Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 496285..496926 Replicon chromosome
Accession NZ_CP013394
Organism Burkholderia vietnamiensis strain FL-2-3-30-S1-D0

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag WJ02_RS16725 Protein ID WP_011881500.1
Coordinates 496588..496926 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag WJ02_RS16720 Protein ID WP_059494486.1
Coordinates 496285..496584 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WJ02_RS16695 491392..492663 + 1272 WP_069222858.1 Rieske 2Fe-2S domain-containing protein -
WJ02_RS16700 492681..493166 + 486 WP_034194948.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
WJ02_RS16705 493193..493519 + 327 WP_069222859.1 non-heme iron oxygenase ferredoxin subunit -
WJ02_RS16710 493509..494729 + 1221 WP_059702812.1 FAD-dependent oxidoreductase -
WJ02_RS16715 494918..496204 + 1287 WP_014724584.1 DUF445 domain-containing protein -
WJ02_RS16720 496285..496584 - 300 WP_059494486.1 putative addiction module antidote protein Antitoxin
WJ02_RS16725 496588..496926 - 339 WP_011881500.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
WJ02_RS16730 497283..498923 + 1641 WP_059463465.1 acetolactate synthase large subunit -
WJ02_RS16735 498952..500385 + 1434 WP_059453473.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(16-106)

Antitoxin

Uncharacterized protein HI1420

(5-96)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12642.42 Da        Isoelectric Point: 9.4958

>T58585 WP_011881500.1 NZ_CP013394:c496926-496588 [Burkholderia vietnamiensis]
MVDISSNVPYSAPTYSIRTTEVFDTWFAGLQDRVARRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYYVRRA
TIWVILLCGGDKSTQQADIRAAHAMLGRLDLE

Download         Length: 339 bp

>T58585 NZ_CP013394:c496926-496588 [Burkholderia vietnamiensis]
ATGGTTGACATATCGAGTAACGTGCCTTACAGTGCTCCGACGTACAGCATCAGAACGACCGAAGTCTTCGACACATGGTT
CGCCGGTTTGCAGGATCGCGTCGCACGGCGGCGCATCCAGGCCCGCATCGACCGCCTGTCGATGGGCAATCCGGGCGACT
GGAAGTCGGCCGGCTCCCCGGTCGTCGAGATGCGTATCGACCACGGCCCCGGCTATCGCGTCTACTACGTCAGGCGCGCG
ACGATCTGGGTGATCCTGCTCTGCGGCGGCGACAAGTCGACGCAACAGGCAGACATTCGCGCCGCGCACGCAATGCTCGG
GCGGCTCGACCTGGAGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10490.84 Da        Isoelectric Point: 6.4756

>AT58585 WP_059494486.1 NZ_CP013394:c496584-496285 [Burkholderia vietnamiensis]
MDKISTRPWDSAAHLETDDDIAGYFDACLQEGGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKARA

Download         Length: 300 bp

>AT58585 NZ_CP013394:c496584-496285 [Burkholderia vietnamiensis]
ATGGACAAGATCAGCACCCGGCCGTGGGATTCGGCCGCCCACCTCGAAACCGACGACGACATCGCCGGCTATTTCGACGC
ATGCCTGCAGGAAGGCGGCGACGACCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCGCGCGCGCGCGGCATGTCGC
AGGTCGCACGCGACGCCGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACC
ATCCTCAAAGTGATCAAGGCGCTCGGCCTGCAACTGCACGGCGCGAAAGCGCGCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References