Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 130061..130641 Replicon plasmid pRphaN841c
Accession NZ_CP013560
Organism Rhizobium phaseoli strain N841

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AMC83_RS23875 Protein ID WP_064832109.1
Coordinates 130061..130444 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AMC83_RS23880 Protein ID WP_064832110.1
Coordinates 130441..130641 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMC83_RS23860 126388..127113 - 726 WP_064832107.1 DUF2726 domain-containing protein -
AMC83_RS33270 127543..127809 + 267 WP_081278599.1 hypothetical protein -
AMC83_RS23870 128020..129981 + 1962 WP_064832227.1 elongation factor G -
AMC83_RS23875 130061..130444 - 384 WP_064832109.1 type II toxin-antitoxin system VapC family toxin Toxin
AMC83_RS23880 130441..130641 - 201 WP_064832110.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
AMC83_RS23885 130978..133095 + 2118 WP_064832111.1 carboxy terminal-processing peptidase -
AMC83_RS23890 133248..133493 + 246 WP_064832228.1 DUF1778 domain-containing protein -
AMC83_RS23895 133490..133984 + 495 WP_064832229.1 GNAT family N-acetyltransferase -
AMC83_RS23900 134114..135010 + 897 WP_064832112.1 GGDEF domain-containing protein -
AMC83_RS23905 135040..135384 - 345 WP_064832113.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..407882 407882


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14169.22 Da        Isoelectric Point: 6.8445

>T58946 WP_064832109.1 NZ_CP013560:c130444-130061 [Rhizobium phaseoli]
VILADTSIWIDHFRHADSELRRIIEDDRLLCHPAVIGELALGSLRDRSNVIAFLAAQRQAFVATHDEVMMMIDRHAVFSM
GIGYTDAHLIASVLLDQRAALWTRDKRLRAAAEKAGASLHTPDNARS

Download         Length: 384 bp

>T58946 NZ_CP013560:c130444-130061 [Rhizobium phaseoli]
GTGATACTTGCCGACACTTCCATCTGGATCGATCATTTCCGGCATGCCGATTCAGAGCTGCGCAGGATTATCGAGGACGA
TCGTCTCTTATGCCATCCAGCCGTGATCGGAGAGCTCGCACTTGGCAGCCTTCGGGATCGCAGTAACGTGATAGCTTTCC
TGGCGGCCCAGCGCCAAGCGTTCGTCGCGACGCACGACGAAGTCATGATGATGATCGATCGCCACGCCGTTTTCAGCATG
GGCATCGGCTACACAGATGCCCATTTGATCGCTTCGGTTCTACTCGATCAGCGAGCCGCCTTATGGACGAGAGACAAGCG
TCTGCGGGCAGCGGCCGAAAAGGCGGGGGCTTCCCTTCACACGCCCGACAATGCGCGAAGCTAA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7140.23 Da        Isoelectric Point: 11.3760

>AT58946 WP_064832110.1 NZ_CP013560:c130641-130441 [Rhizobium phaseoli]
MRSTINLDDTLMERARSLTGTKETASLVRQALETLVRVESGKRLIALGGTMPDAEAAPRRRSAAAK

Download         Length: 201 bp

>AT58946 NZ_CP013560:c130641-130441 [Rhizobium phaseoli]
ATGCGATCGACTATCAATCTCGACGACACCCTCATGGAAAGGGCGAGGTCCCTAACCGGCACGAAAGAAACCGCCAGTCT
GGTCCGCCAGGCGTTGGAAACGCTTGTTCGTGTGGAGTCGGGAAAACGCCTCATCGCGCTGGGCGGAACTATGCCGGATG
CGGAGGCGGCTCCGCGCCGCCGGAGCGCAGCCGCCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References