Detailed information of TA system TA058181

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 5154049..5154568
• Replicon: chromosome
• Accession: NZ_CP013236
• Organism: Collimonas pratensis strain Ter291

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A127R555
• Locus tag: CPter291_RS23085
• Protein ID: WP_062119467.1
• Coordinates: 5154049..5154330 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CPter291_RS23090
• Protein ID: WP_061944852.1
• Coordinates: 5154320..5154568 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CPter291_RS23070	5150003..5151781	+	1779	WP_062119458.1	FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	-
CPter291_RS23075	5151799..5152116	-	318	WP_062119461.1	YXWGXW repeat-containing protein	-
CPter291_RS23080	5152385..5154016	+	1632	WP_062119464.1	NAD(P)/FAD-dependent oxidoreductase	-
CPter291_RS23085	5154049..5154330	-	282	WP_062119467.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CPter291_RS23090	5154320..5154568	-	249	WP_061944852.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CPter291_RS23095	5154790..5155998	-	1209	WP_197481615.1	c-type cytochrome	-
CPter291_RS23100	5156025..5157458	-	1434	WP_062119473.1	metallophosphoesterase	-
CPter291_RS23105	5157610..5157972	-	363	WP_061946562.1	hypothetical protein	-
CPter291_RS23110	5158116..5158685	+	570	WP_062119476.1	hypothetical protein	-
CPter291_RS23115	5158875..5159282	+	408	WP_061944864.1	biopolymer transporter ExbD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11027.88 Da
• Isoelectric Point: 10.8571

>T58181 WP_062119467.1 NZ_CP013236:c5154330-5154049 [Collimonas pratensis]
MNFELAFLEEALKEWRKLDQGIREQFKKKLEERLLSPHVPSAQLSGSRSRYKIKLRQAGYRLVYEVRDKQLIVLVVPVGK
RERNAAYKAAERR

Nucleotide

• Length: 282 bp

>T58181 NZ_CP013236:c5154330-5154049 [Collimonas pratensis]
ATGAACTTTGAGCTCGCGTTTCTTGAAGAAGCGTTGAAGGAATGGCGCAAGCTTGATCAGGGCATACGCGAGCAATTCAA
GAAAAAACTGGAAGAACGATTGTTGAGTCCGCATGTGCCATCGGCACAGCTTTCCGGCTCTCGCAGCCGCTATAAAATCA
AGCTGCGCCAAGCCGGTTACCGTCTCGTCTACGAGGTGCGCGACAAGCAACTGATCGTATTGGTGGTGCCCGTGGGCAAG
CGAGAGCGCAATGCCGCATACAAGGCTGCCGAAAGACGTTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 8834.25 Da
• Isoelectric Point: 4.7023

>AT58181 WP_061944852.1 NZ_CP013236:c5154568-5154320 [Collimonas pratensis]
MAHLILAETTASVSELKKDPMGTVAAGEGFPVAILNRNQPAFYCVPAKAYEALMNKLEDMELNAIADARSSQAVIKVKLD
EL

Nucleotide

• Length: 249 bp

>AT58181 NZ_CP013236:c5154568-5154320 [Collimonas pratensis]
ATGGCACACCTTATTCTTGCCGAAACAACCGCCAGCGTTTCCGAGCTAAAGAAAGACCCTATGGGAACTGTCGCTGCCGG
CGAAGGATTTCCCGTGGCTATCTTGAACCGGAACCAGCCTGCCTTCTATTGCGTTCCGGCGAAGGCTTATGAGGCGCTGA
TGAACAAACTGGAAGACATGGAGCTGAATGCCATTGCGGATGCGCGCAGCAGCCAGGCGGTCATCAAGGTCAAGCTGGAT
GAACTTTGA

Structures

Toxin

• AlphaFold DB: A0A127R555