Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
Location | 219517..220076 | Replicon | chromosome |
Accession | NZ_CP013264 | ||
Organism | Sphingobium baderi strain DE-13 |
Toxin (Protein)
Gene name | parE | Uniprot ID | A0A0J8A5F8 |
Locus tag | ATN00_RS01110 | Protein ID | WP_059153568.1 |
Coordinates | 219783..220076 (+) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A0S3EUK8 |
Locus tag | ATN00_RS01105 | Protein ID | WP_062061055.1 |
Coordinates | 219517..219795 (+) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ATN00_RS01085 | 216384..217004 | + | 621 | WP_008832583.1 | recombinase family protein | - |
ATN00_RS01090 | 217001..217531 | + | 531 | WP_062061046.1 | GNAT family N-acetyltransferase | - |
ATN00_RS01095 | 217589..218223 | + | 635 | Protein_214 | transposase | - |
ATN00_RS01100 | 218566..219126 | - | 561 | WP_062061052.1 | recombinase family protein | - |
ATN00_RS01105 | 219517..219795 | + | 279 | WP_062061055.1 | CopG family ribbon-helix-helix protein | Antitoxin |
ATN00_RS01110 | 219783..220076 | + | 294 | WP_059153568.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
ATN00_RS23270 | 220095..220190 | + | 96 | Protein_218 | histidine phosphatase family protein | - |
ATN00_RS22680 | 220205..220486 | - | 282 | WP_082635049.1 | WGR domain-containing protein | - |
ATN00_RS01125 | 220923..222296 | - | 1374 | WP_062061067.1 | DUF2384 domain-containing protein | - |
ATN00_RS01135 | 222777..223775 | - | 999 | WP_156415190.1 | tyrosine-type recombinase/integrase | - |
ATN00_RS01140 | 223736..224107 | - | 372 | WP_030092871.1 | hypothetical protein | - |
ATN00_RS01145 | 224141..224506 | - | 366 | WP_030092870.1 | hypothetical protein | - |
ATN00_RS01150 | 224503..224835 | - | 333 | WP_030092869.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | tufA | 112541..293149 | 180608 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 10942.43 Da Isoelectric Point: 7.4007
>T58195 WP_059153568.1 NZ_CP013264:219783-220076 [Sphingobium baderi]
VPRLIWTAEALADVDRLHRWLKTKDADAARRAVAAIRGGVRILAATPHIGRPTEDMESEYREKLIDFGNSGYVVLYHFDG
ETVALLAVRHQREAGYQ
VPRLIWTAEALADVDRLHRWLKTKDADAARRAVAAIRGGVRILAATPHIGRPTEDMESEYREKLIDFGNSGYVVLYHFDG
ETVALLAVRHQREAGYQ
Download Length: 294 bp
>T58195 NZ_CP013264:219783-220076 [Sphingobium baderi]
GTGCCACGTCTGATCTGGACGGCCGAAGCACTGGCCGATGTTGACCGGCTCCATCGCTGGTTGAAGACCAAAGACGCCGA
CGCAGCGAGACGCGCGGTCGCCGCGATCCGGGGAGGGGTTCGGATTCTGGCGGCAACCCCGCACATCGGCCGACCAACTG
AAGATATGGAGTCCGAGTATCGGGAAAAGCTGATCGACTTTGGAAACAGCGGCTATGTTGTCCTGTATCACTTCGATGGT
GAGACGGTGGCGCTGTTGGCCGTGCGCCACCAAAGGGAGGCGGGTTATCAATAG
GTGCCACGTCTGATCTGGACGGCCGAAGCACTGGCCGATGTTGACCGGCTCCATCGCTGGTTGAAGACCAAAGACGCCGA
CGCAGCGAGACGCGCGGTCGCCGCGATCCGGGGAGGGGTTCGGATTCTGGCGGCAACCCCGCACATCGGCCGACCAACTG
AAGATATGGAGTCCGAGTATCGGGAAAAGCTGATCGACTTTGGAAACAGCGGCTATGTTGTCCTGTATCACTTCGATGGT
GAGACGGTGGCGCTGTTGGCCGTGCGCCACCAAAGGGAGGCGGGTTATCAATAG
Antitoxin
Download Length: 93 a.a. Molecular weight: 10686.02 Da Isoelectric Point: 6.0877
>AT58195 WP_062061055.1 NZ_CP013264:219517-219795 [Sphingobium baderi]
MATATSIKLDDALKERVQHLANARRRSSHWIMREAIAQYVEREEKREAFKQDAIRAWENYQQTGLHVTLEEADVWLAKLE
AGEDAEPPKCHV
MATATSIKLDDALKERVQHLANARRRSSHWIMREAIAQYVEREEKREAFKQDAIRAWENYQQTGLHVTLEEADVWLAKLE
AGEDAEPPKCHV
Download Length: 279 bp
>AT58195 NZ_CP013264:219517-219795 [Sphingobium baderi]
ATGGCAACGGCAACATCTATTAAGCTGGACGATGCCCTGAAAGAGCGTGTGCAGCACCTGGCCAACGCGCGCCGGCGCAG
CTCGCATTGGATTATGCGCGAAGCTATCGCGCAGTATGTCGAGCGCGAGGAAAAGCGCGAGGCATTCAAACAGGACGCCA
TTCGGGCATGGGAAAACTATCAGCAGACGGGCTTGCATGTGACGCTTGAGGAAGCCGATGTCTGGTTGGCGAAGCTCGAA
GCGGGTGAGGATGCGGAGCCGCCTAAGTGCCACGTCTGA
ATGGCAACGGCAACATCTATTAAGCTGGACGATGCCCTGAAAGAGCGTGTGCAGCACCTGGCCAACGCGCGCCGGCGCAG
CTCGCATTGGATTATGCGCGAAGCTATCGCGCAGTATGTCGAGCGCGAGGAAAAGCGCGAGGCATTCAAACAGGACGCCA
TTCGGGCATGGGAAAACTATCAGCAGACGGGCTTGCATGTGACGCTTGAGGAAGCCGATGTCTGGTTGGCGAAGCTCGAA
GCGGGTGAGGATGCGGAGCCGCCTAAGTGCCACGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0J8A5F8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0S3EUK8 |