Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 454684..455325 Replicon chromosome
Accession NZ_CP013455
Organism Burkholderia vietnamiensis strain MSMB608WGS

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag WL96_RS17675 Protein ID WP_011881500.1
Coordinates 454987..455325 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag WL96_RS17670 Protein ID WP_011881499.1
Coordinates 454684..454983 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WL96_RS17645 449791..451062 + 1272 WP_059462397.1 Rieske 2Fe-2S domain-containing protein -
WL96_RS17650 451080..451565 + 486 WP_034194948.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
WL96_RS17655 451592..451918 + 327 WP_011881496.1 non-heme iron oxygenase ferredoxin subunit -
WL96_RS17660 451908..453128 + 1221 WP_059462396.1 FAD-dependent oxidoreductase -
WL96_RS17665 453317..454603 + 1287 WP_014724584.1 DUF445 domain-containing protein -
WL96_RS17670 454684..454983 - 300 WP_011881499.1 putative addiction module antidote protein Antitoxin
WL96_RS17675 454987..455325 - 339 WP_011881500.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
WL96_RS17680 455682..457322 + 1641 WP_011881501.1 acetolactate synthase large subunit -
WL96_RS17685 457351..458784 + 1434 WP_045578203.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(16-106)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12642.42 Da        Isoelectric Point: 9.4958

>T58706 WP_011881500.1 NZ_CP013455:c455325-454987 [Burkholderia vietnamiensis]
MVDISSNVPYSAPTYSIRTTEVFDTWFAGLQDRVARRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYYVRRA
TIWVILLCGGDKSTQQADIRAAHAMLGRLDLE

Download         Length: 339 bp

>T58706 NZ_CP013455:c455325-454987 [Burkholderia vietnamiensis]
ATGGTTGACATATCGAGTAACGTGCCTTACAGTGCTCCGACGTACAGCATCAGAACGACCGAAGTCTTCGACACATGGTT
CGCCGGTCTGCAGGATCGCGTCGCACGGCGGCGTATCCAGGCCCGCATCGACCGCCTGTCGATGGGCAATCCGGGCGACT
GGAAGTCGGCCGGCTCCCCGGTCGTCGAGATGCGTATCGACCACGGCCCCGGCTATCGCGTCTACTACGTCAGGCGCGCG
ACGATCTGGGTGATCCTGCTCTGCGGCGGCGACAAGTCGACGCAACAGGCAGACATTCGCGCCGCGCACGCAATGCTCGG
GCGGCTCGACCTGGAGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10548.87 Da        Isoelectric Point: 6.0633

>AT58706 WP_011881499.1 NZ_CP013455:c454983-454684 [Burkholderia vietnamiensis]
MDKISTRPWDSAAHLETDDDIADYFDACLQEGGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKARA

Download         Length: 300 bp

>AT58706 NZ_CP013455:c454983-454684 [Burkholderia vietnamiensis]
ATGGACAAGATCAGCACCCGGCCGTGGGATTCGGCCGCCCACCTCGAAACCGACGACGACATCGCCGACTATTTCGACGC
GTGCCTGCAGGAAGGCGGCGACGACCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCGCGCGCGCGCGGCATGTCGC
AGGTCGCCCGCGACGCCGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTCAAAGTGATCAAGGCGCTCGGCCTGCAACTGCACGGCGCGAAAGCGCGCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References