Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4161488..4161633 Replicon chromosome
Accession NZ_CP013322
Organism Klebsiella pneumoniae strain CAV1193

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4161524..4161626 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4161488..4161633 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AGG09_RS20625 4156618..4158678 + 2061 WP_040213005.1 oligopeptidase B -
AGG09_RS20630 4158682..4159341 - 660 WP_021440386.1 exodeoxyribonuclease X -
AGG09_RS20635 4159420..4159650 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AGG09_RS20640 4159763..4160137 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AGG09_RS20645 4160141..4161010 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
AGG09_RS20650 4161027..4161365 + 339 WP_002911404.1 YebY family protein -
- 4161488..4161633 - 146 - - Antitoxin
- 4161524..4161626 + 103 - - Toxin
AGG09_RS32530 4162001..4162144 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AGG09_RS20660 4162249..4163217 - 969 WP_004151446.1 VirK/YbjX family protein -
AGG09_RS20665 4163374..4164027 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
AGG09_RS20670 4164024..4164215 - 192 WP_002911395.1 YebW family protein -
AGG09_RS20675 4164313..4164552 - 240 WP_002911393.1 YebV family protein -
AGG09_RS20680 4164668..4166101 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T58440 NZ_CP013322:4161524-4161626 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT58440 NZ_CP013322:c4161633-4161488 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References