Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1962708..1964458 Replicon chromosome
Accession NZ_CP013400
Organism Burkholderia seminalis strain FL-5-4-10-S1-D7

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag WJ12_RS29390 Protein ID WP_059557590.1
Coordinates 1963562..1964458 (-) Length 299 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag WJ12_RS29385 Protein ID WP_034189895.1
Coordinates 1962708..1963565 (-) Length 286 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WJ12_RS29365 1957883..1959373 - 1491 WP_034189891.1 aldehyde dehydrogenase -
WJ12_RS29370 1959446..1960261 - 816 WP_069245957.1 aspartate dehydrogenase -
WJ12_RS29375 1960254..1961921 - 1668 WP_069245958.1 thiamine pyrophosphate-binding protein -
WJ12_RS29380 1961914..1962711 - 798 WP_049030514.1 SDR family oxidoreductase -
WJ12_RS29385 1962708..1963565 - 858 WP_034189895.1 IclR family transcriptional regulator Antitoxin
WJ12_RS29390 1963562..1964458 - 897 WP_059557590.1 alpha/beta fold hydrolase Toxin
WJ12_RS29395 1964477..1965004 - 528 WP_034189947.1 cupin domain-containing protein -
WJ12_RS29400 1965034..1965804 - 771 WP_069245959.1 SDR family oxidoreductase -
WJ12_RS29405 1965797..1966867 - 1071 WP_034189898.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
WJ12_RS29410 1966922..1967233 - 312 WP_034189899.1 hypothetical protein -
WJ12_RS29415 1967235..1967552 - 318 WP_006489883.1 non-heme iron oxygenase ferredoxin subunit -
WJ12_RS29420 1967999..1969078 + 1080 WP_069245960.1 porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(51-279)

Antitoxin

Transcription regulator IclR, N-terminal

(24-72)


Sequences

Toxin        


Download         Length: 299 a.a.        Molecular weight: 30536.78 Da        Isoelectric Point: 8.0700

>T58590 WP_059557590.1 NZ_CP013400:c1964458-1963562 [Burkholderia seminalis]
MSVIDKRERDRTAAFAALLGQFPEQRCAAGAAGTIGYREAGAQHAGRALPVVLLHGIGSGAASWVRQLDTLGASRRVLAW
DAPGYGVSTPVHGASPDAADYAASLNAWLEALGIERCVLVGHSLGAIVAGGLARAMPARIAGLLLVSPAGGYGSAPADTR
DARRDARLAMLAALGPAGLAEQRSGNMLSGFANEEAKAWVRWNMARIVPAGYAQATHLLANADLATDLAGFRGRTAVAVG
AHDAITPPAACERIAAAAHVALQVIPQAGHAGYVEAPAVYSALIDGFCRQCDPQRGLA

Download         Length: 897 bp

>T58590 NZ_CP013400:c1964458-1963562 [Burkholderia seminalis]
ATGAGTGTCATCGACAAACGTGAACGCGACCGCACCGCGGCGTTCGCCGCGCTGCTCGGGCAGTTTCCCGAGCAGCGTTG
CGCGGCCGGCGCGGCGGGCACGATCGGTTACCGCGAGGCCGGCGCGCAGCATGCGGGCCGCGCGCTGCCCGTCGTGCTGC
TGCACGGGATCGGCTCGGGCGCCGCATCGTGGGTTCGCCAGCTCGACACGCTCGGCGCGTCGCGGCGCGTGCTCGCATGG
GATGCGCCCGGTTACGGCGTGTCGACGCCCGTGCACGGCGCGTCGCCGGATGCCGCCGATTACGCGGCATCGCTGAACGC
GTGGCTCGAGGCACTCGGCATCGAACGCTGCGTGCTGGTCGGTCATTCGCTCGGCGCGATCGTCGCGGGCGGTCTCGCCC
GCGCGATGCCTGCGCGGATCGCCGGCCTGCTGCTGGTATCGCCCGCGGGCGGTTACGGCAGCGCGCCGGCCGATACGCGC
GACGCGCGCCGCGACGCGCGGCTCGCGATGCTCGCGGCGCTCGGCCCGGCCGGGCTCGCCGAGCAGCGCAGCGGCAACAT
GCTGTCCGGTTTCGCGAACGAGGAAGCGAAGGCGTGGGTGCGCTGGAACATGGCGCGCATCGTGCCGGCCGGCTACGCGC
AGGCCACGCATCTGCTCGCGAATGCCGATCTCGCGACCGATCTCGCCGGCTTTCGCGGCCGCACGGCCGTGGCCGTCGGC
GCGCACGACGCGATCACGCCGCCCGCCGCGTGCGAGCGGATCGCCGCGGCCGCGCACGTCGCGCTACAGGTGATTCCGCA
AGCAGGCCACGCCGGCTACGTGGAAGCGCCGGCCGTTTATTCCGCCTTGATCGACGGTTTCTGCCGTCAATGCGACCCAC
AGCGGGGGCTGGCATGA

Antitoxin


Download         Length: 286 a.a.        Molecular weight: 31305.85 Da        Isoelectric Point: 7.1325

>AT58590 WP_034189895.1 NZ_CP013400:c1963565-1962708 [Burkholderia seminalis]
MSEPLQRPASEHAKADANYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNYK
LGIAVLRLGFEYLSSLELTDLGLPVIESLRDATGFTTHIVIRDGRDVVFVAKAQSQSPVFSSIRVNVGTRLPAHATTHGH
VLMGDLSLKELHALYPEGALTRMTSATPETVDALYDVIREDALRGYGVSNSSFERGISVVTAPVRNETQKIVACITVTVP
RPEIDAALIADGLIDKVQRAAAELSRRLNYRSDDEHTFLKALGLR

Download         Length: 858 bp

>AT58590 NZ_CP013400:c1963565-1962708 [Burkholderia seminalis]
ATGAGCGAACCGCTGCAACGACCGGCATCCGAACACGCGAAGGCCGACGCGAACTATGTGGTGCCGGGCCTCGAACGCGG
GCTGCGGATTCTGGCCGAATTCTCGCCGCGCGAGCCGGTGCTCGGCGCGCCCGAACTGTCGAAGCGGCTCGGCATTCCGC
GCACGACGGTGTTCCGTCTGCTGCAGACGCTCGAATCGCTCGGCTTTCTCGAGCGTGCGGACAAGGATCGCAACTACAAG
CTCGGCATCGCCGTGTTGCGGCTCGGCTTCGAATACCTGAGCTCGCTGGAGCTGACCGATCTCGGCCTGCCGGTGATCGA
AAGCCTGCGCGATGCGACCGGCTTCACGACGCACATCGTGATCCGCGACGGCCGCGACGTGGTGTTCGTCGCAAAGGCGC
AGAGCCAGTCGCCGGTGTTCAGCTCGATCCGCGTGAACGTCGGCACGCGCCTGCCCGCGCATGCGACGACCCACGGCCAC
GTGCTGATGGGCGACCTGTCGCTGAAGGAACTGCATGCGCTGTATCCGGAAGGCGCGCTGACCCGGATGACGAGCGCGAC
GCCGGAAACGGTCGACGCGCTGTACGACGTGATCCGCGAGGATGCGCTGCGCGGCTACGGCGTCAGCAATTCGTCGTTCG
AGCGCGGCATCTCGGTGGTCACGGCGCCGGTGCGCAACGAGACGCAGAAGATCGTCGCGTGCATCACGGTGACGGTGCCG
CGTCCGGAGATCGACGCGGCGCTGATCGCGGACGGGCTGATCGACAAGGTGCAGCGCGCGGCGGCGGAATTGTCGCGGCG
GCTCAATTACCGCTCGGATGACGAGCACACGTTTCTGAAGGCTTTAGGACTCCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References