Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /SpoIISA(toxin) |
| Location | 2312557..2313535 | Replicon | chromosome |
| Accession | NZ_CP013275 | ||
| Organism | Bacillus thuringiensis serovar israelensis strain AM65-52 | ||
Toxin (Protein)
| Gene name | spoIISA | Uniprot ID | - |
| Locus tag | ATN07_RS12070 | Protein ID | WP_000624969.1 |
| Coordinates | 2312557..2313294 (+) | Length | 246 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | B7IX39 |
| Locus tag | ATN07_RS12075 | Protein ID | WP_000237817.1 |
| Coordinates | 2313407..2313535 (+) | Length | 43 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ATN07_RS12040 | 2308148..2308555 | + | 408 | WP_000072495.1 | VOC family protein | - |
| ATN07_RS12045 | 2308900..2309682 | + | 783 | WP_000381785.1 | class I SAM-dependent methyltransferase | - |
| ATN07_RS12050 | 2309836..2310660 | - | 825 | WP_014895244.1 | alpha-keto acid decarboxylase family protein | - |
| ATN07_RS12055 | 2310657..2310785 | - | 129 | WP_003265031.1 | hypothetical protein | - |
| ATN07_RS12060 | 2310933..2311415 | + | 483 | WP_000191905.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| ATN07_RS12065 | 2311581..2312318 | + | 738 | WP_000594159.1 | 2,3-diphosphoglycerate-dependent phosphoglycerate mutase | - |
| ATN07_RS12070 | 2312557..2313294 | + | 738 | WP_000624969.1 | type II toxin-antitoxin system SpoIISA family toxin | Toxin |
| ATN07_RS12075 | 2313407..2313535 | + | 129 | WP_000237817.1 | hypothetical protein | Antitoxin |
| ATN07_RS12080 | 2313608..2313784 | + | 177 | WP_000852629.1 | stage II sporulation protein SB | - |
| ATN07_RS12085 | 2313803..2314192 | - | 390 | WP_000712655.1 | YxeA family protein | - |
| ATN07_RS12090 | 2314404..2315873 | + | 1470 | WP_000287541.1 | beta-Ala-His dipeptidase | - |
| ATN07_RS12095 | 2316186..2316995 | + | 810 | WP_000678376.1 | C39 family peptidase | - |
| ATN07_RS12100 | 2317021..2317626 | + | 606 | WP_000527414.1 | hypothetical protein | - |
| ATN07_RS12105 | 2317767..2318018 | - | 252 | WP_000821942.1 | response regulator transcription factor | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 246 a.a. Molecular weight: 28383.13 Da Isoelectric Point: 8.2998
>T58207 WP_000624969.1 NZ_CP013275:2312557-2313294 [Bacillus thuringiensis serovar israelensis]
MISNIRIGLFVLAIFFVVLVFFYWKNEELYEEKKQRIRKTWYGLFIISVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYTKSLNVFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSIIVPLEHIEQLNEQKAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK
MISNIRIGLFVLAIFFVVLVFFYWKNEELYEEKKQRIRKTWYGLFIISVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYTKSLNVFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSIIVPLEHIEQLNEQKAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK
Download Length: 738 bp
>T58207 NZ_CP013275:2312557-2313294 [Bacillus thuringiensis serovar israelensis]
ATGATCTCTAACATTCGAATTGGCTTATTTGTTTTAGCGATTTTCTTTGTAGTCCTTGTTTTCTTTTATTGGAAAAATGA
GGAGTTGTACGAGGAGAAAAAGCAACGTATTAGAAAGACTTGGTATGGTTTGTTTATCATATCTGTCACCGTGTATTTCA
TGATAAAAGGAATTGATTTAACCCTCTGGAAAAATCTTTTAATGTTTACTGCAATGGTTATTTTTGTTGATATTGCGTTC
ATTTTAACGCCTAATATTTCAGAAATATGGGGTGCGAAATTTAGCGATATTGGCAAGACAGTTCAATCAATAAAACGATC
ATTAATTGCATCTAAAGCGAGAGGAGAAATATACACCACAATTATTCAAAATGTTAATCCAGCAGTTTTCGGTACGATGG
AATGGCATACGGAAGAAGAATATACAAAGAGCTTAAATGTATTTTTAGATTCATATGGGGAAAAAATTGGCGCGAAAATT
GTTGTTTTTGAAGCGGCAAAGGAATTAAATACAAACTTTCGTGGTATTCGCTCGCAATTTAGTATTATCGTTCCGTTAGA
ACATATCGAGCAATTGAATGAGCAGAAAGCAGTGCAAGTAGAAAATGTCGGGATTATACCAGCAAAAATAGTAAGTGATG
TTTTCATTGTTATTGATGGAAAGAAAAATAACCTGCAAGATCGGGATTTTGAAAATGTATATAATTTAACAATACATCAT
AGTTATTTTAGTAAATAA
ATGATCTCTAACATTCGAATTGGCTTATTTGTTTTAGCGATTTTCTTTGTAGTCCTTGTTTTCTTTTATTGGAAAAATGA
GGAGTTGTACGAGGAGAAAAAGCAACGTATTAGAAAGACTTGGTATGGTTTGTTTATCATATCTGTCACCGTGTATTTCA
TGATAAAAGGAATTGATTTAACCCTCTGGAAAAATCTTTTAATGTTTACTGCAATGGTTATTTTTGTTGATATTGCGTTC
ATTTTAACGCCTAATATTTCAGAAATATGGGGTGCGAAATTTAGCGATATTGGCAAGACAGTTCAATCAATAAAACGATC
ATTAATTGCATCTAAAGCGAGAGGAGAAATATACACCACAATTATTCAAAATGTTAATCCAGCAGTTTTCGGTACGATGG
AATGGCATACGGAAGAAGAATATACAAAGAGCTTAAATGTATTTTTAGATTCATATGGGGAAAAAATTGGCGCGAAAATT
GTTGTTTTTGAAGCGGCAAAGGAATTAAATACAAACTTTCGTGGTATTCGCTCGCAATTTAGTATTATCGTTCCGTTAGA
ACATATCGAGCAATTGAATGAGCAGAAAGCAGTGCAAGTAGAAAATGTCGGGATTATACCAGCAAAAATAGTAAGTGATG
TTTTCATTGTTATTGATGGAAAGAAAAATAACCTGCAAGATCGGGATTTTGAAAATGTATATAATTTAACAATACATCAT
AGTTATTTTAGTAAATAA
Antitoxin
Download Length: 43 a.a. Molecular weight: 4981.37 Da Isoelectric Point: 3.9150
>AT58207 WP_000237817.1 NZ_CP013275:2313407-2313535 [Bacillus thuringiensis serovar israelensis]
VVKDYDNDFFKEDNEDTTDFSLIKGDALQQVEELEEELKRKS
VVKDYDNDFFKEDNEDTTDFSLIKGDALQQVEELEEELKRKS
Download Length: 129 bp
>AT58207 NZ_CP013275:2313407-2313535 [Bacillus thuringiensis serovar israelensis]
GTGGTAAAAGATTATGACAATGATTTTTTTAAAGAAGATAACGAAGATACAACAGATTTCTCTTTAATAAAAGGGGATGC
GTTGCAGCAAGTAGAAGAATTAGAAGAAGAATTAAAAAGAAAATCATAA
GTGGTAAAAGATTATGACAATGATTTTTTTAAAGAAGATAACGAAGATACAACAGATTTCTCTTTAATAAAAGGGGATGC
GTTGCAGCAAGTAGAAGAATTAGAAGAAGAATTAAAAAGAAAATCATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|