Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 508533..509173 Replicon chromosome
Accession NZ_CP013365
Organism Burkholderia territorii strain RF8-non-BP5

Toxin (Protein)


Gene name relE Uniprot ID A0A104DPZ6
Locus tag WS51_RS02400 Protein ID WP_059466579.1
Coordinates 508835..509173 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag WS51_RS02395 Protein ID WP_006750245.1
Coordinates 508533..508832 (-) Length 100 a.a.

Genomic Context

WS51_RS02370WS51_RS02375WS51_RS02380WS51_RS02385WS51_RS02390WS51_RS02405WS51_RS02410WS51_RS02365WS51_RS02395WS51_RS02400
Location: 504663..505613 (951 bp)
Type: Others
Protein ID: WP_069228543.1
Location: 505610..506002 (393 bp)
Type: Others
Protein ID: WP_059503681.1
Location: 506005..506463 (459 bp)
Type: Others
Protein ID: WP_059504048.1
Location: 506463..507674 (1212 bp)
Type: Others
Protein ID: WP_060361628.1
Location: 507682..508515 (834 bp)
Type: Others
Protein ID: WP_059503677.1
Location: 509538..511178 (1641 bp)
Type: Others
Protein ID: WP_059503675.1
Location: 511207..512640 (1434 bp)
Type: Others
Protein ID: WP_069228544.1
Location: 503661..504566 (906 bp)
Type: Others
Protein ID: WP_059448774.1
Location: 508533..508832 (300 bp)
Type: Antitoxin
Protein ID: WP_006750245.1
Location: 508835..509173 (339 bp)
Type: Toxin
Protein ID: WP_059466579.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
WS51_RS02365503661..504566-906WP_059448774.1LysR family transcriptional regulator-
WS51_RS02370504663..505613+951WP_069228543.1ketopantoate reductase family protein-
WS51_RS02375505610..506002+393WP_059503681.1VOC family protein-
WS51_RS02380506005..506463+459WP_059504048.1MaoC family dehydratase-
WS51_RS02385506463..507674+1212WP_060361628.1CoA transferase-
WS51_RS02390507682..508515+834WP_059503677.1shikimate dehydrogenase-
WS51_RS02395508533..508832-300WP_006750245.1putative addiction module antidote proteinAntitoxin
WS51_RS02400508835..509173-339WP_059466579.1type II toxin-antitoxin system RelE/ParE family toxinToxin
WS51_RS02405509538..511178+1641WP_059503675.1acetolactate synthase large subunit-
WS51_RS02410511207..512640+1434WP_069228544.1aldehyde dehydrogenase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(26-103)

Antitoxin

Uncharacterized protein HI1420

(5-93)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12715.57 Da        Isoelectric Point: 8.9562

>T58505 WP_059466579.1 NZ_CP013365:c509173-508835 [Burkholderia territorii]
MVDTLPFMPYSAPTFSIRTTDVFDAWFAGLQDRVARRRIQARIDRLSMGNPGDWKSAGSPVVEMRVDHGPGYRVYYVRRG
TIWVILLCGGDKSTQQADIRAAHAMLERLDLE

Download         Length: 339 bp

>T58505 NZ_CP013365:c509173-508835 [Burkholderia territorii]
ATGGTTGACACATTGCCATTCATGCCCTACAGTGCGCCTACATTCAGTATCCGGACCACCGACGTCTTCGATGCATGGTT
TGCCGGCCTGCAGGATCGCGTCGCGCGGCGGCGCATCCAGGCACGCATCGATCGTCTGTCGATGGGCAACCCGGGCGACT
GGAAATCCGCCGGCTCGCCCGTCGTCGAAATGCGTGTCGACCACGGCCCCGGCTATCGCGTCTATTACGTCAGACGCGGA
ACGATTTGGGTGATCCTGCTCTGCGGCGGCGACAAGTCGACGCAACAGGCGGACATCCGCGCCGCGCACGCGATGCTCGA
GCGGCTCGACCTGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10674.11 Da        Isoelectric Point: 6.6384

>AT58505 WP_006750245.1 NZ_CP013365:c508832-508533 [Burkholderia territorii]
MDKIKTRPWDSAEHLKTDDDMADYFEACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKAHA

Download         Length: 300 bp

>AT58505 NZ_CP013365:c508832-508533 [Burkholderia territorii]
ATGGACAAGATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTGAAGACCGACGACGACATGGCCGACTACTTCGAGGC
CTGTCTGCAGGAAGCCGGCGACGATCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGTGCGCGCGGCATGTCGC
AGGTCGCGCGCGACGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGTTTCGGCACG
ATCCTGAAGGTGATCAAGGCACTCGGCCTCCAACTGCACGGCGCGAAGGCGCATGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A104DPZ6

Antitoxin

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Source
ID
Structure
No matching records found

References