Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2176152..2176820 Replicon chromosome
Accession NZ_CP013236
Organism Collimonas pratensis strain Ter291

Toxin (Protein)


Gene name vapC Uniprot ID A0A127Q6I1
Locus tag CPter291_RS09935 Protein ID WP_061941694.1
Coordinates 2176410..2176820 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A127QX09
Locus tag CPter291_RS09930 Protein ID WP_061941696.1
Coordinates 2176152..2176364 (+) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPter291_RS09905 2171333..2172082 + 750 WP_062114433.1 SDR family oxidoreductase -
CPter291_RS09910 2172327..2172782 + 456 WP_061946288.1 glycine zipper 2TM domain-containing protein -
CPter291_RS09915 2172887..2173468 - 582 WP_099047209.1 XRE family transcriptional regulator -
CPter291_RS09920 2173626..2174861 + 1236 WP_062114435.1 glycine C-acetyltransferase -
CPter291_RS09925 2174884..2175849 + 966 WP_062114437.1 NAD-dependent epimerase/dehydratase family protein -
CPter291_RS09930 2176152..2176364 + 213 WP_061941696.1 hypothetical protein Antitoxin
CPter291_RS09935 2176410..2176820 + 411 WP_061941694.1 type II toxin-antitoxin system VapC family toxin Toxin
CPter291_RS09940 2176857..2177873 - 1017 WP_062114439.1 hypothetical protein -
CPter291_RS09945 2177870..2178469 - 600 WP_062114441.1 sigma-70 family RNA polymerase sigma factor -
CPter291_RS09950 2178675..2181623 + 2949 WP_062114443.1 DUF2135 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Uncharacterised conserved protein UCP008505

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15174.21 Da        Isoelectric Point: 4.8780

>T58178 WP_061941694.1 NZ_CP013236:2176410-2176820 [Collimonas pratensis]
VYLLDTNVISESRKGAKANRGTQEFWRSVDLDAIYLPVQSIGEIRRGVEIVKRRGDSAQAKMLETWLQTLTTEYADRILS
FDDDCAQVWGCLMSADNQHPIDKQIAAIALIHSMTVVTRNTGDFIGTGVDLINPFS

Download         Length: 411 bp

>T58178 NZ_CP013236:2176410-2176820 [Collimonas pratensis]
GTGTATCTGCTAGATACCAATGTCATCAGCGAGTCCCGTAAAGGGGCAAAAGCCAACCGCGGAACGCAGGAGTTCTGGCG
CTCGGTTGACCTCGATGCGATTTATCTGCCGGTGCAAAGCATAGGCGAAATACGCCGCGGCGTTGAAATCGTCAAGCGCC
GTGGCGATTCGGCGCAGGCCAAAATGCTGGAGACATGGCTGCAGACGCTGACCACGGAATATGCTGATCGTATCCTGTCG
TTTGACGACGACTGTGCCCAGGTGTGGGGGTGTCTGATGTCTGCCGACAATCAACATCCGATCGATAAGCAAATTGCCGC
GATCGCCTTGATCCATAGCATGACTGTCGTTACGCGTAATACCGGCGATTTTATCGGTACAGGCGTGGACCTGATAAATC
CATTTTCCTGA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 7884.93 Da        Isoelectric Point: 7.2049

>AT58178 WP_061941696.1 NZ_CP013236:2176152-2176364 [Collimonas pratensis]
MATNLVVRNVEEELTLALKQQAAAHGRSAEAEHREILRAALQRPKRRSLVDFLLSMPNVGEDKDFDARNS

Download         Length: 213 bp

>AT58178 NZ_CP013236:2176152-2176364 [Collimonas pratensis]
ATGGCTACAAACCTGGTGGTGAGAAACGTGGAAGAAGAACTTACTCTGGCACTCAAGCAACAGGCGGCGGCGCATGGCCG
CAGCGCAGAAGCCGAGCACAGGGAAATCCTGCGGGCGGCGCTGCAGCGTCCGAAGCGGCGCTCGCTGGTGGACTTCTTGT
TGAGCATGCCGAATGTCGGGGAAGACAAGGACTTCGATGCGCGCAATAGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A127Q6I1

Antitoxin

Source ID Structure
AlphaFold DB A0A127QX09

References