Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1532351..1534104 Replicon chromosome
Accession NZ_CP013365
Organism Burkholderia territorii strain RF8-non-BP5

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag WS51_RS06780 Protein ID WP_059451072.1
Coordinates 1533208..1534104 (-) Length 299 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag WS51_RS06775 Protein ID WP_059507653.1
Coordinates 1532351..1533211 (-) Length 287 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WS51_RS06755 1527411..1528901 - 1491 WP_069228838.1 aldehyde dehydrogenase -
WS51_RS06760 1528991..1529818 - 828 WP_069228839.1 aspartate dehydrogenase -
WS51_RS06765 1529811..1531481 - 1671 WP_059451075.1 thiamine pyrophosphate-binding protein -
WS51_RS06770 1531474..1532271 - 798 WP_059507652.1 SDR family oxidoreductase -
WS51_RS06775 1532351..1533211 - 861 WP_059507653.1 IclR family transcriptional regulator Antitoxin
WS51_RS06780 1533208..1534104 - 897 WP_059451072.1 alpha/beta fold hydrolase Toxin
WS51_RS06785 1534123..1534650 - 528 WP_009692519.1 cupin domain-containing protein -
WS51_RS06790 1534685..1535455 - 771 WP_059451071.1 SDR family oxidoreductase -
WS51_RS06795 1535448..1536518 - 1071 WP_059451070.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
WS51_RS06800 1536573..1536884 - 312 WP_039321045.1 hypothetical protein -
WS51_RS06805 1536886..1537203 - 318 WP_006758060.1 non-heme iron oxygenase ferredoxin subunit -
WS51_RS06810 1537654..1538733 + 1080 WP_059451069.1 porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(51-279)

Antitoxin

Transcription regulator IclR, N-terminal

(25-73)


Sequences

Toxin        


Download         Length: 299 a.a.        Molecular weight: 30793.98 Da        Isoelectric Point: 7.7327

>T58506 WP_059451072.1 NZ_CP013365:c1534104-1533208 [Burkholderia territorii]
MSVIDKRERDRTAAFAALLGQFPEQRCAAGAAGTIGYREAGAQHAGRALPVVLLHGIGSGAASWVRQLDTLGASRRVLAW
DAPGYGVSTPVHGASPTAADYAASLNAWLEALGIERCVLVGHSLGAIVAGGLARAMPARIAGLLLISPAGGYGSAPAETR
DARRDARLAMLEELGPAGLAEQRSANMLSGFASEDARAWVRWNMARIVPAGYAQATHLLANADLASDLAGFRGRTAVAVG
ANDAITPPAACERIAAAAHVGLQVIPQAGHAGYVEAPAVYSSLIDTFCRQCDRQRGLE

Download         Length: 897 bp

>T58506 NZ_CP013365:c1534104-1533208 [Burkholderia territorii]
ATGAGTGTCATCGACAAACGTGAACGCGACCGCACGGCGGCGTTCGCCGCGCTGCTCGGGCAGTTTCCCGAACAGCGCTG
CGCGGCCGGCGCGGCGGGCACGATCGGCTATCGCGAGGCCGGCGCGCAGCATGCGGGCCGCGCGTTGCCCGTCGTGCTGC
TGCACGGGATCGGCTCGGGCGCCGCATCGTGGGTGCGCCAGCTCGACACGCTCGGTGCGTCGCGACGCGTGCTGGCGTGG
GACGCGCCCGGCTACGGTGTGTCGACCCCCGTGCACGGCGCGTCGCCGACGGCCGCCGATTACGCGGCGTCGCTGAACGC
GTGGCTCGAGGCACTCGGCATCGAACGCTGCGTGCTGGTCGGGCATTCGCTCGGTGCGATCGTCGCGGGCGGGTTGGCCC
GCGCGATGCCCGCGCGGATCGCCGGCCTGCTGCTGATCTCGCCCGCGGGCGGTTACGGCAGCGCGCCCGCCGAAACGCGC
GACGCACGCCGCGATGCGCGCCTCGCGATGCTCGAGGAACTCGGCCCGGCCGGGCTCGCCGAGCAGCGCAGCGCCAACAT
GCTGTCGGGTTTCGCGAGCGAGGATGCGCGTGCGTGGGTGCGCTGGAACATGGCGCGCATCGTGCCGGCCGGCTATGCGC
AGGCCACGCACCTGCTCGCGAATGCCGATCTCGCGTCCGATCTCGCCGGCTTTCGCGGTCGGACCGCGGTGGCGGTCGGC
GCGAACGACGCGATCACGCCGCCTGCGGCGTGCGAGCGGATCGCCGCGGCAGCGCACGTCGGGCTGCAAGTGATTCCGCA
GGCCGGTCACGCGGGTTACGTGGAAGCACCGGCGGTTTATTCGTCACTGATCGACACGTTCTGCCGTCAATGCGATCGTC
AACGGGGGCTGGAATGA

Antitoxin


Download         Length: 287 a.a.        Molecular weight: 31597.13 Da        Isoelectric Point: 6.6563

>AT58506 WP_059507653.1 NZ_CP013365:c1533211-1532351 [Burkholderia territorii]
MSEPLQQRQDAEVAKSDANYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNY
KLGIAVLRLGFEYLSSLELTDLGLPVIESLRDATGFTTHIVIRDGRDVVFVAKAQSQSPVFSSIRVNVGTRLPAHATTHG
HVLMGDLSLKELRDLYPESTLNRMTSATPETVDALYEVIREDALRGYGVSNSSFERGISVVTAPVRNDTQKIVACITVTV
PRPEIDAALIADGLIDKVQRAAAELSRRLNYRSDDEHTFMKALGLK

Download         Length: 861 bp

>AT58506 NZ_CP013365:c1533211-1532351 [Burkholderia territorii]
ATGAGCGAACCGTTGCAACAGCGGCAGGACGCGGAAGTCGCGAAGTCCGACGCGAACTACGTGGTGCCGGGCCTCGAACG
CGGCCTGCGCATCCTCGCGGAGTTCTCGCCGCGCGAGCCGGTACTGGGCGCGCCGGAGTTGTCGAAGCGGCTCGGCATTC
CGCGCACGACGGTGTTTCGTCTGCTGCAGACGCTCGAGTCGCTGGGCTTTCTCGAGCGCGCGGACAAGGACCGCAACTAC
AAGCTAGGCATCGCCGTGCTGCGACTCGGCTTCGAATACCTGAGCTCGCTCGAGCTGACCGATCTCGGCCTGCCGGTGAT
CGAAAGCCTGCGCGACGCGACCGGTTTCACGACGCACATCGTGATCCGCGACGGCCGCGACGTGGTGTTCGTCGCGAAGG
CGCAGAGCCAGTCGCCGGTGTTCAGCTCGATTCGCGTGAACGTCGGCACGCGGCTGCCCGCGCATGCGACGACGCACGGC
CACGTGCTGATGGGCGACCTGTCGCTGAAGGAATTGCGCGATCTGTATCCGGAAAGCACGCTGAACCGGATGACGAGCGC
GACGCCGGAGACAGTCGATGCGTTGTACGAAGTAATCCGCGAGGACGCATTGCGCGGCTACGGCGTCAGCAATTCGTCGT
TCGAACGCGGCATTTCGGTGGTCACGGCGCCGGTGCGCAACGACACGCAGAAGATCGTCGCGTGCATCACGGTGACGGTG
CCTCGGCCGGAGATCGACGCGGCGCTGATCGCCGACGGCCTGATCGACAAGGTGCAGCGCGCGGCGGCGGAACTGTCGCG
GCGGCTCAATTACCGCTCGGACGACGAGCACACGTTTATGAAGGCTTTGGGATTGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References