Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 563258..563793 Replicon plasmid pRphaN831d
Accession NZ_CP013567
Organism Rhizobium phaseoli strain N831

Toxin (Protein)


Gene name relE Uniprot ID A0A0M3GDG7
Locus tag AMC82_RS29195 Protein ID WP_016735850.1
Coordinates 563258..563533 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID F2AEZ7
Locus tag AMC82_RS29200 Protein ID WP_004677393.1
Coordinates 563533..563793 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMC82_RS29175 558449..559375 - 927 WP_064824299.1 sugar ABC transporter permease -
AMC82_RS29180 559443..560663 - 1221 WP_037145720.1 sugar ABC transporter substrate-binding protein -
AMC82_RS29185 560713..562035 - 1323 WP_012490003.1 alpha-L-fucosidase -
AMC82_RS29190 562244..563251 + 1008 WP_004677397.1 LacI family transcriptional regulator -
AMC82_RS29195 563258..563533 - 276 WP_016735850.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AMC82_RS29200 563533..563793 - 261 WP_004677393.1 ribbon-helix-helix domain-containing protein Antitoxin
AMC82_RS29205 564093..564821 + 729 WP_004677391.1 FadR family transcriptional regulator -
AMC82_RS29210 565112..566125 + 1014 WP_016735851.1 ABC transporter substrate-binding protein -
AMC82_RS29215 566221..567039 + 819 WP_004677388.1 ABC transporter ATP-binding protein -
AMC82_RS29220 567051..567932 + 882 WP_016735853.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd 1..1165895 1165895


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10816.41 Da        Isoelectric Point: 9.5543

>T58955 WP_016735850.1 NZ_CP013567:c563533-563258 [Rhizobium phaseoli]
MEIKWTSKAVSDIARLYDFLSPVDRRAAARTVQALAAAPARLIEQPRLGERLEEFDPQEVRRILVGRYEMRYEIQQSTIY
VLRLWHTREDR

Download         Length: 276 bp

>T58955 NZ_CP013567:c563533-563258 [Rhizobium phaseoli]
ATGGAAATCAAGTGGACGAGCAAAGCTGTCTCCGACATCGCTCGCTTATACGACTTTCTCTCCCCGGTCGACCGGCGAGC
TGCGGCCCGAACCGTGCAGGCGCTGGCGGCAGCCCCCGCTCGTCTAATTGAGCAGCCACGTCTCGGCGAGCGGCTCGAAG
AGTTCGATCCTCAGGAGGTCCGCCGCATTCTCGTTGGCCGTTATGAGATGCGTTATGAAATCCAGCAGTCGACAATCTAT
GTATTGCGGCTTTGGCATACGCGCGAGGATCGGTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9686.93 Da        Isoelectric Point: 4.6135

>AT58955 WP_004677393.1 NZ_CP013567:c563793-563533 [Rhizobium phaseoli]
METKVLTAHVPLPLAQKVDQLASRLERSRGWIVKQALTAWIDQEEERRRLTLEALADVDSGNVVDHQSVQAWADSLDGDE
PISLLR

Download         Length: 261 bp

>AT58955 NZ_CP013567:c563793-563533 [Rhizobium phaseoli]
ATGGAGACCAAAGTTCTCACGGCTCATGTTCCATTGCCGCTTGCGCAGAAGGTCGATCAGCTTGCATCGCGCCTTGAGCG
TTCGCGCGGCTGGATCGTCAAGCAAGCCCTGACTGCATGGATCGACCAGGAAGAGGAGCGTCGGCGTTTGACGCTTGAGG
CGTTAGCCGATGTGGATAGCGGCAATGTTGTCGATCACCAGTCTGTTCAAGCCTGGGCCGATAGTCTTGACGGTGACGAG
CCGATTTCGTTGCTCCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0M3GDG7

Antitoxin

Source ID Structure
AlphaFold DB A0A2U3CQR5

References