Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 306333..306889 Replicon plasmid pRphaR630a
Accession NZ_CP013538
Organism Rhizobium phaseoli strain R630

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AMC87_RS22660 Protein ID WP_064829160.1
Coordinates 306333..306623 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AMC87_RS22665 Protein ID WP_064829161.1
Coordinates 306611..306889 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMC87_RS22630 301402..302169 - 768 WP_064829154.1 LamB/YcsF family protein -
AMC87_RS22635 302191..303186 - 996 WP_064829155.1 biotin-dependent carboxyltransferase family protein -
AMC87_RS22640 303183..303890 - 708 WP_064829156.1 5-oxoprolinase subunit PxpB -
AMC87_RS22645 303887..304312 - 426 WP_064829157.1 hypothetical protein -
AMC87_RS22650 304309..305703 - 1395 WP_064829158.1 acetyl-CoA carboxylase biotin carboxylase subunit -
AMC87_RS22655 305703..306134 - 432 WP_064829159.1 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit -
AMC87_RS22660 306333..306623 - 291 WP_064829160.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AMC87_RS22665 306611..306889 - 279 WP_064829161.1 CopG family ribbon-helix-helix protein Antitoxin
AMC87_RS22670 306985..308055 - 1071 WP_064829162.1 LacI family transcriptional regulator -
AMC87_RS22675 308277..309230 + 954 WP_064829163.1 sugar phosphate isomerase/epimerase -
AMC87_RS22680 309289..310521 + 1233 WP_037146692.1 ABC transporter substrate-binding protein -
AMC87_RS22685 310622..311509 + 888 WP_064829164.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..344843 344843


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10955.74 Da        Isoelectric Point: 10.2737

>T58910 WP_064829160.1 NZ_CP013538:c306623-306333 [Rhizobium phaseoli]
MPQVIFSPAAIRDLKRLREFLRPKNPSVAKRAGETILKGVSLLGTHPHMGRLIENLPEQYREWLIDFGESGYVARYRVDG
DILTILAVRHQKEAGF

Download         Length: 291 bp

>T58910 NZ_CP013538:c306623-306333 [Rhizobium phaseoli]
ATGCCGCAAGTAATCTTCTCTCCGGCCGCAATCCGCGACCTCAAGCGGCTGCGGGAGTTCCTGCGGCCGAAAAACCCGTC
GGTCGCCAAGCGGGCAGGCGAAACCATTCTCAAAGGCGTGAGCCTCCTCGGCACGCATCCCCATATGGGACGCCTCATCG
AAAACTTGCCCGAGCAATATCGCGAATGGCTCATCGATTTCGGAGAGAGCGGATACGTCGCGCGTTATCGTGTGGATGGC
GACATTTTGACGATCCTCGCCGTGCGGCACCAGAAGGAAGCAGGGTTCTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10748.98 Da        Isoelectric Point: 4.9783

>AT58910 WP_064829161.1 NZ_CP013538:c306889-306611 [Rhizobium phaseoli]
MTSPTSLKLDDELKGRVQQLAEARRRSSHWIMREAIAQYVEREEKRETLRQETLDAWKEFEATGLHVTGVEVEKWLSTWG
TDDESSAPECRK

Download         Length: 279 bp

>AT58910 NZ_CP013538:c306889-306611 [Rhizobium phaseoli]
ATGACATCGCCGACCTCGCTCAAGCTCGATGACGAGCTAAAGGGCCGCGTTCAACAATTGGCAGAGGCGCGCCGCCGTTC
GTCCCACTGGATCATGCGTGAAGCCATCGCGCAATATGTCGAGCGCGAGGAGAAGCGCGAGACGCTGCGGCAGGAGACGC
TTGACGCCTGGAAGGAATTTGAAGCGACGGGACTGCACGTCACCGGCGTCGAGGTCGAAAAGTGGCTTTCGACCTGGGGA
ACTGACGACGAGTCGTCCGCCCCCGAATGCCGCAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References