Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 391699..392330 Replicon chromosome
Accession NZ_CP013527
Organism Rhizobium phaseoli strain R723

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AMC89_RS01895 Protein ID WP_064817295.1
Coordinates 391699..392091 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AMC89_RS01900 Protein ID WP_037115304.1
Coordinates 392088..392330 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMC89_RS01875 387076..388284 - 1209 WP_064817293.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
AMC89_RS01880 388554..389318 - 765 WP_064817294.1 SDR family oxidoreductase -
AMC89_RS01885 389444..390370 + 927 WP_004673976.1 LysR family transcriptional regulator -
AMC89_RS01890 390375..391613 + 1239 WP_064819318.1 MFS transporter -
AMC89_RS31975 391610..391693 + 84 Protein_368 VOC family protein -
AMC89_RS01895 391699..392091 - 393 WP_064817295.1 type II toxin-antitoxin system VapC family toxin Toxin
AMC89_RS01900 392088..392330 - 243 WP_037115304.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
AMC89_RS01905 392384..394045 - 1662 WP_064817296.1 urocanate hydratase -
AMC89_RS01910 394115..394444 - 330 WP_064817297.1 TfoX/Sxy family protein -
AMC89_RS01915 394448..395545 - 1098 WP_064817298.1 DUF917 domain-containing protein -
AMC89_RS01920 395526..396806 - 1281 WP_064817299.1 Zn-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

SpoVT-AbrB domain

(7-44)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14795.02 Da        Isoelectric Point: 7.3181

>T58889 WP_064817295.1 NZ_CP013527:c392091-391699 [Rhizobium phaseoli]
MKYLLDANAVIALMKGNERVIAELRRHRPQDFAVPAIVAHELFYGAYKSLRTDENLARIEALQFTILEFDRNDARKAGEI
RATLHASGTPIGPYDVLIAGQAAARDLILITRNLRKFERVTFLQIEDWES

Download         Length: 393 bp

>T58889 NZ_CP013527:c392091-391699 [Rhizobium phaseoli]
ATGAAGTACTTGCTCGATGCGAATGCCGTCATTGCCCTTATGAAGGGCAACGAACGCGTAATCGCCGAACTGCGCAGACA
TAGGCCGCAGGATTTTGCCGTGCCAGCAATCGTTGCGCATGAATTGTTCTATGGCGCGTATAAAAGCCTTCGCACCGACG
AGAACCTGGCGCGAATCGAGGCGCTACAATTCACCATCCTGGAATTCGACCGGAACGACGCGCGTAAAGCCGGGGAAATC
CGCGCGACACTACATGCATCTGGAACGCCGATCGGCCCCTATGACGTTCTGATTGCCGGGCAAGCCGCCGCACGCGATCT
CATCCTGATTACCCGCAATCTGCGAAAATTCGAACGTGTGACGTTTTTACAGATCGAGGATTGGGAGAGCTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9212.30 Da        Isoelectric Point: 4.2463

>AT58889 WP_037115304.1 NZ_CP013527:c392330-392088 [Rhizobium phaseoli]
METAKIFWSGRSQAVRLPKEFRFDGDTVAIRRQGRAIILEPMSDDWEWLADVTGPVDPDFATAAEEQPAQQERPELDFFK

Download         Length: 243 bp

>AT58889 NZ_CP013527:c392330-392088 [Rhizobium phaseoli]
ATGGAAACAGCAAAAATCTTCTGGTCAGGGCGTTCCCAAGCCGTTCGGCTGCCCAAGGAATTCCGCTTCGATGGCGATAC
CGTCGCCATTCGACGGCAGGGGCGCGCGATCATTCTTGAGCCGATGTCCGATGATTGGGAATGGCTTGCCGATGTGACCG
GTCCTGTTGATCCCGACTTCGCGACGGCAGCGGAGGAGCAACCTGCTCAGCAGGAGCGACCCGAGCTCGACTTCTTCAAA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References