Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1398604..1399243 Replicon chromosome
Accession NZ_CP013377
Organism Burkholderia pseudomultivorans strain SUB-INT23-BP2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag WS57_RS05935 Protein ID WP_059517234.1
Coordinates 1398827..1399243 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag WS57_RS05930 Protein ID WP_059517236.1
Coordinates 1398604..1398840 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WS57_RS05905 1393712..1394455 + 744 WP_009695636.1 GntR family transcriptional regulator -
WS57_RS05910 1394469..1395320 + 852 WP_009695637.1 sulfite exporter TauE/SafE family protein -
WS57_RS05915 1395317..1395640 + 324 WP_059517240.1 DUF1634 domain-containing protein -
WS57_RS05920 1396440..1397132 + 693 WP_081337611.1 TonB-dependent receptor -
WS57_RS35470 1397290..1398276 - 987 WP_059517238.1 hypothetical protein -
WS57_RS05930 1398604..1398840 + 237 WP_059517236.1 hypothetical protein Antitoxin
WS57_RS05935 1398827..1399243 + 417 WP_059517234.1 type II toxin-antitoxin system VapC family toxin Toxin
WS57_RS05940 1399454..1400350 + 897 WP_040131700.1 VOC family protein -
WS57_RS05945 1400360..1401253 + 894 WP_059480270.1 CoA transferase subunit A -
WS57_RS05950 1401264..1402061 + 798 WP_069243872.1 ketoacid CoA transferase -
WS57_RS05955 1402070..1403008 + 939 WP_060296220.1 enoyl-CoA hydratase -
WS57_RS05960 1403005..1404093 + 1089 WP_009695646.1 nitronate monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15443.68 Da        Isoelectric Point: 9.7278

>T58548 WP_059517234.1 NZ_CP013377:1398827-1399243 [Burkholderia pseudomultivorans]
MYLVDTNVISETRKKTRANAGVLSFFRQARDNNDPLYLSIVTISELQRGVDLVRFRGDAKQAARLDAWLATIVQDHARHV
LTVDAEIAQLWGRLRVPQPDHALDKLIAATALIHDLTVVTRNAGDFARTGVKLLNPFD

Download         Length: 417 bp

>T58548 NZ_CP013377:1398827-1399243 [Burkholderia pseudomultivorans]
ATGTATTTGGTTGACACGAACGTCATCAGCGAAACACGCAAGAAAACGCGCGCCAATGCCGGCGTGCTCTCGTTCTTCCG
ACAGGCGCGCGACAACAACGACCCGCTGTACCTGTCGATCGTGACGATTTCCGAGCTGCAGCGCGGCGTCGATCTCGTGC
GCTTTCGCGGCGACGCGAAACAGGCGGCCCGGCTCGATGCATGGCTCGCGACGATCGTGCAGGACCATGCGCGCCATGTA
CTGACCGTCGACGCCGAAATCGCGCAGCTCTGGGGCCGCCTGCGCGTGCCGCAGCCCGACCACGCACTCGACAAGCTGAT
CGCCGCCACCGCGCTGATCCACGACCTGACGGTCGTCACCCGCAACGCCGGCGATTTCGCGCGAACCGGCGTGAAACTCC
TGAACCCGTTCGACTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8544.51 Da        Isoelectric Point: 6.0723

>AT58548 WP_059517236.1 NZ_CP013377:1398604-1398840 [Burkholderia pseudomultivorans]
MPDLLVRNVDKAVIQSLREQAAAHGRSAEAEHRAILADALHRPKRRSLAEVLASMPNVGEDADFERRDDSGEGSHVFG

Download         Length: 237 bp

>AT58548 NZ_CP013377:1398604-1398840 [Burkholderia pseudomultivorans]
ATGCCTGATCTTCTGGTGCGAAATGTAGACAAGGCCGTCATCCAGAGTCTGCGCGAGCAGGCCGCGGCGCATGGCCGCAG
CGCCGAAGCGGAGCATCGGGCCATTCTGGCCGACGCGCTGCACCGCCCGAAACGCCGAAGCCTGGCCGAGGTGCTGGCAA
GCATGCCGAACGTGGGCGAAGACGCCGATTTCGAGCGCCGGGACGATTCCGGCGAGGGGTCTCATGTATTTGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References