58715

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 724796..725422 Replicon chromosome
Accession NZ_CP013464
Organism Burkholderia ubonensis strain MSMB1471WGS

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag WM29_RS19380 Protein ID WP_069237573.1
Coordinates 725099..725422 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag WM29_RS19375 Protein ID WP_060304541.1
Coordinates 724796..725095 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WM29_RS19345 720366..720842 + 477 WP_059618175.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
WM29_RS19350 720862..721188 + 327 WP_060304534.1 non-heme iron oxygenase ferredoxin subunit -
WM29_RS19355 721178..722398 + 1221 WP_069237572.1 FAD-dependent oxidoreductase -
WM29_RS19360 722489..723775 + 1287 WP_059592208.1 DUF445 family protein -
WM29_RS19365 723831..724133 - 303 WP_088505171.1 HigA family addiction module antidote protein -
WM29_RS19370 724146..724424 - 279 WP_042588736.1 type II toxin-antitoxin system RelE/ParE family toxin -
WM29_RS19375 724796..725095 - 300 WP_060304541.1 putative addiction module antidote protein Antitoxin
WM29_RS19380 725099..725422 - 324 WP_069237573.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
WM29_RS19385 725865..727505 + 1641 WP_069237574.1 acetolactate synthase large subunit -
WM29_RS19390 727535..728968 + 1434 WP_059967161.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-91)

Antitoxin

Uncharacterized protein HI1420

(3-95)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12164.90 Da        Isoelectric Point: 6.7166

>T58715 WP_069237573.1 NZ_CP013464:c725422-725099 [Burkholderia ubonensis]
MPYISPVFTIRTTEFFDAWFDALQDRIAKRRIQARIDRLAMGNPGDWKSVGAPVVEMRIDHGPGYRVYFVQRGSAWVVLL
CGGDKSTQQADIRAAHAMLEHLDLDTE

Download         Length: 324 bp

>T58715 NZ_CP013464:c725422-725099 [Burkholderia ubonensis]
ATGCCCTACATTTCTCCTGTATTCACCATCCGAACCACCGAGTTCTTCGACGCCTGGTTCGACGCGCTGCAGGATCGCAT
CGCGAAACGCCGTATCCAGGCACGCATCGACCGGCTGGCGATGGGCAATCCGGGCGACTGGAAGTCCGTCGGCGCGCCGG
TCGTCGAAATGCGCATCGACCACGGACCGGGGTATCGCGTCTACTTCGTGCAGCGGGGATCGGCTTGGGTGGTCCTGCTT
TGCGGCGGAGACAAGTCGACGCAACAGGCGGACATACGCGCCGCGCACGCGATGCTCGAGCATCTCGATCTCGATACGGA
GTAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10719.14 Da        Isoelectric Point: 6.3232

>AT58715 WP_060304541.1 NZ_CP013464:c725095-724796 [Burkholderia ubonensis]
MDTIKTRPWDSAEHLKTEDDMAEYFEACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGSKAHV

Download         Length: 300 bp

>AT58715 NZ_CP013464:c725095-724796 [Burkholderia ubonensis]
ATGGACACGATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTGAAGACCGAAGACGACATGGCCGAATACTTCGAAGC
CTGTCTGCAGGAGGCCGGCGACGATCCGGCCTTCATCGCGCACGCGCTCGGCGTGATCGCGCGTGCGCGCGGCATGTCAC
AGGTCGCGCGCGATGCGGGCCTGTCGCGCGAAGGTCTGTACAAGGCGCTGTCGCACGACGGCAACCCGAGCTTCGGCACG
ATCCTGAAGGTCATCAAGGCGCTCGGCCTGCAACTGCACGGCTCGAAAGCGCATGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References