58170

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 5701135..5702852 Replicon chromosome
Accession NZ_CP013234
Organism Collimonas pratensis strain Ter91

Toxin (Protein)


Gene name pmenT Uniprot ID A0A127QCL7
Locus tag CPter91_RS25330 Protein ID WP_061945606.1
Coordinates 5701135..5701776 (+) Length 214 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID A0A127QCK2
Locus tag CPter91_RS25335 Protein ID WP_061945608.1
Coordinates 5701776..5702852 (+) Length 359 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPter91_RS25310 5696888..5697502 + 615 WP_082793267.1 sorbitol dehydrogenase family protein -
CPter91_RS25315 5697505..5699106 + 1602 WP_061945602.1 GMC family oxidoreductase -
CPter91_RS25320 5699043..5700512 + 1470 WP_150119821.1 cytochrome c -
CPter91_RS25325 5700547..5701032 + 486 WP_061945604.1 asparaginase -
CPter91_RS25330 5701135..5701776 + 642 WP_061945606.1 DUF4433 domain-containing protein Toxin
CPter91_RS25335 5701776..5702852 + 1077 WP_061945608.1 macro domain-containing protein Antitoxin
CPter91_RS25340 5702933..5705119 - 2187 WP_205631639.1 M3 family metallopeptidase -
CPter91_RS25345 5705276..5706352 - 1077 WP_061945610.1 porin -
CPter91_RS25350 5706586..5707674 - 1089 WP_061945612.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 214 a.a.        Molecular weight: 24686.31 Da        Isoelectric Point: 7.9127

>T58170 WP_061945606.1 NZ_CP013234:5701135-5701776 [Collimonas pratensis]
MIYSNLNPDKALIWRITHRDNLPWILDNGLHCPKSNLLAPNYINIGNPDLIDKRRHRSVPIAPGGTLADYVPFYFTPFSV
MMKNIHSGWGVQQRPNDEIVIIVSSLYHVQSLDLPIVFTNAHAYPDWTNYYSDLAQLSEIDWPLLQRRDFKRDADDPRKM
ERYQAEALIYQRLPIQGVLGIVCYTEILKQSIGQQVQARGLTLPVYARTGWYF

Download         Length: 642 bp

>T58170 NZ_CP013234:5701135-5701776 [Collimonas pratensis]
ATGATTTATTCCAATCTCAATCCAGACAAGGCGCTGATCTGGCGTATTACCCACCGTGACAACTTACCGTGGATTTTGGA
CAATGGCTTGCATTGTCCAAAATCAAATTTACTGGCACCGAATTACATTAATATCGGTAATCCCGATTTAATCGATAAAC
GACGTCACCGCTCGGTGCCGATAGCGCCTGGCGGAACATTGGCAGATTATGTGCCCTTTTACTTCACACCGTTCTCTGTG
ATGATGAAGAACATCCATTCCGGCTGGGGCGTACAACAACGTCCTAACGACGAAATCGTGATTATTGTATCGAGTCTGTA
TCACGTGCAGTCGCTGGACTTGCCCATAGTGTTTACCAATGCCCATGCTTACCCGGACTGGACTAATTACTATAGCGATT
TGGCTCAACTTTCCGAGATCGACTGGCCCCTTTTGCAGAGGCGAGATTTCAAACGCGATGCGGATGATCCTCGTAAGATG
GAGCGCTATCAAGCTGAGGCGTTAATATACCAGCGCTTGCCAATTCAGGGCGTGCTCGGTATCGTTTGTTATACTGAGAT
ATTAAAACAAAGCATTGGGCAACAAGTACAGGCACGAGGCCTTACACTGCCGGTTTATGCGAGAACTGGGTGGTACTTCT
AA

Antitoxin


Download         Length: 359 a.a.        Molecular weight: 40575.73 Da        Isoelectric Point: 5.5114

>AT58170 WP_061945608.1 NZ_CP013234:5701776-5702852 [Collimonas pratensis]
MITFTQGNLLEAKVEALVNTVNTVGVMGKGIALMFKERFADNFQRYAAACKAKQVHTGRMFVTEVCELDGPRWIVNFPTK
QHWRAPSQMSWIVDGLQDLRRFVLDNKVKSIAIPPLGAGNGGLEWPLVREQIELALTDLQDVEITVFEPTNQYQNVAKRT
GVEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERSIKCYAPDNPLDLQFVAHKYGPYANRLDHLLNNLDGSYLH
CDKRISDADPLDVIWFDDERKVFLDTYLKSEAKPYVLALERTAALIDGFESPFGMELLATVDWLLTKENVSATIADVREG
LQNWPAGAADRKSRLFDERAIGIALERLSMRDNQVAMA

Download         Length: 1077 bp

>AT58170 NZ_CP013234:5701776-5702852 [Collimonas pratensis]
ATGATCACATTCACACAAGGCAATTTGCTAGAAGCCAAGGTAGAAGCGCTGGTCAATACCGTCAACACTGTGGGGGTAAT
GGGTAAAGGCATTGCGCTGATGTTCAAGGAACGCTTCGCAGATAATTTCCAACGTTATGCAGCCGCGTGTAAAGCCAAAC
AAGTTCACACCGGCCGGATGTTTGTGACGGAAGTGTGTGAGCTCGACGGTCCGCGCTGGATTGTCAACTTTCCCACCAAG
CAGCATTGGCGTGCACCGTCGCAAATGAGTTGGATAGTGGACGGATTGCAGGATTTGCGCCGTTTTGTGCTTGATAATAA
GGTCAAGTCGATTGCCATCCCGCCGCTCGGTGCGGGTAACGGTGGATTGGAGTGGCCTCTGGTTCGCGAACAGATCGAGT
TGGCATTGACGGATTTGCAGGACGTTGAGATCACGGTGTTCGAACCAACCAATCAATACCAAAATGTCGCTAAACGCACC
GGGGTGGAAAAGCTCACCCCCGCGCGGGCATTGATTGCCGAACTGGTGCGGCGTTATTGGGTGCTTGGCATGGAATGCAG
CCTGCTGGAAATCCAAAAATTGGCGTGGTTCTTAGAGCGCTCTATCAAATGCTATGCACCTGATAACCCATTAGATTTGC
AATTCGTCGCGCACAAATATGGCCCTTATGCTAACCGGTTGGATCATCTGCTGAATAATTTGGATGGCAGTTACCTGCAT
TGCGACAAGCGTATCAGTGACGCAGATCCACTTGACGTTATCTGGTTTGATGATGAGCGCAAAGTATTTCTGGACACGTA
TCTGAAAAGCGAAGCCAAACCGTATGTGCTGGCGCTGGAGCGCACTGCGGCCTTGATTGATGGCTTTGAATCTCCGTTTG
GCATGGAACTGCTGGCTACCGTCGACTGGCTGTTGACCAAAGAGAACGTCTCCGCAACGATTGCAGACGTGCGTGAAGGC
TTACAAAATTGGCCAGCAGGAGCGGCGGATCGCAAGAGTCGCCTGTTCGATGAACGGGCGATTGGCATTGCGTTGGAGCG
TCTTAGTATGCGGGACAATCAAGTAGCTATGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A127QCL7

Antitoxin

Source ID Structure
AlphaFold DB A0A127QCK2

References