Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2348395..2349370 Replicon chromosome
Accession NZ_CP013274
Organism Bacillus thuringiensis strain CTC

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag ATN06_RS12270 Protein ID WP_060633134.1
Coordinates 2348395..2349132 (+) Length 246 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag ATN06_RS12275 Protein ID WP_060630865.1
Coordinates 2349245..2349370 (+) Length 42 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ATN06_RS12250 2344088..2344870 + 783 WP_060630862.1 class I SAM-dependent methyltransferase -
ATN06_RS12255 2345028..2346713 - 1686 WP_060630863.1 alpha-keto acid decarboxylase family protein -
ATN06_RS12260 2346820..2347302 + 483 WP_060630864.1 MarR family winged helix-turn-helix transcriptional regulator -
ATN06_RS12265 2347469..2348206 + 738 WP_001980023.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
ATN06_RS12270 2348395..2349132 + 738 WP_060633134.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
ATN06_RS12275 2349245..2349370 + 126 WP_060630865.1 hypothetical protein Antitoxin
ATN06_RS29205 2349447..2349623 + 177 WP_000808045.1 hypothetical protein -
ATN06_RS12285 2349767..2351236 + 1470 WP_060630866.1 beta-Ala-His dipeptidase -
ATN06_RS12290 2351785..2352255 - 471 WP_060630867.1 DUF5065 family protein -
ATN06_RS12295 2352710..2353369 + 660 WP_060630868.1 CatB-related O-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(9-243)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 246 a.a.        Molecular weight: 28316.06 Da        Isoelectric Point: 9.3082

>T58205 WP_060633134.1 NZ_CP013274:2348395-2349132 [Bacillus thuringiensis]
VISNIRIGLFILAIVFLVLVFFYWKNEELYEEKKQRIRKTWYGVFIISVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEKEYTKSLNAFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSTIIPLEYIEQLNEQKAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK

Download         Length: 738 bp

>T58205 NZ_CP013274:2348395-2349132 [Bacillus thuringiensis]
GTGATCTCTAACATTCGAATCGGCTTATTTATTTTAGCAATCGTTTTTCTAGTACTTGTTTTCTTTTATTGGAAAAACGA
AGAGTTGTACGAGGAGAAGAAGCAACGTATTAGAAAGACTTGGTATGGGGTGTTTATAATATCAGTCACCGTGTATTTCA
TGATAAAAGGAATTGATTTAACCCTCTGGAAAAATCTTTTAATGTTCACTGCAATGGTTATTTTCGTTGATATTGCATTT
ATTTTAACACCGAATATTTCAGAAATATGGGGAGCGAAATTTAGCGATATCGGCAAGACGGTTCAATCGATAAAACGTTC
ATTAATTGCTTCTAAAGCAAGAGGAGAAATATACACAACAATCATTCAAAATGTCAATCCAGCAGTGTTCGGTACGATGG
AATGGCATACGGAGAAAGAATATACAAAAAGCTTAAACGCATTTTTAGATTCGTATGGGGAAAAGATTGGAGCAAAAATT
GTTGTATTTGAAGCGGCAAAGGAATTAAATACAAACTTTCGTGGTATCCGTTCTCAATTTAGTACTATCATTCCGTTAGA
GTACATTGAGCAATTGAATGAGCAGAAAGCAGTGCAAGTAGAAAATGTCGGAATTATACCAGCAAAAATAGTGAGTGATG
TTTTCATTGTTATTGATGGGAAGAAAAATAACCTGCAAGATCGGGATTTTGAAAATGTATATAATTTAACTATACATCAT
AGTTATTTTAGTAAATAA

Antitoxin


Download         Length: 42 a.a.        Molecular weight: 4860.23 Da        Isoelectric Point: 3.9507

>AT58205 WP_060630865.1 NZ_CP013274:2349245-2349370 [Bacillus thuringiensis]
VIKDNNNDFFKEDNEDTTDFSLIKGDTLQQVEDLEDELKRK

Download         Length: 126 bp

>AT58205 NZ_CP013274:2349245-2349370 [Bacillus thuringiensis]
GTGATAAAAGATAATAACAATGATTTTTTTAAAGAAGATAATGAAGATACAACGGATTTCTCGTTAATAAAAGGAGATAC
ATTACAGCAAGTAGAAGATTTAGAAGATGAATTAAAAAGAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References