 765 WP_064836883.1 TfuA-like protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..407297 407297


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(27-142)

Antitoxin

Vibrio phage ICP1, Orf50

(1-73)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17783.44 Da        Isoelectric Point: 9.0589

>T58990 WP_064836877.1 NZ_CP013588:126322-126816 [Rhizobium phaseoli]
VTLSRPAPLADHHELAEFSSGVAELDEWLRRRARANQASGASRTFVVCEGNRVIAYYALASGVVRQPEAPGRFRRNMPDP
IPVAVLGRLAIDQSHQGRGIGRALVRDAGLRLVNAAEILGIRGLLVHAISDDARAFYEAVGFLPLPSDPMMLMVGLHDLN
SALR

Download         Length: 495 bp

>T58990 NZ_CP013588:126322-126816 [Rhizobium phaseoli]
GTGACTCTCAGCCGGCCGGCGCCTTTGGCCGATCATCACGAACTGGCCGAATTCAGCTCCGGCGTGGCTGAACTGGACGA
ATGGCTGCGTCGCCGCGCCCGCGCCAATCAGGCAAGCGGCGCGTCGCGCACCTTCGTCGTGTGCGAGGGAAACCGGGTCA
TCGCCTATTATGCGCTCGCCTCTGGAGTGGTGCGGCAGCCGGAAGCGCCCGGCCGTTTTCGGCGGAACATGCCCGACCCT
ATCCCGGTTGCCGTGCTAGGCCGCCTCGCCATCGATCAATCCCACCAGGGGCGCGGTATCGGCAGGGCATTGGTGCGCGA
TGCGGGCCTGCGCCTGGTCAACGCCGCAGAAATCCTCGGAATTCGCGGTCTGCTGGTGCATGCGATTTCCGACGACGCGC
GCGCCTTCTATGAGGCGGTCGGCTTCCTGCCGTTGCCATCCGATCCCATGATGCTGATGGTCGGGTTGCATGATCTCAAC
AGCGCGCTGCGGTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9278.63 Da        Isoelectric Point: 6.3604

>AT58990 WP_064819986.1 NZ_CP013588:126080-126325 [Rhizobium phaseoli]
MRIKPATRNLIDRAAELLGKTRTDFMLEASERRAEEVLLDRTVFTVSPEIYAEYLARLDAPAEPNARLKRTMSTKAPWDE
A

Download         Length: 246 bp

>AT58990 NZ_CP013588:126080-126325 [Rhizobium phaseoli]
ATGCGGATCAAGCCTGCGACCCGCAATTTGATCGACCGTGCCGCCGAACTGCTTGGCAAGACGCGCACGGATTTCATGCT
GGAGGCTTCGGAGCGCCGGGCTGAGGAAGTGCTGCTCGACCGGACGGTATTCACGGTCAGCCCCGAGATCTATGCCGAAT
ATCTTGCCCGCCTGGATGCGCCGGCTGAGCCCAATGCGCGTCTGAAACGGACGATGTCGACCAAAGCGCCATGGGATGAA
GCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References