Detailed information of TA system TA058179

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PumA-relB/upstrm_HI1419-dnstrm_HI1420
• Location: 3595712..3596305
• Replicon: chromosome
• Accession: NZ_CP013236
• Organism: Collimonas pratensis strain Ter291

Toxin (Protein)

• Gene name: PumA
• Uniprot ID: -
• Locus tag: CPter291_RS16200
• Protein ID: WP_062116980.1
• Coordinates: 3596015..3596305 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A127Q3F4
• Locus tag: CPter291_RS16195
• Protein ID: WP_061939531.1
• Coordinates: 3595712..3596005 (-)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CPter291_RS16175	3591945..3592304	-	360	WP_061939538.1	50S ribosomal protein L20	-
CPter291_RS16180	3592325..3592522	-	198	WP_061539612.1	50S ribosomal protein L35	-
CPter291_RS16185	3592789..3593313	-	525	WP_081992442.1	translation initiation factor IF-3	-
CPter291_RS16190	3593373..3595280	-	1908	WP_062116976.1	threonine--tRNA ligase	-
CPter291_RS26075	3595499..3595711	-	213	WP_156480105.1	hypothetical protein	-
CPter291_RS16195	3595712..3596005	-	294	WP_061939531.1	putative addiction module antidote protein	Antitoxin
CPter291_RS16200	3596015..3596305	-	291	WP_062116980.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CPter291_RS16205	3596609..3598096	-	1488	WP_062116983.1	efflux transporter outer membrane subunit	-
CPter291_RS16210	3598127..3601222	-	3096	WP_062116987.1	efflux RND transporter permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Addiction module killer protein, predicted (2-96)

Antitoxin

• Cro/C1-type helix-turn-helix domain (48-92)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10790.39 Da
• Isoelectric Point: 7.6753

>T58179 WP_062116980.1 NZ_CP013236:c3596305-3596015 [Collimonas pratensis]
VKTIQTTSVFEHWFASLRDRCVKARIQVRIDRAELGNFGDCKAVGEGVSEMRIHFGCGCRVYFMQRGDEIVILLAGGDKS
TQDKDINTALELARQL

Nucleotide

• Length: 291 bp

>T58179 NZ_CP013236:c3596305-3596015 [Collimonas pratensis]
GTGAAAACTATTCAAACAACGTCTGTATTTGAGCATTGGTTTGCCTCGTTGCGCGATCGTTGCGTCAAAGCGCGGATCCA
AGTGCGCATTGACCGTGCTGAGCTGGGTAATTTTGGCGATTGCAAAGCTGTCGGTGAAGGTGTTTCCGAGATGCGGATTC
ACTTCGGCTGTGGCTGCCGGGTCTACTTTATGCAACGTGGCGATGAGATAGTGATATTGCTTGCGGGTGGTGACAAGTCG
ACGCAGGACAAGGACATCAATACCGCGTTGGAATTGGCGCGTCAACTTTAG

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10261.66 Da
• Isoelectric Point: 6.0625

>AT58179 WP_061939531.1 NZ_CP013236:c3596005-3595712 [Collimonas pratensis]
MGTIKLRQWDSAEHLQTAADIAAYVDACLEEAGDDPAFIAHALGNVARAHGMSQVARDTGLARESLYKALSGEGNPEFGT
ILKVMKALGLRLHASVA

Nucleotide

• Length: 294 bp

>AT58179 NZ_CP013236:c3596005-3595712 [Collimonas pratensis]
ATGGGAACGATCAAACTGCGTCAGTGGGATTCCGCAGAGCATCTGCAAACCGCGGCCGATATTGCTGCCTATGTCGATGC
CTGCCTTGAAGAAGCGGGTGACGATCCTGCTTTCATCGCACATGCTTTGGGCAACGTTGCGCGCGCGCATGGCATGAGCC
AGGTGGCGCGCGATACCGGGCTGGCGCGCGAAAGCCTGTATAAGGCGCTATCGGGCGAGGGTAATCCCGAGTTCGGAACC
ATTCTGAAAGTCATGAAAGCACTTGGCTTAAGACTGCACGCGAGCGTGGCATAA

Structures

Antitoxin

• AlphaFold DB: A0A127Q3F4