Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 775369..775995 Replicon chromosome
Accession NZ_CP013447
Organism Burkholderia ubonensis strain MSMB1189WGS isolate MSMB1189WGS

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag WK67_RS23725 Protein ID WP_069271003.1
Coordinates 775672..775995 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag WK67_RS23720 Protein ID WP_010089041.1
Coordinates 775369..775668 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WK67_RS23695 770625..771896 + 1272 WP_045564529.1 Rieske 2Fe-2S domain-containing protein -
WK67_RS23700 771911..772387 + 477 WP_010089037.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
WK67_RS23705 772407..772733 + 327 WP_045564530.1 non-heme iron oxygenase ferredoxin subunit -
WK67_RS23710 772723..773943 + 1221 WP_069271001.1 FAD-dependent oxidoreductase -
WK67_RS23715 774034..775320 + 1287 WP_069271002.1 DUF445 family protein -
WK67_RS23720 775369..775668 - 300 WP_010089041.1 putative addiction module antidote protein Antitoxin
WK67_RS23725 775672..775995 - 324 WP_069271003.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
WK67_RS23730 776409..778049 + 1641 WP_059715141.1 acetolactate synthase large subunit -
WK67_RS23735 778079..779512 + 1434 WP_059481051.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(9-101)

Antitoxin

Uncharacterized protein HI1420

(4-95)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12110.70 Da        Isoelectric Point: 6.7164

>T58691 WP_069271003.1 NZ_CP013447:c775995-775672 [Burkholderia ubonensis]
MPYSPPVFTIRTTEFFDAWFDALQDRIAKRRIQARIDRLATGNPGDWKSVGASVVEMRIDHGPGYRVYYAQRGSAWVILL
CGGDKSTQQADIRAAHAMLEHLDLDTE

Download         Length: 324 bp

>T58691 NZ_CP013447:c775995-775672 [Burkholderia ubonensis]
ATGCCCTACAGTCCTCCTGTATTCACCATCCGAACCACCGAGTTCTTCGACGCCTGGTTCGACGCGCTGCAGGATCGCAT
CGCGAAACGCCGTATCCAGGCGCGCATCGACCGCCTGGCGACGGGCAATCCGGGCGACTGGAAATCCGTCGGCGCGTCGG
TCGTCGAAATGCGCATCGACCACGGCCCGGGGTATCGCGTCTACTACGCGCAGCGGGGATCGGCTTGGGTGATCCTGCTT
TGCGGCGGAGACAAGTCGACGCAACAGGCGGACATACGCGCCGCGCACGCGATGCTCGAGCATCTCGATCTCGATACGGA
GTAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10718.16 Da        Isoelectric Point: 6.6390

>AT58691 WP_010089041.1 NZ_CP013447:c775668-775369 [Burkholderia ubonensis]
MDKIKTRPWDSAEHLKTEDDMAEYFEACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGSKAHA

Download         Length: 300 bp

>AT58691 NZ_CP013447:c775668-775369 [Burkholderia ubonensis]
ATGGACAAGATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTGAAGACCGAAGACGACATGGCCGAATACTTCGAAGC
CTGTCTGCAGGAGGCCGGCGACGATCCGGCCTTCATCGCGCACGCGCTCGGCGTGATCGCGCGCGCGCGCGGCATGTCAC
AGGTCGCGCGCGATGCGGGCCTGTCGCGCGAAGGTCTGTACAAGGCGCTGTCGCACGACGGCAACCCGAGCTTCGGCACG
ATCCTGAAGGTCATCAAGGCGCTCGGCCTGCAACTGCACGGCTCGAAAGCGCACGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References