Detailed information of TA system TA058470

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 2453445..2454358
• Replicon: chromosome
• Accession: NZ_CP013338
• Organism: Raoultella ornithinolytica strain Yangling I2

Toxin (Protein)

• Gene name: -
• Uniprot ID: A0A808Y4A8
• Locus tag: ATN83_RS11375
• Protein ID: WP_015584188.1
• Coordinates: 2453445..2453918 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A808Y7A4
• Locus tag: ATN83_RS11380
• Protein ID: WP_004862777.1
• Coordinates: 2453915..2454358 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ATN83_RS11350	2449484..2450092	-	609	WP_032724246.1	glutathione S-transferase family protein	-
ATN83_RS11355	2450334..2451239	+	906	WP_032716408.1	transcriptional regulator GcvA	-
ATN83_RS11360	2451267..2452172	-	906	WP_044349852.1	LysR family transcriptional regulator	-
ATN83_RS11365	2452275..2452592	+	318	WP_004862785.1	nuclear transport factor 2 family protein	-
ATN83_RS11370	2452585..2453364	+	780	WP_004862782.1	SDR family oxidoreductase	-
ATN83_RS11375	2453445..2453918	-	474	WP_015584188.1	RES domain-containing protein	Toxin
ATN83_RS11380	2453915..2454358	-	444	WP_004862777.1	DUF2384 domain-containing protein	Antitoxin
ATN83_RS11385	2454548..2455114	-	567	WP_015584190.1	DJ-1/PfpI family protein	-
ATN83_RS11390	2455512..2456294	+	783	WP_064356988.1	DUF3750 domain-containing protein	-
ATN83_RS11395	2456489..2457712	+	1224	WP_004862767.1	zinc metallochaperone GTPase ZigA	-
ATN83_RS27420	2458642..2459118	-	477	WP_071887178.1	acid resistance repetitive basic protein Asr	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-148)

Antitoxin

• Antitoxin Xre (15-147)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17524.82 Da
• Isoelectric Point: 4.8081

>T58470 WP_015584188.1 NZ_CP013338:c2453918-2453445 [Raoultella ornithinolytica]
MIFYRLVTGRYASEAWTGSGANQYGGRWNHQGHPAVYVSTSIALASLEILVHVKNEAILNQYQLYSIEIPDSEVESLDKQ
WLPDNWQENPMPVSTMDLGTGWLQSGSGLALMLPSCIIPYENNAILNPLHPAFSEALASVRQYPFTFDPRLARSTPL

Nucleotide

• Length: 474 bp

>T58470 NZ_CP013338:c2453918-2453445 [Raoultella ornithinolytica]
ATGATTTTCTATCGTCTGGTTACCGGCCGTTACGCCAGCGAAGCCTGGACGGGAAGCGGGGCCAACCAGTACGGCGGGCG
CTGGAATCACCAGGGACACCCGGCGGTCTATGTGTCCACTTCCATTGCCCTGGCGTCACTGGAGATCCTGGTTCACGTCA
AAAATGAGGCAATCCTCAACCAGTATCAGCTGTATAGTATCGAGATACCGGACAGCGAAGTGGAATCCCTCGATAAACAG
TGGTTACCGGATAACTGGCAAGAAAATCCGATGCCCGTTTCCACAATGGATCTGGGCACCGGCTGGCTACAGTCGGGCAG
CGGTCTGGCGCTGATGCTTCCCTCCTGCATTATTCCCTATGAAAACAACGCCATTTTAAACCCGCTGCATCCCGCGTTCA
GCGAGGCCCTGGCCTCCGTGCGTCAGTATCCCTTTACCTTTGATCCCCGCCTCGCACGCTCCACGCCCCTCTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16190.45 Da
• Isoelectric Point: 4.9405

>AT58470 WP_004862777.1 NZ_CP013338:c2454358-2453915 [Raoultella ornithinolytica]
MKTWVPAEQPADNALWRYAGLPANRGMQLIELLSMGLPVSILDNIHEWTEMSKTDILRITGINERNVARRKSAGGTLTPG
ESERVARFVRVLDTAVDYFGSKQDAYDWLQSPVRGLGNVAPIDLIATESGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT58470 NZ_CP013338:c2454358-2453915 [Raoultella ornithinolytica]
ATGAAAACCTGGGTTCCTGCAGAGCAACCTGCCGATAATGCGCTGTGGCGCTATGCCGGGCTACCGGCGAATCGGGGTAT
GCAGTTGATTGAGCTGCTGAGTATGGGATTACCGGTCAGCATTCTGGATAATATTCATGAGTGGACGGAAATGTCGAAAA
CCGACATTCTGCGCATCACCGGGATTAATGAGCGCAACGTTGCCCGGCGCAAGAGCGCGGGCGGCACGTTGACGCCAGGC
GAAAGCGAACGTGTGGCGCGTTTTGTCAGGGTCCTGGATACCGCCGTCGACTATTTTGGCAGCAAGCAGGATGCCTACGA
CTGGCTGCAGTCGCCGGTCAGAGGACTGGGCAATGTCGCCCCCATCGATCTGATTGCTACCGAGAGCGGCGCGCTGGAAG
TAACAGACCTGATTGGTCGCCTGGAACACGGCGTCTTTGCATGA

Structures

Toxin

• AlphaFold DB: A0A808Y4A8

Antitoxin

• AlphaFold DB: A0A808Y7A4