Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-StbC
Location 1677188..1677848 Replicon chromosome
Accession NZ_CP013347
Organism Paraburkholderia caribensis strain Bcrs1W

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ATN79_RS07410 Protein ID WP_082434037.1
Coordinates 1677420..1677848 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ATN79_RS07405 Protein ID WP_062915861.1
Coordinates 1677188..1677433 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ATN79_RS07380 1672781..1673293 - 513 WP_035990992.1 Spy/CpxP family protein refolding chaperone -
ATN79_RS07385 1673446..1674330 + 885 WP_062915294.1 LysR family transcriptional regulator -
ATN79_RS07390 1674467..1674931 + 465 WP_035990996.1 Lrp/AsnC family transcriptional regulator -
ATN79_RS07395 1675139..1676236 + 1098 WP_035990998.1 saccharopine dehydrogenase NADP-binding domain-containing protein -
ATN79_RS07400 1676398..1677018 - 621 WP_062915295.1 ATP-binding protein -
ATN79_RS07405 1677188..1677433 + 246 WP_062915861.1 hypothetical protein Antitoxin
ATN79_RS07410 1677420..1677848 + 429 WP_082434037.1 type II toxin-antitoxin system VapC family toxin Toxin
ATN79_RS07415 1677937..1678410 + 474 WP_082845362.1 hypothetical protein -
ATN79_RS07420 1678615..1679592 + 978 WP_054934556.1 magnesium/cobalt transporter CorA -
ATN79_RS07425 1679633..1680271 - 639 WP_062915296.1 LysE family translocator -
ATN79_RS07430 1680822..1681778 + 957 WP_054934558.1 sugar ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15715.91 Da        Isoelectric Point: 7.4682

>T58484 WP_082434037.1 NZ_CP013347:1677420-1677848 [Paraburkholderia caribensis]
VYLIDTNVISEMRKSSRANPGVQAFFETAKEGGHRLYLSVVTVGELRRGVDLIRHRGDKFQALRLEGWLDTIMNSFSSHI
LNVGTDVAQTWGHLRVPDPGHSLDKLIAATALIYNLTVVTRNVADFDGTGARVLNPFQLLDA

Download         Length: 429 bp

>T58484 NZ_CP013347:1677420-1677848 [Paraburkholderia caribensis]
GTGTATTTGATTGATACCAATGTAATCAGCGAAATGCGCAAGAGCAGCCGCGCCAATCCGGGCGTACAGGCTTTTTTCGA
AACGGCGAAGGAAGGCGGGCATCGCCTGTATCTGTCTGTGGTGACGGTTGGCGAGTTGCGGCGCGGCGTCGACCTGATCC
GGCATCGGGGCGACAAGTTCCAGGCATTGCGCCTGGAAGGCTGGCTCGACACGATCATGAATTCGTTCAGCAGCCACATC
TTGAATGTCGGCACCGACGTTGCGCAGACGTGGGGCCATCTGCGCGTGCCCGACCCCGGGCATTCGCTGGACAAACTGAT
CGCGGCCACGGCCCTGATCTACAACCTGACTGTCGTGACGCGCAACGTGGCAGACTTCGATGGCACGGGCGCACGGGTGC
TCAATCCGTTCCAGCTTCTCGACGCATGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8966.95 Da        Isoelectric Point: 4.3393

>AT58484 WP_062915861.1 NZ_CP013347:1677188-1677433 [Paraburkholderia caribensis]
MANLLVRNLDDALVQNLREQAAAHGRSVEAEHREILAQALFRPRKLSFAELLMSMPDVGDDADFERRNDATDDSGGPGVF
D

Download         Length: 246 bp

>AT58484 NZ_CP013347:1677188-1677433 [Paraburkholderia caribensis]
ATGGCAAATCTTTTGGTCCGAAATCTGGACGATGCGTTGGTGCAGAACCTGCGTGAGCAGGCCGCGGCTCACGGGCGCAG
CGTCGAAGCAGAGCATCGGGAAATCCTGGCGCAGGCGCTCTTTCGGCCCAGGAAGCTCAGCTTTGCGGAATTGCTGATGA
GCATGCCCGACGTCGGCGACGACGCCGACTTCGAGCGCCGCAATGACGCAACTGACGATAGCGGGGGACCGGGTGTATTT
GATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References