Detailed information of TA system TA058910

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 306333..306889
• Replicon: plasmid pRphaR630a
• Accession: NZ_CP013538
• Organism: Rhizobium phaseoli strain R630

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: AMC87_RS22660
• Protein ID: WP_064829160.1
• Coordinates: 306333..306623 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: AMC87_RS22665
• Protein ID: WP_064829161.1
• Coordinates: 306611..306889 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AMC87_RS22630	301402..302169	-	768	WP_064829154.1	LamB/YcsF family protein	-
AMC87_RS22635	302191..303186	-	996	WP_064829155.1	biotin-dependent carboxyltransferase family protein	-
AMC87_RS22640	303183..303890	-	708	WP_064829156.1	5-oxoprolinase subunit PxpB	-
AMC87_RS22645	303887..304312	-	426	WP_064829157.1	hypothetical protein	-
AMC87_RS22650	304309..305703	-	1395	WP_064829158.1	acetyl-CoA carboxylase biotin carboxylase subunit	-
AMC87_RS22655	305703..306134	-	432	WP_064829159.1	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit	-
AMC87_RS22660	306333..306623	-	291	WP_064829160.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AMC87_RS22665	306611..306889	-	279	WP_064829161.1	CopG family ribbon-helix-helix protein	Antitoxin
AMC87_RS22670	306985..308055	-	1071	WP_064829162.1	LacI family transcriptional regulator	-
AMC87_RS22675	308277..309230	+	954	WP_064829163.1	sugar phosphate isomerase/epimerase	-
AMC87_RS22680	309289..310521	+	1233	WP_037146692.1	ABC transporter substrate-binding protein	-
AMC87_RS22685	310622..311509	+	888	WP_064829164.1	sugar ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..344843	344843

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10955.74 Da
• Isoelectric Point: 10.2737

>T58910 WP_064829160.1 NZ_CP013538:c306623-306333 [Rhizobium phaseoli]
MPQVIFSPAAIRDLKRLREFLRPKNPSVAKRAGETILKGVSLLGTHPHMGRLIENLPEQYREWLIDFGESGYVARYRVDG
DILTILAVRHQKEAGF

Nucleotide

• Length: 291 bp

>T58910 NZ_CP013538:c306623-306333 [Rhizobium phaseoli]
ATGCCGCAAGTAATCTTCTCTCCGGCCGCAATCCGCGACCTCAAGCGGCTGCGGGAGTTCCTGCGGCCGAAAAACCCGTC
GGTCGCCAAGCGGGCAGGCGAAACCATTCTCAAAGGCGTGAGCCTCCTCGGCACGCATCCCCATATGGGACGCCTCATCG
AAAACTTGCCCGAGCAATATCGCGAATGGCTCATCGATTTCGGAGAGAGCGGATACGTCGCGCGTTATCGTGTGGATGGC
GACATTTTGACGATCCTCGCCGTGCGGCACCAGAAGGAAGCAGGGTTCTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10748.98 Da
• Isoelectric Point: 4.9783

>AT58910 WP_064829161.1 NZ_CP013538:c306889-306611 [Rhizobium phaseoli]
MTSPTSLKLDDELKGRVQQLAEARRRSSHWIMREAIAQYVEREEKRETLRQETLDAWKEFEATGLHVTGVEVEKWLSTWG
TDDESSAPECRK

Nucleotide

• Length: 279 bp

>AT58910 NZ_CP013538:c306889-306611 [Rhizobium phaseoli]
ATGACATCGCCGACCTCGCTCAAGCTCGATGACGAGCTAAAGGGCCGCGTTCAACAATTGGCAGAGGCGCGCCGCCGTTC
GTCCCACTGGATCATGCGTGAAGCCATCGCGCAATATGTCGAGCGCGAGGAGAAGCGCGAGACGCTGCGGCAGGAGACGC
TTGACGCCTGGAAGGAATTTGAAGCGACGGGACTGCACGTCACCGGCGTCGAGGTCGAAAAGTGGCTTTCGACCTGGGGA
ACTGACGACGAGTCGTCCGCCCCCGAATGCCGCAAGTAA