Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 1723147..1724385 Replicon chromosome
Accession NZ_CP013480
Organism Pandoraea norimbergensis strain DSM 11628

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AT302_RS07750 Protein ID WP_058377934.1
Coordinates 1723147..1723710 (-) Length 188 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AT302_RS07755 Protein ID WP_058380177.1
Coordinates 1723843..1724385 (-) Length 181 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AT302_RS07720 1718874..1719086 + 213 WP_010806331.1 30S ribosomal protein S21 -
AT302_RS07725 1719262..1719735 + 474 WP_058377930.1 WbuC family cupin fold metalloprotein -
AT302_RS07730 1719823..1720926 - 1104 WP_157125718.1 hypothetical protein -
AT302_RS07735 1721199..1722074 - 876 WP_058377932.1 peptidoglycan-binding protein -
AT302_RS07740 1722589..1722963 + 375 WP_058377933.1 hypothetical protein -
AT302_RS07750 1723147..1723710 - 564 WP_058377934.1 HD domain-containing protein Toxin
AT302_RS07755 1723843..1724385 - 543 WP_058380177.1 helix-turn-helix domain-containing protein Antitoxin
AT302_RS07760 1724821..1725987 + 1167 WP_058377935.1 porin -
AT302_RS07765 1726176..1726973 + 798 WP_058377936.1 GntR family transcriptional regulator -
AT302_RS07770 1727032..1728243 + 1212 WP_058377937.1 ABC transporter substrate-binding protein -
AT302_RS07775 1728248..1729120 + 873 WP_058377938.1 branched-chain amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-167)

Antitoxin

Cro/C1-type helix-turn-helix domain

(8-58)


Sequences

Toxin        


Download         Length: 188 a.a.        Molecular weight: 20893.67 Da        Isoelectric Point: 4.5918

>T58805 WP_058377934.1 NZ_CP013480:c1723710-1723147 [Pandoraea norimbergensis]
MTQEQIEGRLNFLRTCERLKDVLRSGYTSSGRQESTAEHSWRLSLMAMLFMDQLGDVDSTKVLALCLVHDLGEALGGDVP
APAQLAGGSKDDVERRDLLTICEPLDAAMRAQIVGWWEEYVQATTPEARAVKALDKLETLLQHTQGLNPPDFDYAFNLAY
GRQYTDAIPLLRAVREQIDEATRARLA

Download         Length: 564 bp

>T58805 NZ_CP013480:c1723710-1723147 [Pandoraea norimbergensis]
ATGACGCAAGAACAGATCGAAGGCAGGCTGAATTTTCTGCGCACGTGTGAACGGCTGAAGGACGTGCTCAGAAGTGGCTA
CACGTCGTCCGGACGTCAGGAAAGCACCGCCGAGCACAGCTGGCGACTCAGTCTGATGGCGATGTTGTTCATGGATCAGT
TGGGCGACGTCGACAGTACGAAGGTGCTGGCGTTATGTCTTGTTCACGATCTGGGCGAAGCGTTGGGTGGCGACGTACCC
GCGCCGGCGCAGCTGGCGGGTGGCAGCAAGGACGACGTCGAGCGACGCGACCTGTTGACGATATGCGAACCGCTGGACGC
GGCGATGCGTGCGCAAATCGTCGGCTGGTGGGAGGAGTACGTGCAGGCAACGACGCCCGAAGCCCGCGCGGTCAAAGCGC
TCGACAAGCTCGAAACCCTGCTGCAACACACGCAGGGCCTTAATCCGCCGGACTTCGATTACGCGTTCAATCTGGCATAC
GGGCGGCAGTACACGGATGCGATACCACTGCTGCGTGCCGTGCGCGAACAGATCGACGAGGCGACAAGGGCGCGCCTCGC
CTAG

Antitoxin


Download         Length: 181 a.a.        Molecular weight: 19794.61 Da        Isoelectric Point: 8.7572

>AT58805 WP_058380177.1 NZ_CP013480:c1724385-1723843 [Pandoraea norimbergensis]
MPALAAPGATLRRWRVLRRIKQAHAAQWLGVSQSTVSRWEAGTLPITDDALARIEALFAARLDSAGDYALQRLVTYDARA
VHLVCDHTHRLLACSASRAAEFSQPLPILMGVSLWPFATEAIVAREASLRDAGWYEQRAPSIEFDTGSNASAEVPIRASR
CRWTRLTLSDGTVARLVETL

Download         Length: 543 bp

>AT58805 NZ_CP013480:c1724385-1723843 [Pandoraea norimbergensis]
ATGCCTGCGCTGGCGGCGCCCGGCGCGACGTTACGGCGGTGGCGCGTATTGCGACGTATCAAGCAGGCGCATGCGGCGCA
ATGGCTCGGCGTTTCGCAGTCGACAGTATCGCGCTGGGAAGCGGGTACGTTGCCGATCACGGACGATGCGCTCGCGCGTA
TCGAAGCGCTGTTCGCGGCGCGGCTGGACTCGGCGGGTGATTACGCGTTGCAACGGTTGGTGACGTACGACGCGCGCGCC
GTGCATCTCGTGTGCGATCACACGCATCGCTTGCTCGCGTGCTCCGCATCGCGTGCGGCGGAGTTTTCGCAGCCGTTGCC
GATATTGATGGGGGTGTCGTTGTGGCCCTTCGCGACCGAGGCGATCGTCGCGCGCGAAGCCTCACTGCGTGATGCGGGAT
GGTATGAACAGCGCGCGCCGTCGATCGAGTTCGATACCGGCAGCAATGCTTCGGCGGAGGTGCCGATTCGGGCCAGCCGC
TGCCGATGGACGCGCCTCACGCTCTCCGACGGCACCGTTGCGCGGCTGGTCGAGACGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References