Detailed information of TA system TA058177

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/Tad-HTH_37
• Location: 2103178..2103878
• Replicon: chromosome
• Accession: NZ_CP013236
• Organism: Collimonas pratensis strain Ter291

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: CPter291_RS25310
• Protein ID: WP_082807024.1
• Coordinates: 2103178..2103540 (+)
• Length: 121 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: CPter291_RS09610
• Protein ID: WP_082807025.1
• Coordinates: 2103537..2103878 (+)
• Length: 114 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CPter291_RS09595	2100821..2102311	-	1491	WP_062114316.1	DNA polymerase Y family protein	-
CPter291_RS09600	2102244..2103023	-	780	WP_062114321.1	translesion DNA synthesis-associated protein ImuA	-
CPter291_RS25310	2103178..2103540	+	363	WP_082807024.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CPter291_RS09610	2103537..2103878	+	342	WP_082807025.1	helix-turn-helix domain-containing protein	Antitoxin
CPter291_RS09615	2103860..2104573	-	714	WP_062120640.1	amino acid ABC transporter permease	-
CPter291_RS09620	2104576..2105313	-	738	WP_197481714.1	amino acid ABC transporter permease	-
CPter291_RS09625	2105448..2106263	-	816	WP_062114331.1	ABC transporter substrate-binding protein	-
CPter291_RS09630	2106473..2107231	+	759	WP_062120644.1	SDR family oxidoreductase	-
CPter291_RS09635	2107265..2107834	-	570	WP_061941799.1	flavin reductase family protein	-
CPter291_RS09640	2108636..2108833	+	198	WP_062114336.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (17-110)

Antitoxin

• Cro/C1-type helix-turn-helix domain (38-94)

Sequences

Toxin

Protein

• Length: 121 a.a.
• Molecular weight: 13341.52 Da
• Isoelectric Point: 9.1387

>T58177 WP_082807024.1 NZ_CP013236:2103178-2103540 [Collimonas pratensis]
MISSFLRPLRWVGSAKKDLGEMPVEVQAAFGYALHLAQIGSKHDQAKPLKGFGGAGVLEIVEDCQGDTYRAIYTVRCVEE
LYVLHCFQKKSVSGSATPKPDMDLIRTRLKTVIAMQRSRE

Nucleotide

• Length: 363 bp

>T58177 NZ_CP013236:2103178-2103540 [Collimonas pratensis]
ATGATATCTTCTTTTTTACGGCCTTTGCGCTGGGTTGGATCAGCGAAAAAAGATTTGGGTGAGATGCCGGTAGAAGTTCA
GGCTGCTTTTGGTTATGCGCTGCATTTGGCCCAAATCGGCAGTAAGCACGATCAGGCCAAGCCGTTGAAAGGCTTTGGCG
GCGCAGGTGTCCTGGAAATAGTAGAAGACTGCCAGGGGGATACATATCGCGCCATATACACAGTACGCTGTGTCGAGGAG
CTTTACGTACTGCATTGTTTTCAGAAAAAGTCCGTTAGCGGTAGCGCCACACCCAAGCCGGATATGGATTTGATTCGAAC
GCGATTGAAAACTGTAATTGCAATGCAAAGGAGCAGAGAGTGA

Antitoxin

Protein

• Length: 114 a.a.
• Molecular weight: 12447.49 Da
• Isoelectric Point: 9.7512

>AT58177 WP_082807025.1 NZ_CP013236:2103537-2103878 [Collimonas pratensis]
VNQKVTFNGIDIEIGSDNPYADLGFPDAEEMLVKAKLAHEIAQIIKGRHLTQQRAAELLGMPQPKLSEMLRGKFRGISQA
KMVECLNRLGRDVDIVVKKTGRNAIGHTQVVVA

Nucleotide

• Length: 342 bp

>AT58177 NZ_CP013236:2103537-2103878 [Collimonas pratensis]
GTGAATCAGAAAGTTACTTTTAATGGCATCGATATTGAAATCGGCAGCGACAATCCCTATGCCGACCTGGGCTTCCCTGA
TGCCGAAGAGATGCTCGTCAAGGCCAAGCTGGCTCATGAAATCGCACAAATCATCAAGGGCCGGCACTTGACTCAGCAGA
GAGCCGCCGAACTGTTGGGAATGCCCCAACCCAAGCTCTCGGAAATGCTGCGAGGAAAATTCAGAGGCATCAGCCAGGCC
AAGATGGTGGAGTGCTTGAACCGTCTAGGCCGTGACGTCGACATCGTGGTGAAGAAAACCGGCCGGAACGCAATCGGCCA
CACTCAGGTAGTGGTGGCCTGA