Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 1830857..1832101 Replicon chromosome
Accession NZ_CP013365
Organism Burkholderia territorii strain RF8-non-BP5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag WS51_RS08095 Protein ID WP_069228918.1
Coordinates 1831520..1832101 (+) Length 194 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag WS51_RS08090 Protein ID WP_059806086.1
Coordinates 1830857..1831414 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WS51_RS08065 1826040..1826414 + 375 WP_059506549.1 copper resistance protein CopC -
WS51_RS08070 1826481..1827194 - 714 WP_069228914.1 DUF4396 domain-containing protein -
WS51_RS08075 1827486..1828121 + 636 WP_069228915.1 cysteine hydrolase -
WS51_RS08080 1828189..1828920 - 732 WP_069228916.1 ribonuclease T2 -
WS51_RS08085 1829126..1830529 - 1404 WP_069228917.1 hypothetical protein -
WS51_RS08090 1830857..1831414 + 558 WP_059806086.1 helix-turn-helix domain-containing protein Antitoxin
WS51_RS08095 1831520..1832101 + 582 WP_069228918.1 HD domain-containing protein Toxin
WS51_RS08100 1832160..1832888 + 729 WP_069229163.1 class I SAM-dependent methyltransferase -
WS51_RS08105 1832900..1834438 - 1539 WP_069228919.1 MFS transporter -
WS51_RS08110 1834616..1835521 + 906 WP_059544211.1 LysR family transcriptional regulator -
WS51_RS08115 1835593..1836732 - 1140 WP_069228920.1 enoyl-CoA hydratase/isomerase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-168)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-61)


Sequences

Toxin        


Download         Length: 194 a.a.        Molecular weight: 21310.86 Da        Isoelectric Point: 4.8334

>T58508 WP_069228918.1 NZ_CP013365:1831520-1832101 [Burkholderia territorii]
MNLDTIHARLDFLRDAERLKDVLRSGHTSAGRAESTAEHSWRLCLMALVFADALPDVDTTKLLKLCVVHDLGEALHGDIP
AIEQAAHPDKSTHERDDLLTLTAGLDRALRDEIVALWDEYEAAASPEARAAKALDKLETILQHNQGSNPPDFDYAFNLGY
GRRYTDAAPLFVALRAIVDADTQRRIDARGSDA

Download         Length: 582 bp

>T58508 NZ_CP013365:1831520-1832101 [Burkholderia territorii]
ATGAACCTCGATACGATCCACGCGCGGCTCGATTTCCTGCGCGACGCCGAACGCCTGAAAGACGTGCTGCGCAGCGGCCA
TACGTCGGCCGGGCGCGCCGAAAGCACGGCCGAACACAGCTGGCGGCTGTGCCTGATGGCGCTCGTGTTTGCCGATGCAC
TGCCCGATGTCGATACGACGAAGCTGTTGAAGCTGTGCGTCGTCCACGATCTCGGCGAAGCGCTTCACGGCGACATCCCC
GCGATCGAGCAGGCCGCGCATCCTGACAAAAGCACACACGAACGCGACGACCTGCTGACGCTGACGGCCGGACTGGACCG
CGCGCTGCGCGACGAGATCGTCGCACTGTGGGACGAATACGAGGCGGCGGCATCGCCGGAAGCGCGCGCGGCGAAGGCGC
TCGACAAGCTCGAGACGATCCTGCAACACAACCAAGGCAGCAATCCGCCGGATTTCGACTACGCGTTCAATCTCGGCTAC
GGCCGGCGCTACACCGACGCGGCCCCGCTGTTCGTCGCGCTCCGCGCGATCGTCGATGCGGACACGCAACGCAGGATCGA
CGCACGCGGCAGCGACGCGTAA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20318.38 Da        Isoelectric Point: 11.3605

>AT58508 WP_059806086.1 NZ_CP013365:1830857-1831414 [Burkholderia territorii]
MRNSPLHTPPLGPQLKRWRTLHRVKQSHAAELFGVAQSTISRWEAGIQQMSADERAMAERLLAARLDSAGDRALARLIAG
STARMHLVCDLTHRLLACSPSRAAEFTRPLSTLVGTSLWRYASPEIVRMEAALDPLGWHDRAGPPSVEFATGANASRVVP
IRGSTCRWTRMMLSDGSAARLVETL

Download         Length: 558 bp

>AT58508 NZ_CP013365:1830857-1831414 [Burkholderia territorii]
ATGCGCAACTCACCGCTTCACACTCCGCCGCTCGGCCCGCAACTCAAGCGTTGGCGCACGCTGCATCGCGTGAAGCAGAG
CCACGCGGCCGAGTTGTTCGGCGTCGCGCAATCGACGATCTCGCGCTGGGAAGCCGGTATCCAGCAGATGTCCGCCGACG
AGCGCGCGATGGCCGAACGGTTGCTTGCCGCGCGCCTCGATTCGGCGGGCGACCGCGCGCTCGCCCGGCTGATCGCGGGC
AGCACGGCCCGCATGCATCTCGTGTGCGACCTCACGCACCGTCTGCTCGCCTGCTCGCCGTCGCGCGCGGCCGAGTTCAC
GCGGCCGCTGTCGACATTGGTCGGCACGTCGCTCTGGCGGTACGCGTCGCCGGAGATCGTCCGCATGGAAGCCGCGCTCG
ACCCGCTCGGCTGGCACGATCGCGCGGGACCGCCGAGCGTCGAATTCGCGACCGGCGCCAATGCGTCGCGCGTCGTGCCG
ATCCGCGGCAGCACCTGCCGATGGACGCGGATGATGCTGTCGGACGGCTCCGCCGCGCGGCTCGTCGAAACGCTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References