Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1797970..1798484 Replicon chromosome
Accession NZ_CP013334
Organism Fusobacterium hwasookii ChDC F300

Toxin (Protein)


Gene name relB Uniprot ID X7SD51
Locus tag RN97_RS08770 Protein ID WP_005919455.1
Coordinates 1797970..1798227 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID U7TQU0
Locus tag RN97_RS08775 Protein ID WP_005919458.1
Coordinates 1798227..1798484 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RN97_RS12780 1793437..1794354 - 918 Protein_1755 hypothetical protein -
RN97_RS08750 1794444..1795006 - 563 Protein_1756 hypothetical protein -
RN97_RS08755 1795003..1795486 - 484 Protein_1757 hypothetical protein -
RN97_RS08760 1795807..1796544 - 738 WP_029490882.1 tRNA pseudouridine(38-40) synthase TruA -
RN97_RS08765 1796777..1797853 - 1077 WP_029490883.1 DHH family phosphoesterase -
RN97_RS08770 1797970..1798227 - 258 WP_005919455.1 Txe/YoeB family addiction module toxin Toxin
RN97_RS08775 1798227..1798484 - 258 WP_005919458.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
RN97_RS08780 1798604..1799677 - 1074 WP_029490884.1 glycerophosphodiester phosphodiesterase -
RN97_RS08785 1799721..1800719 - 999 WP_029490885.1 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase -
RN97_RS08790 1800744..1801217 - 474 WP_029490886.1 OmpH family outer membrane protein -
RN97_RS08795 1801257..1803350 - 2094 WP_029490887.1 outer membrane protein assembly factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10159.71 Da        Isoelectric Point: 9.7287

>T58458 WP_005919455.1 NZ_CP013334:c1798227-1797970 [Fusobacterium hwasookii ChDC F300]
MLLTWTDFAWKQYEELQEKDKRLIKKINILIKDIKRNGNEGIGKPEPLQHELSGYWSRRIDDKNRLVYKVSDNQITIVAC
ANHYK

Download         Length: 258 bp

>T58458 NZ_CP013334:c1798227-1797970 [Fusobacterium hwasookii ChDC F300]
ATGTTATTAACTTGGACCGATTTTGCATGGAAACAATATGAAGAGCTACAAGAGAAGGATAAAAGGCTTATAAAGAAGAT
AAATATACTTATTAAGGATATAAAAAGAAATGGAAATGAAGGAATAGGTAAACCAGAGCCTTTACAACATGAGTTAAGTG
GCTATTGGAGTAGAAGAATTGATGATAAAAATAGATTAGTCTATAAAGTATCAGATAATCAAATAACAATAGTTGCTTGT
GCAAATCATTATAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10110.43 Da        Isoelectric Point: 4.7022

>AT58458 WP_005919458.1 NZ_CP013334:c1798484-1798227 [Fusobacterium hwasookii ChDC F300]
MIATNYSEVRNNLKAYCDKATKDYETIIITRKNNENVVLMSEEEYNNLMENLYIRSNLKYYQKLVESIKEVEKGNVKEHD
LIEVD

Download         Length: 258 bp

>AT58458 NZ_CP013334:c1798484-1798227 [Fusobacterium hwasookii ChDC F300]
ATGATAGCAACTAATTATTCTGAAGTTAGAAATAATTTAAAAGCTTATTGTGATAAGGCAACTAAGGACTATGAAACTAT
CATTATTACAAGAAAAAATAATGAAAATGTTGTCTTAATGAGTGAAGAAGAATATAATAATCTTATGGAAAACCTTTATA
TAAGATCAAATCTTAAATATTATCAAAAACTTGTAGAAAGTATAAAAGAAGTTGAAAAAGGTAATGTTAAAGAACATGAT
TTAATAGAGGTGGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0S2ZLL4

Antitoxin

Source ID Structure
AlphaFold DB A0A0S2ZLE4

References