58198

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 2087551..2088390 Replicon chromosome
Accession NZ_CP013264
Organism Sphingobium baderi strain DE-13

Toxin (Protein)


Gene name tacT Uniprot ID A0A0S3EYY3
Locus tag ATN00_RS10355 Protein ID WP_062064438.1
Coordinates 2087551..2088066 (-) Length 172 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A0S3EYZ1
Locus tag ATN00_RS10360 Protein ID WP_062064445.1
Coordinates 2088082..2088390 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ATN00_RS10325 2082946..2083524 + 579 WP_062064427.1 S26 family signal peptidase -
ATN00_RS10330 2083505..2083852 + 348 WP_062064429.1 DUF736 domain-containing protein -
ATN00_RS10335 2083888..2084232 + 345 WP_062064431.1 DUF736 domain-containing protein -
ATN00_RS10340 2084237..2084944 + 708 WP_062064433.1 lytic transglycosylase domain-containing protein -
ATN00_RS10345 2084941..2085522 + 582 WP_062064435.1 hypothetical protein -
ATN00_RS10350 2085761..2087536 + 1776 WP_062064436.1 VirD2 family relaxase/mobilization nuclease -
ATN00_RS10355 2087551..2088066 - 516 WP_062064438.1 GNAT family N-acetyltransferase Toxin
ATN00_RS10360 2088082..2088390 - 309 WP_062064445.1 DUF1778 domain-containing protein Antitoxin
ATN00_RS10365 2088473..2090458 + 1986 WP_062064447.1 conjugal transfer protein TraG -
ATN00_RS10370 2090467..2090889 + 423 WP_062064448.1 ribbon-helix-helix domain-containing protein -
ATN00_RS10375 2090985..2091260 + 276 WP_197413741.1 type II toxin-antitoxin system ParD family antitoxin -
ATN00_RS10380 2091330..2091695 - 366 WP_062064450.1 hypothetical protein -
ATN00_RS10385 2091948..2092934 + 987 WP_062064452.1 P-type conjugative transfer ATPase TrbB -
ATN00_RS10390 2092931..2093263 + 333 WP_062064454.1 TrbC/VirB2 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(48-150)

Antitoxin

Vibrio phage ICP1, Orf50

(14-101)


Sequences

Toxin        


Download         Length: 172 a.a.        Molecular weight: 18179.96 Da        Isoelectric Point: 8.5126

>T58198 WP_062064438.1 NZ_CP013264:c2088066-2087551 [Sphingobium baderi]
VADIRITPPARLTADHDVAGFANGVHASLDDWLRDRALASEGSSARTYVVCNAAEPRRVVGYYTITTAMEQRAALPSAKL
RRGMPDRVPLLLIGRLAVDAGFQGIGLGADLLADALRRCAAAAEIAGARAVIVHAIDEKAAAFYARHGFIPTSLGELVML
LPIEAIRSRPN

Download         Length: 516 bp

>T58198 NZ_CP013264:c2088066-2087551 [Sphingobium baderi]
GTGGCGGACATCCGCATCACGCCACCCGCGCGTCTGACCGCCGATCACGATGTCGCGGGCTTCGCCAATGGCGTGCATGC
CTCGCTCGATGACTGGCTGCGGGACCGCGCGCTGGCGAGCGAGGGGAGTTCGGCGCGCACCTATGTCGTCTGCAATGCCG
CCGAGCCGCGCCGGGTGGTCGGCTACTATACGATCACGACCGCGATGGAGCAGCGGGCTGCTCTGCCGTCCGCGAAGCTG
CGGCGCGGCATGCCCGACCGGGTGCCGCTGCTCCTGATCGGCCGGCTCGCCGTTGATGCCGGGTTCCAGGGCATCGGCCT
TGGCGCCGATCTTCTGGCCGATGCGCTCCGGCGCTGCGCCGCGGCAGCCGAGATTGCCGGTGCGCGCGCGGTGATCGTTC
ATGCGATCGACGAAAAGGCGGCGGCGTTTTATGCGCGGCACGGGTTTATCCCTACCTCGCTCGGCGAACTGGTCATGCTG
CTGCCGATCGAGGCAATCCGCTCGCGGCCGAACTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11431.07 Da        Isoelectric Point: 8.8725

>AT58198 WP_062064445.1 NZ_CP013264:c2088390-2088082 [Sphingobium baderi]
MAQTTPAHPNGRASARKDDVIQIRASAGMKAILTRAAALRGQKLSEFMLDSARREAEDAILDQRTFFLDAEQHEQFLAML
DAPPAPSDALQTLMRRKPIWER

Download         Length: 309 bp

>AT58198 NZ_CP013264:c2088390-2088082 [Sphingobium baderi]
ATGGCGCAGACGACACCTGCACATCCGAACGGGCGGGCTTCCGCCCGCAAGGACGATGTCATCCAGATCAGGGCGTCGGC
GGGTATGAAGGCCATTCTCACCCGTGCCGCCGCGCTGCGCGGTCAGAAGCTGTCCGAGTTCATGCTCGACAGCGCGCGGC
GCGAAGCGGAGGACGCCATTCTCGATCAGCGCACCTTCTTCCTCGACGCGGAGCAGCATGAGCAATTCCTCGCCATGCTC
GATGCCCCGCCCGCGCCGTCCGACGCTCTGCAGACCCTCATGCGGCGCAAGCCGATCTGGGAACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0S3EYY3

Antitoxin

Source ID Structure
AlphaFold DB A0A0S3EYZ1

References