Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 130634..131370 Replicon plasmid pRphaR744c
Accession NZ_CP013525
Organism Rhizobium phaseoli strain R744

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag AMC90_RS24695 Protein ID WP_064844261.1
Coordinates 130876..131370 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag AMC90_RS24690 Protein ID WP_064819986.1
Coordinates 130634..130879 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMC90_RS24675 127441..127824 - 384 WP_064844257.1 type II toxin-antitoxin system VapC family toxin -
AMC90_RS24680 127821..128021 - 201 WP_016736583.1 type II toxin-antitoxin system VapB family antitoxin -
AMC90_RS24685 128359..130476 + 2118 WP_064844259.1 carboxy terminal-processing peptidase -
AMC90_RS24690 130634..130879 + 246 WP_064819986.1 DUF1778 domain-containing protein Antitoxin
AMC90_RS24695 130876..131370 + 495 WP_064844261.1 GNAT family N-acetyltransferase Toxin
AMC90_RS24700 131500..132396 + 897 WP_064844263.1 GGDEF domain-containing protein -
AMC90_RS24705 132506..132775 - 270 WP_081284282.1 hypothetical protein -
AMC90_RS24710 132802..133278 - 477 WP_064844265.1 hypothetical protein -
AMC90_RS24715 133298..134518 - 1221 WP_064844267.1 hypothetical protein -
AMC90_RS24720 134561..135328 - 768 WP_064844269.1 TfuA-like protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..407814 407814


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-142)

Antitoxin

Vibrio phage ICP1, Orf50

(1-73)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17735.33 Da        Isoelectric Point: 8.5404

>T58885 WP_064844261.1 NZ_CP013525:130876-131370 [Rhizobium phaseoli]
VTLSRPAPLADHHELAEFSSGVAELDEWLCRRARANQASGASRTFVVCEGNRVIAYYALASGAVRQPEAPGRFRRNMPDP
IPVAVLGRLAIDQSHQGRGIGRALVRDAGLRLVNAAEILGIRGLLVHAISDDARAFYEAVGFLPSPSDRMMLMVGLHDLN
SALR

Download         Length: 495 bp

>T58885 NZ_CP013525:130876-131370 [Rhizobium phaseoli]
GTGACTCTCAGCCGGCCGGCGCCTTTGGCCGATCATCACGAACTGGCCGAATTCAGTTCCGGCGTGGCTGAACTGGACGA
ATGGCTTTGTCGCCGCGCCCGCGCCAATCAGGCAAGCGGCGCGTCGCGCACCTTCGTCGTGTGCGAGGGAAACCGGGTCA
TCGCCTATTATGCGCTCGCCTCTGGAGCGGTGCGGCAGCCGGAAGCGCCCGGCCGTTTTCGGCGGAACATGCCCGACCCT
ATCCCGGTTGCCGTGCTTGGCCGCCTCGCCATCGATCAATCCCACCAGGGGCGCGGTATCGGCAGGGCATTGGTGCGCGA
TGCGGGCCTGCGCCTGGTCAACGCCGCAGAAATTCTCGGAATTCGCGGTCTGCTGGTGCATGCGATTTCCGACGACGCGC
GCGCCTTCTATGAGGCGGTCGGCTTCCTGCCGTCGCCATCCGATCGCATGATGCTGATGGTCGGGTTGCATGATCTCAAC
AGCGCGCTACGGTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9278.63 Da        Isoelectric Point: 6.3604

>AT58885 WP_064819986.1 NZ_CP013525:130634-130879 [Rhizobium phaseoli]
MRIKPATRNLIDRAAELLGKTRTDFMLEASERRAEEVLLDRTVFTVSPEIYAEYLARLDAPAEPNARLKRTMSTKAPWDE
A

Download         Length: 246 bp

>AT58885 NZ_CP013525:130634-130879 [Rhizobium phaseoli]
ATGCGGATCAAGCCTGCGACCCGCAATTTGATCGACCGTGCCGCCGAACTGCTTGGCAAGACGCGCACGGATTTCATGCT
GGAGGCTTCGGAGCGCCGGGCTGAGGAAGTGCTGCTCGACCGGACGGTATTCACGGTCAGCCCCGAGATCTATGCCGAAT
ATCTTGCCCGCCTGGATGCGCCGGCTGAGCCCAATGCGCGTCTGAAACGGACGATGTCGACCAAAGCGCCATGGGATGAA
GCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References