58518

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1962330..1964095 Replicon chromosome
Accession NZ_CP013371
Organism Burkholderia ubonensis strain RF23-BP41

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag WI31_RS29945 Protein ID WP_059650882.1
Coordinates 1963178..1964095 (-) Length 306 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag WI31_RS29940 Protein ID WP_059650885.1
Coordinates 1962330..1963181 (-) Length 284 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WI31_RS29920 1957534..1959024 - 1491 WP_059612492.1 aldehyde dehydrogenase -
WI31_RS29925 1959047..1959880 - 834 WP_059612494.1 aspartate dehydrogenase -
WI31_RS29930 1959873..1961540 - 1668 WP_059615836.1 thiamine pyrophosphate-binding protein -
WI31_RS29935 1961533..1962330 - 798 WP_059615835.1 SDR family oxidoreductase -
WI31_RS29940 1962330..1963181 - 852 WP_059650885.1 IclR family transcriptional regulator Antitoxin
WI31_RS29945 1963178..1964095 - 918 WP_059650882.1 alpha/beta fold hydrolase Toxin
WI31_RS29950 1964114..1964641 - 528 WP_059612750.1 cupin domain-containing protein -
WI31_RS29955 1964671..1965441 - 771 WP_059650881.1 SDR family oxidoreductase -
WI31_RS29960 1965434..1966504 - 1071 WP_059650879.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
WI31_RS29965 1966551..1966862 - 312 WP_059650877.1 hypothetical protein -
WI31_RS29970 1966866..1967183 - 318 WP_017329029.1 non-heme iron oxygenase ferredoxin subunit -
WI31_RS29975 1967621..1968700 + 1080 WP_042588195.1 porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(58-286)

Antitoxin

Transcription regulator IclR, C-terminal

(142-265)


Sequences

Toxin        


Download         Length: 306 a.a.        Molecular weight: 31362.73 Da        Isoelectric Point: 8.8229

>T58518 WP_059650882.1 NZ_CP013371:c1964095-1963178 [Burkholderia ubonensis]
MSVIDKRERDRERIASFATLLERFPEQRSPAGAAGTIGYRAAGVQHAGRALAGRTLPVVLLHGIGSGAASWVRQLDALGA
SRRVLAWDAPGYGASTPVHGASPAAADYAAALAAWLDALGIDRCVLVGHSLGAIVAGGFARVMPERVAGLLLISPAGGYG
SAPAETRASRRDARLAMLDELGPAGLAAQRSGNMLSGNASEDARAWVRWNMARIVPAGYAQATHLLANADLASDLAAFRG
RAAVAVGANDAITPPAACERIAAALHVGLQVIPQAGHAGYVEAPAVYSALIDAFCRQCDLQRGPA

Download         Length: 918 bp

>T58518 NZ_CP013371:c1964095-1963178 [Burkholderia ubonensis]
ATGAGTGTCATCGACAAACGTGAACGCGACCGCGAGCGCATCGCGAGCTTCGCGACGCTGCTCGAGCGGTTTCCCGAGCA
GCGCTCGCCGGCCGGCGCGGCGGGCACGATCGGCTACCGCGCGGCCGGCGTGCAGCATGCGGGCCGCGCCTTGGCCGGTC
GCACGCTCCCCGTCGTGCTGCTGCACGGGATCGGCTCGGGCGCCGCTTCGTGGGTGCGCCAGCTCGATGCGCTCGGCGCT
TCGCGGCGCGTGCTCGCATGGGACGCGCCCGGCTACGGTGCGTCGACGCCGGTGCACGGCGCGTCGCCGGCCGCCGCCGA
TTACGCGGCGGCGCTCGCCGCATGGCTCGATGCGCTCGGCATCGACCGCTGCGTGCTGGTCGGCCACTCGCTCGGCGCGA
TCGTCGCGGGCGGCTTCGCCCGCGTGATGCCGGAGCGCGTTGCCGGGCTGCTGCTGATCTCGCCCGCGGGCGGCTACGGC
AGCGCGCCGGCCGAGACGCGCGCATCGCGCCGCGACGCGCGGCTCGCGATGCTCGACGAACTCGGCCCGGCCGGGCTCGC
GGCGCAGCGCAGCGGCAACATGCTGTCCGGTAACGCGAGCGAGGACGCACGCGCATGGGTGCGCTGGAACATGGCGCGCA
TCGTGCCGGCCGGCTACGCACAGGCGACGCACTTGCTCGCGAACGCCGATCTCGCGTCGGACCTTGCGGCCTTTCGCGGC
CGCGCGGCGGTGGCCGTCGGCGCGAACGACGCGATCACGCCGCCCGCCGCGTGCGAGCGGATCGCCGCGGCTTTGCACGT
CGGGCTGCAGGTGATTCCGCAGGCCGGACATGCGGGCTACGTGGAAGCGCCGGCCGTCTATTCCGCACTGATCGACGCGT
TCTGCCGTCAGTGCGACCTGCAGCGGGGGCCGGCATGA

Antitoxin


Download         Length: 284 a.a.        Molecular weight: 30944.37 Da        Isoelectric Point: 6.3566

>AT58518 WP_059650885.1 NZ_CP013371:c1963181-1962330 [Burkholderia ubonensis]
MSEPLLNENDGAKGDANYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNYKL
GIAVLRLGFEYLSSLELTDLGLPVIESLRDATGFTTHIVIRDGRDVVFVAKAQSQAPVFSSIRVNVGTRLPAHATTHGHV
LMGDLSLGELRALYPEGALNRMTNATPDTVDALYDVIREDALRGYGVSNSSFERGISVVTAPVRNDTQKIVACITVTVPR
PEIDAALIADGLIDKVRRAAAELSRRLNYRSDDEHTFLKALGL

Download         Length: 852 bp

>AT58518 NZ_CP013371:c1963181-1962330 [Burkholderia ubonensis]
ATGAGCGAACCGCTGCTGAATGAAAACGACGGCGCGAAGGGCGACGCGAACTACGTGGTGCCGGGCCTCGAACGGGGCTT
GAGAATTCTCGCGGAGTTCTCGCCGCGCGAGCCGGTGCTCGGCGCGCCGGAGCTGTCGAAGCGGCTCGGCATTCCGCGCA
CGACGGTGTTCCGGCTGCTGCAGACGCTCGAATCGCTCGGCTTTCTCGAGCGCGCGGACAAGGACCGCAACTACAAGCTC
GGCATCGCGGTGCTGCGGCTCGGCTTCGAATACCTGAGCTCGCTCGAGCTGACCGATCTCGGCCTGCCCGTGATCGAAAG
CCTGCGCGACGCGACCGGGTTCACGACGCACATCGTGATCCGCGACGGCCGCGACGTGGTGTTCGTCGCGAAGGCGCAGA
GCCAGGCGCCGGTGTTCAGCTCGATCCGGGTGAACGTTGGCACGCGGCTGCCCGCGCACGCGACCACGCACGGCCACGTG
CTGATGGGCGACCTGTCGCTGGGCGAGCTGCGCGCGCTGTATCCGGAGGGCGCGCTCAACCGGATGACGAACGCGACGCC
GGACACGGTCGATGCGTTGTACGACGTGATCCGCGAGGATGCGTTGCGCGGCTATGGCGTCAGCAACTCGTCGTTCGAGC
GCGGCATCTCGGTCGTCACCGCGCCGGTGCGCAACGACACGCAGAAGATCGTCGCGTGCATCACGGTGACGGTGCCGCGC
CCGGAGATCGACGCGGCGCTGATCGCGGACGGCCTGATCGACAAGGTGCGGCGCGCGGCGGCCGAACTGTCGCGGCGGCT
CAACTACCGCTCGGATGACGAGCATACGTTTCTGAAGGCTTTGGGGTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References