Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1680094..1680749 Replicon chromosome
Accession NZ_CP013365
Organism Burkholderia territorii strain RF8-non-BP5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag WS51_RS07385 Protein ID WP_069228872.1
Coordinates 1680094..1680513 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag WS51_RS07390 Protein ID WP_059506772.1
Coordinates 1680510..1680749 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WS51_RS07360 1675635..1676429 + 795 WP_069228871.1 AraC family transcriptional regulator -
WS51_RS07365 1676633..1677556 + 924 WP_069229157.1 DMT family transporter -
WS51_RS07370 1677688..1678236 + 549 WP_059506731.1 hypothetical protein -
WS51_RS07375 1678327..1678461 - 135 WP_059449563.1 entericidin A/B family lipoprotein -
WS51_RS07380 1678694..1679989 + 1296 WP_059449562.1 aspartate carbamoyltransferase -
WS51_RS07385 1680094..1680513 - 420 WP_069228872.1 type II toxin-antitoxin system VapC family toxin Toxin
WS51_RS07390 1680510..1680749 - 240 WP_059506772.1 hypothetical protein Antitoxin
WS51_RS07395 1681071..1683314 + 2244 WP_069228873.1 TonB-dependent siderophore receptor -
WS51_RS07400 1683318..1684073 + 756 WP_069228874.1 sel1 repeat family protein -
WS51_RS07405 1684070..1684753 + 684 WP_059544061.1 Fe2+-dependent dioxygenase -
WS51_RS07410 1685110..1685694 + 585 WP_059506727.1 nucleotidyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14881.23 Da        Isoelectric Point: 5.1832

>T58507 WP_069228872.1 NZ_CP013365:c1680513-1680094 [Burkholderia territorii]
MILVDTNVISEPLRREPSGAVIEWLDAQIVETLFLSAISLAEMRFGVAALPAGRRRDWLDQSIEQRVLPLFRGRILPFDD
AASKAYASLRAKARAAGLALVPADGFIAATAAANGLIVATRDVAPFEAAGLRVIDPWAG

Download         Length: 420 bp

>T58507 NZ_CP013365:c1680513-1680094 [Burkholderia territorii]
ATGATCCTGGTCGATACCAACGTCATTTCCGAGCCGTTGCGGCGCGAGCCGAGCGGGGCGGTGATCGAATGGCTCGACGC
GCAGATCGTCGAGACGTTGTTTCTTTCCGCGATCAGTCTCGCGGAAATGCGATTCGGCGTGGCAGCGTTGCCGGCAGGGC
GCAGGCGGGACTGGCTGGACCAAAGCATCGAGCAGCGCGTCCTGCCGCTGTTTCGCGGCCGGATCCTGCCGTTCGACGAT
GCCGCCAGCAAGGCGTATGCGAGCCTTCGCGCGAAGGCTCGTGCGGCAGGCCTCGCGCTGGTACCGGCCGATGGTTTTAT
CGCCGCGACGGCCGCGGCGAACGGCTTGATCGTCGCCACGCGCGACGTCGCGCCGTTCGAAGCGGCAGGCCTGCGCGTGA
TCGATCCGTGGGCCGGCTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8910.03 Da        Isoelectric Point: 6.4704

>AT58507 WP_059506772.1 NZ_CP013365:c1680749-1680510 [Burkholderia territorii]
MAVITVRNLSDEVHRALRIRAAQHGRSTEAEVRDILEQAVRPDGRPRLGTLLAEIGREAGGIDFEIQRDRSRTDPMSFE

Download         Length: 240 bp

>AT58507 NZ_CP013365:c1680749-1680510 [Burkholderia territorii]
ATGGCCGTGATCACAGTTCGAAATTTGTCCGACGAGGTGCATCGCGCGCTTCGAATCCGTGCGGCGCAACATGGCCGCAG
CACCGAAGCCGAGGTGCGCGACATTCTGGAGCAGGCCGTCCGGCCAGACGGGCGGCCGAGGCTCGGAACGTTGTTGGCCG
AGATCGGGCGGGAGGCCGGCGGTATCGATTTCGAGATTCAGCGCGACAGATCGCGCACCGATCCGATGAGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References