Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 735596..736237 Replicon chromosome
Accession NZ_CP013400
Organism Burkholderia seminalis strain FL-5-4-10-S1-D7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag WJ12_RS24090 Protein ID WP_069245878.1
Coordinates 735899..736237 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag WJ12_RS24085 Protein ID WP_069245877.1
Coordinates 735596..735895 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WJ12_RS24060 730800..732071 + 1272 WP_049029683.1 Rieske 2Fe-2S domain-containing protein -
WJ12_RS24065 732086..732562 + 477 WP_006490977.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
WJ12_RS24070 732580..732906 + 327 WP_006479527.1 non-heme iron oxygenase ferredoxin subunit -
WJ12_RS24075 732896..734116 + 1221 WP_069245876.1 FAD-dependent oxidoreductase -
WJ12_RS24080 734226..735512 + 1287 WP_034185659.1 DUF445 domain-containing protein -
WJ12_RS24085 735596..735895 - 300 WP_069245877.1 putative addiction module antidote protein Antitoxin
WJ12_RS24090 735899..736237 - 339 WP_069245878.1 addiction module protein Toxin
WJ12_RS24095 736575..738215 + 1641 WP_034185662.1 acetolactate synthase large subunit -
WJ12_RS24100 738245..739678 + 1434 WP_034185663.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(18-109)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12604.44 Da        Isoelectric Point: 11.2163

>T58589 WP_069245878.1 NZ_CP013400:c736237-735899 [Burkholderia seminalis]
MVYILPSAPYRAPTFSARTSDVFDTWFAGRQDRVAKRRIQARIDRLSMGNPGDRKSAGSPVVEMRIDHGPGYRIYSVRRG
PIRVILRCGGDQSTQQADIRAAHAMLARLDME

Download         Length: 339 bp

>T58589 NZ_CP013400:c736237-735899 [Burkholderia seminalis]
ATGGTTTACATACTGCCATCGGCGCCCTACCGTGCACCTACGTTCAGTGCCCGAACCAGCGACGTCTTCGACACCTGGTT
TGCCGGCCGGCAGGATCGCGTCGCGAAGCGCCGCATCCAGGCTCGCATCGACCGCCTGTCGATGGGCAACCCCGGCGACC
GGAAGTCCGCCGGCTCGCCGGTCGTCGAAATGCGGATCGATCATGGCCCCGGCTATCGCATCTACTCCGTCCGGCGCGGA
CCGATCCGGGTCATCCTGCGCTGCGGCGGCGATCAATCGACGCAACAGGCCGACATACGCGCCGCGCACGCGATGCTCGC
GCGCCTCGACATGGAATGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10733.17 Da        Isoelectric Point: 6.4777

>AT58589 WP_069245877.1 NZ_CP013400:c735895-735596 [Burkholderia seminalis]
MDKIRTRPWNSAEPLKTEDDMADYFEACLQEAGDDPAFIAHALGVIARARDMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKAHA

Download         Length: 300 bp

>AT58589 NZ_CP013400:c735895-735596 [Burkholderia seminalis]
ATGGACAAGATCCGCACCCGACCGTGGAATTCGGCCGAACCCCTGAAAACCGAAGACGACATGGCCGACTACTTCGAGGC
CTGCCTGCAGGAGGCCGGCGACGATCCGGCCTTCATCGCGCACGCGCTCGGCGTGATCGCACGCGCACGCGACATGTCGC
AGGTCGCGCGCGATGCGGGCCTGTCGCGCGAAGGGTTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAAGTCATCAAGGCGCTCGGCCTGCAGCTGCACGGCGCGAAAGCGCACGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References