Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 2918319..2918838 Replicon chromosome
Accession NZ_CP013371
Organism Burkholderia ubonensis strain RF23-BP41

Toxin (Protein)


Gene name stbE Uniprot ID A0A102LUV3
Locus tag WI31_RS34165 Protein ID WP_059610553.1
Coordinates 2918319..2918600 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A102WW84
Locus tag WI31_RS34170 Protein ID WP_059610554.1
Coordinates 2918590..2918838 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WI31_RS34150 2914820..2915929 + 1110 WP_059610551.1 AGE family epimerase/isomerase -
WI31_RS34155 2915902..2917518 - 1617 WP_059634855.1 Tar ligand binding domain-containing protein -
WI31_RS34160 2917766..2918209 + 444 WP_010090127.1 PaaI family thioesterase -
WI31_RS34165 2918319..2918600 - 282 WP_059610553.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
WI31_RS34170 2918590..2918838 - 249 WP_059610554.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
WI31_RS34175 2918982..2920043 - 1062 WP_059653599.1 CoA transferase -
WI31_RS34180 2920168..2921358 - 1191 WP_059653455.1 2-methylaconitate cis-trans isomerase PrpF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-78)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10967.84 Da        Isoelectric Point: 10.7091

>T58521 WP_059610553.1 NZ_CP013371:c2918600-2918319 [Burkholderia ubonensis]
MTFELAFLEPALREWKKLDRTVRDQFKSKLAERLENPRVPSAKLHGHPDRYKIKLRSAGYRLVYEVRDTEVIVLVVAVGR
RERDAVYLAAMKR

Download         Length: 282 bp

>T58521 NZ_CP013371:c2918600-2918319 [Burkholderia ubonensis]
ATGACCTTTGAACTCGCATTTCTCGAACCTGCATTGAGAGAGTGGAAGAAGCTTGATCGCACAGTTCGCGACCAGTTCAA
ATCCAAACTCGCCGAGCGGCTTGAAAATCCTCGCGTCCCCTCGGCAAAGCTGCACGGCCACCCGGATCGCTACAAGATCA
AGCTACGCAGCGCCGGCTACCGACTCGTTTACGAAGTGCGCGACACGGAGGTCATCGTGCTGGTTGTCGCAGTCGGTCGG
CGCGAGCGCGATGCAGTCTATCTTGCCGCAATGAAACGTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8975.37 Da        Isoelectric Point: 5.0636

>AT58521 WP_059610554.1 NZ_CP013371:c2918838-2918590 [Burkholderia ubonensis]
MPHTILASVTASVSELKRNPMGTVAAGEGFPVAILNHNEPAFYCIPAKTWEAMLERLEDIEDNALADARIKEKAVKVKLN
DL

Download         Length: 249 bp

>AT58521 NZ_CP013371:c2918838-2918590 [Burkholderia ubonensis]
ATGCCTCACACCATCCTGGCAAGCGTTACGGCGAGCGTCTCCGAGCTGAAGCGGAACCCGATGGGAACCGTCGCGGCGGG
AGAGGGTTTCCCGGTGGCGATCCTGAACCACAACGAACCGGCGTTCTATTGCATCCCGGCGAAGACTTGGGAGGCGATGC
TCGAACGTCTGGAGGATATCGAGGACAACGCGCTGGCTGATGCGCGTATCAAGGAGAAGGCCGTCAAGGTCAAGCTGAAT
GACCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A102LUV3

Antitoxin

Source ID Structure
AlphaFold DB A0A102WW84

References