Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1224087..1224728 Replicon chromosome
Accession NZ_CP013433
Organism Burkholderia vietnamiensis strain AU1233

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag WK23_RS05400 Protein ID WP_011881500.1
Coordinates 1224390..1224728 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag WK23_RS05395 Protein ID WP_011881499.1
Coordinates 1224087..1224386 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WK23_RS05370 1219183..1220454 + 1272 WP_014724582.1 Rieske 2Fe-2S domain-containing protein -
WK23_RS05375 1220472..1220957 + 486 WP_034194948.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
WK23_RS05380 1220984..1221310 + 327 WP_045578207.1 non-heme iron oxygenase ferredoxin subunit -
WK23_RS05385 1221300..1222520 + 1221 WP_059895580.1 FAD-dependent oxidoreductase -
WK23_RS05390 1222709..1223995 + 1287 WP_069263474.1 DUF445 domain-containing protein -
WK23_RS05395 1224087..1224386 - 300 WP_011881499.1 putative addiction module antidote protein Antitoxin
WK23_RS05400 1224390..1224728 - 339 WP_011881500.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
WK23_RS05405 1225083..1226723 + 1641 WP_069263476.1 acetolactate synthase large subunit -
WK23_RS05410 1226752..1228185 + 1434 WP_011881502.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(16-106)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12642.42 Da        Isoelectric Point: 9.4958

>T58659 WP_011881500.1 NZ_CP013433:c1224728-1224390 [Burkholderia vietnamiensis]
MVDISSNVPYSAPTYSIRTTEVFDTWFAGLQDRVARRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYYVRRA
TIWVILLCGGDKSTQQADIRAAHAMLGRLDLE

Download         Length: 339 bp

>T58659 NZ_CP013433:c1224728-1224390 [Burkholderia vietnamiensis]
ATGGTTGACATATCGAGTAACGTGCCTTACAGTGCTCCGACGTACAGCATCAGAACGACCGAAGTCTTCGACACATGGTT
CGCCGGTCTGCAGGATCGCGTCGCACGGCGGCGCATCCAGGCCCGCATCGACCGCCTGTCGATGGGCAATCCGGGCGACT
GGAAGTCGGCCGGCTCCCCGGTCGTCGAGATGCGTATCGACCACGGCCCCGGCTATCGCGTCTACTACGTCAGGCGCGCG
ACGATCTGGGTGATCCTGCTCTGCGGCGGCGACAAGTCGACGCAACAGGCAGACATTCGCGCCGCGCACGCAATGCTCGG
GCGGCTCGACCTGGAGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10548.87 Da        Isoelectric Point: 6.0633

>AT58659 WP_011881499.1 NZ_CP013433:c1224386-1224087 [Burkholderia vietnamiensis]
MDKISTRPWDSAAHLETDDDIADYFDACLQEGGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKARA

Download         Length: 300 bp

>AT58659 NZ_CP013433:c1224386-1224087 [Burkholderia vietnamiensis]
ATGGACAAGATCAGCACCCGGCCGTGGGATTCGGCCGCCCACCTCGAAACCGACGACGACATCGCCGACTATTTCGACGC
GTGCCTGCAGGAAGGCGGCGACGACCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCGCGCGCGCGCGGCATGTCGC
AGGTCGCACGCGACGCCGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACC
ATCCTCAAAGTGATCAAGGCGCTCGGCCTGCAACTGCACGGCGCGAAAGCGCGCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References