Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1725421..1727160 Replicon chromosome
Accession NZ_CP013235
Organism Collimonas arenae strain Ter282

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag CAter282_RS08045 Protein ID WP_061533038.1
Coordinates 1725421..1726314 (+) Length 298 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID A0A127QHJ5
Locus tag CAter282_RS08050 Protein ID WP_061533039.1
Coordinates 1726324..1727160 (+) Length 279 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAter282_RS21830 1720696..1720872 - 177 WP_156477085.1 hypothetical protein -
CAter282_RS08025 1721011..1721691 - 681 WP_061535234.1 hypothetical protein -
CAter282_RS21835 1722283..1722438 + 156 WP_156477086.1 hypothetical protein -
CAter282_RS08030 1722435..1723742 + 1308 WP_061537097.1 MFS transporter -
CAter282_RS08035 1724081..1724845 + 765 WP_061533036.1 SDR family oxidoreductase -
CAter282_RS08040 1724880..1725419 + 540 WP_061533037.1 cupin domain-containing protein -
CAter282_RS08045 1725421..1726314 + 894 WP_061533038.1 alpha/beta hydrolase Toxin
CAter282_RS08050 1726324..1727160 + 837 WP_061533039.1 IclR family transcriptional regulator Antitoxin
CAter282_RS08055 1727166..1727975 + 810 WP_061533040.1 SDR family oxidoreductase -
CAter282_RS08060 1727968..1729677 + 1710 WP_061533041.1 thiamine pyrophosphate-binding protein -
CAter282_RS08065 1729688..1730494 + 807 WP_061533042.1 aspartate dehydrogenase -
CAter282_RS08070 1730507..1731981 + 1475 Protein_1605 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(52-287)

Antitoxin

Transcription regulator IclR, N-terminal

(20-69)


Sequences

Toxin        


Download         Length: 298 a.a.        Molecular weight: 31711.84 Da        Isoelectric Point: 4.6840

>T58171 WP_061533038.1 NZ_CP013235:1725421-1726314 [Collimonas arenae]
MNMTAPVAAVTTELQEALELLDRRFEERSADVDGATVSYRSCGNAADSGRCVVLLHGIGSGAASWLQCALALQQDAQVIA
WNAPGYGGSTPLPMTHPAAADYALRLQQLLQALDVSDCLLVGHSLGAMMATSYVAAGYGHVKQLLLFSPAQGYGSDDKRQ
RGLEMTRQRLDALATLGVTGMAQKSPERMLSAQADTADRAWVSWNTQQLNLAGYAQAVQMLCGGDIHRDLPAAISSEVSV
AVYCGDVDIVTTPQDSRALADSFQLPFQLIDDAGHACYVEQPEAVAAVIRRHLYQLS

Download         Length: 894 bp

>T58171 NZ_CP013235:1725421-1726314 [Collimonas arenae]
ATGAACATGACAGCGCCCGTGGCTGCCGTTACTACAGAACTGCAGGAAGCGCTCGAATTGCTCGACCGGCGCTTCGAGGA
GCGCAGTGCCGACGTCGACGGCGCGACGGTGTCCTATCGCAGTTGCGGCAACGCTGCCGATAGCGGTCGCTGCGTGGTGC
TGTTACACGGCATTGGTTCGGGCGCGGCATCGTGGCTGCAGTGCGCATTGGCGTTGCAACAGGACGCGCAAGTGATTGCC
TGGAATGCACCGGGCTACGGTGGTTCGACACCGTTGCCGATGACGCATCCGGCTGCGGCGGACTACGCATTGCGCCTGCA
GCAGTTGTTGCAGGCGCTGGATGTCAGTGATTGTCTGCTGGTCGGACATTCGCTTGGCGCCATGATGGCGACGTCTTACG
TGGCTGCTGGTTACGGGCATGTCAAGCAGCTGTTGCTGTTTAGTCCGGCGCAGGGCTACGGCAGCGACGACAAGCGCCAG
CGCGGACTTGAGATGACGCGGCAACGCCTGGACGCGTTGGCGACATTGGGCGTGACAGGCATGGCGCAGAAGAGCCCCGA
GCGGATGCTGTCGGCGCAAGCCGACACGGCGGACCGCGCCTGGGTAAGCTGGAATACGCAACAGTTGAATCTGGCCGGTT
ATGCGCAAGCGGTGCAGATGCTGTGTGGTGGCGATATCCATCGGGATCTGCCGGCAGCGATATCGTCAGAGGTATCGGTT
GCGGTATATTGCGGCGACGTCGATATCGTCACGACGCCGCAGGACAGCAGGGCGTTGGCTGACAGTTTTCAGCTTCCGTT
CCAGCTGATCGATGATGCAGGCCATGCCTGTTATGTCGAGCAACCGGAAGCAGTCGCGGCAGTGATACGTCGTCACCTTT
ATCAACTTTCTTGA

Antitoxin


Download         Length: 279 a.a.        Molecular weight: 31130.61 Da        Isoelectric Point: 5.4610

>AT58171 WP_061533039.1 NZ_CP013235:1726324-1727160 [Collimonas arenae]
MNKPELPEEETQEKYLVPGLERGLRLLCEFSRQDKSLSAPELARRLSVPRSTVFRLLTTLERMGFVERNEGGRDYRLGMA
VLRLGFEYLASLELTEIGRPLLDRLRDQISYPCNLVVRDGRSIVYVAKSVTPTAFVSSVNVGTRLPAHATVLGRVLLEDL
SLAELRELYPEEHLESFSSNTPKTVVELFDMVQHDRERGYVLQEGFFETGISTIAAPVRDHSGKVVAAMGATIPLPHIDP
DQLGDIVRCVRDTAGELSGLLDHAPEKSSSKVVNMWRE

Download         Length: 837 bp

>AT58171 NZ_CP013235:1726324-1727160 [Collimonas arenae]
ATGAATAAACCAGAGTTGCCAGAAGAAGAGACGCAAGAAAAATACCTCGTGCCGGGACTGGAGCGCGGGTTGCGCCTGCT
ATGCGAATTCAGCCGGCAGGACAAGAGTCTGTCGGCGCCGGAGCTGGCGCGTCGCCTGAGCGTGCCGCGCTCGACGGTGT
TCCGCCTATTGACTACGCTGGAACGAATGGGGTTTGTGGAGCGCAACGAAGGTGGGCGCGATTATCGCCTTGGCATGGCA
GTGCTGCGCCTGGGTTTCGAATACCTGGCATCACTGGAGCTGACAGAAATCGGGCGGCCGTTGCTGGATCGCCTGCGCGA
CCAGATTTCCTATCCTTGCAACCTGGTGGTGCGCGATGGTCGTTCGATCGTGTATGTCGCCAAGTCGGTGACGCCGACCG
CATTTGTCAGTTCGGTCAATGTCGGTACCCGGTTGCCAGCACACGCCACTGTGCTCGGCCGCGTGCTGCTGGAGGATTTG
TCGCTGGCGGAGTTGCGCGAACTGTATCCGGAAGAACATCTGGAGAGCTTCTCCAGTAACACGCCGAAGACTGTGGTCGA
GCTGTTCGACATGGTGCAGCACGATCGCGAACGCGGTTATGTGTTACAGGAAGGCTTTTTTGAGACCGGCATTTCGACCA
TTGCGGCGCCAGTCCGTGACCATTCCGGCAAGGTAGTGGCGGCGATGGGAGCGACCATTCCTTTACCGCACATCGATCCT
GACCAGTTGGGCGACATCGTGCGCTGCGTGCGTGATACCGCAGGTGAATTGTCCGGTTTGCTTGACCATGCTCCCGAGAA
GTCGAGCAGCAAGGTCGTCAACATGTGGCGGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A127QHJ5

References