58838

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 42191..43533 Replicon plasmid pMBL287
Accession NZ_CP013487
Organism Vibrio alginolyticus strain ATCC 33787

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag AT730_RS24675 Protein ID WP_172797336.1
Coordinates 42191..43126 (-) Length 312 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag AT730_RS24680 Protein ID WP_064369853.1
Coordinates 43129..43533 (-) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AT730_RS24660 37760..38644 - 885 WP_064369850.1 ATP-binding protein -
AT730_RS24665 38647..40488 - 1842 WP_064369851.1 AAA family ATPase -
AT730_RS24670 41031..41921 - 891 WP_081048968.1 IS110 family transposase -
AT730_RS24675 42191..43126 - 936 WP_172797336.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
AT730_RS24680 43129..43533 - 405 WP_064369853.1 hypothetical protein Antitoxin
AT730_RS27700 44008..44178 + 171 WP_155604293.1 hypothetical protein -
AT730_RS24690 45023..46063 - 1041 WP_064369855.1 IS481 family transposase -
AT730_RS24695 46312..47115 - 804 WP_064369856.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - vipA/mglA 1..286750 286750
- inside IScluster/Tn - - 41031..46063 5032


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-300)

Antitoxin

Protein of unknown function DUF6088

(8-130)


Sequences

Toxin        


Download         Length: 312 a.a.        Molecular weight: 35802.75 Da        Isoelectric Point: 5.2949

>T58838 WP_172797336.1 NZ_CP013487:c43126-42191 [Vibrio alginolyticus]
IPKLKKQFLEVSDALELGNPSITEKDYWVVSLLAMLESVESEHHQLVFSGGTALAKSNIKILRMSEDVDIKLIPTQEFLD
KGTGAKRKARKALVEHLITRLADHTYLNYSGKTVRDSYRYVEIEIEYPQQYHQAPCLRPYIKLEFIETIELQGVEPRSIS
SLVAQSYNQPAEVSTMSCISIDSTLVEKVLSMLRRTMSVKRDPQRKDDETLVRHIYDVHCISAEHTIDMGVLKPMFDTVL
EEDRARYGNQHHEFVDDPRNELKLGLEELESNEEFRKRFDAFVAPMVYNTEPHDFDTCFASFKGISEQLIS

Download         Length: 936 bp

>T58838 NZ_CP013487:c43126-42191 [Vibrio alginolyticus]
ATACCAAAACTAAAAAAACAATTTCTTGAAGTATCTGATGCCCTCGAGTTAGGTAACCCATCGATCACGGAAAAGGACTA
TTGGGTGGTGTCTCTGCTTGCCATGTTGGAAAGCGTGGAAAGTGAGCACCACCAGCTTGTTTTTTCTGGTGGAACAGCTT
TGGCCAAGTCCAATATTAAGATTCTGCGAATGTCTGAAGACGTCGACATAAAATTGATTCCAACTCAGGAATTTCTCGAT
AAGGGAACTGGTGCGAAGAGAAAAGCTCGCAAAGCGTTAGTCGAGCACCTCATAACGAGGTTAGCGGACCACACTTATCT
GAATTATAGTGGTAAAACGGTACGTGATAGTTATCGCTATGTTGAAATCGAAATAGAGTACCCACAACAATACCATCAAG
CGCCGTGTCTAAGACCTTATATCAAACTGGAATTTATCGAGACAATCGAACTTCAGGGCGTTGAGCCTCGCTCTATTTCA
TCGCTGGTCGCGCAGAGCTACAATCAACCTGCCGAAGTAAGCACAATGTCGTGTATATCTATTGACTCGACGTTGGTTGA
AAAAGTGCTTTCCATGTTGCGTCGCACCATGTCAGTCAAGCGTGATCCACAGCGTAAGGATGACGAAACATTGGTTCGTC
ATATCTACGATGTTCACTGTATTAGCGCCGAGCATACGATTGATATGGGCGTATTAAAGCCGATGTTTGATACCGTTTTG
GAAGAAGACAGGGCGCGATATGGCAATCAACATCATGAGTTTGTCGATGATCCGCGCAATGAGTTAAAACTAGGATTAGA
AGAGCTAGAATCCAACGAGGAGTTTCGTAAACGTTTTGACGCGTTTGTTGCTCCAATGGTGTACAACACAGAGCCGCATG
ACTTTGATACCTGTTTTGCCTCATTCAAAGGTATTTCAGAGCAGCTTATTAGCTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15442.94 Da        Isoelectric Point: 10.7517

>AT58838 WP_064369853.1 NZ_CP013487:c43533-43129 [Vibrio alginolyticus]
MTATDLIYQKIKRSRRYVFERKDFDNYASYDQVGRVLKKLVDKGVLMKIGYGLYTKSTINSLTNKPMPTNPGGTDAIMRE
ILKMRGVDFELDAMSLKSINGQSTQIPASIRYKWDSKHFNRSLKVGNRVLSKRQ

Download         Length: 405 bp

>AT58838 NZ_CP013487:c43533-43129 [Vibrio alginolyticus]
ATGACAGCAACTGATCTTATTTATCAAAAGATAAAGCGCTCTCGACGCTATGTGTTCGAACGTAAAGACTTCGACAACTA
TGCTAGCTATGACCAGGTTGGTCGTGTATTGAAGAAACTTGTGGATAAAGGTGTGCTGATGAAAATCGGGTATGGTTTAT
ACACCAAGTCAACAATCAACAGCTTAACTAATAAACCGATGCCTACGAATCCCGGTGGTACTGACGCAATCATGCGTGAG
ATCCTAAAAATGCGCGGTGTAGACTTTGAGCTGGATGCTATGTCATTGAAGAGTATCAATGGACAGTCCACTCAAATACC
AGCGTCCATCAGGTACAAGTGGGACTCTAAGCATTTCAATCGCAGCCTTAAGGTTGGTAACAGAGTATTGAGCAAGCGAC
AATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References