Detailed information of TA system TA058169

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 5231449..5231968
• Replicon: chromosome
• Accession: NZ_CP013234
• Organism: Collimonas pratensis strain Ter91

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A127QBH8
• Locus tag: CPter91_RS23285
• Protein ID: WP_061944849.1
• Coordinates: 5231449..5231730 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CPter91_RS23290
• Protein ID: WP_061944852.1
• Coordinates: 5231720..5231968 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CPter91_RS23270	5227403..5229181	+	1779	WP_061944841.1	FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	-
CPter91_RS23275	5229199..5229516	-	318	WP_061944844.1	YXWGXW repeat-containing protein	-
CPter91_RS23280	5229785..5231416	+	1632	WP_061944847.1	NAD(P)/FAD-dependent oxidoreductase	-
CPter91_RS23285	5231449..5231730	-	282	WP_061944849.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CPter91_RS23290	5231720..5231968	-	249	WP_061944852.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CPter91_RS23295	5232190..5233425	-	1236	WP_061944855.1	c-type cytochrome	-
CPter91_RS23300	5233425..5234858	-	1434	WP_061944858.1	metallophosphoesterase	-
CPter91_RS23305	5235011..5235373	-	363	WP_061946562.1	hypothetical protein	-
CPter91_RS23310	5235526..5236095	+	570	WP_061944861.1	hypothetical protein	-
CPter91_RS23315	5236283..5236690	+	408	WP_061944864.1	biopolymer transporter ExbD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11001.84 Da
• Isoelectric Point: 10.8571

>T58169 WP_061944849.1 NZ_CP013234:c5231730-5231449 [Collimonas pratensis]
MNFELAFLEEALKEWRKLDQGIREQFKKKLEERLLSPHVPSAQLSGSRSRYKIKLRQAGYRLVYEVRDKQLIVLVVAVGK
RERNAAYKAAERR

Nucleotide

• Length: 282 bp

>T58169 NZ_CP013234:c5231730-5231449 [Collimonas pratensis]
ATGAACTTTGAGCTCGCGTTTCTTGAAGAAGCGTTGAAGGAATGGCGCAAGCTTGATCAGGGCATACGCGAGCAATTCAA
GAAAAAACTGGAAGAACGATTGTTGAGTCCGCATGTGCCATCGGCACAGCTTTCCGGCTCTCGCAGCCGCTATAAAATCA
AGCTGCGGCAGGCCGGTTATCGCCTGGTGTATGAAGTGCGCGACAAGCAACTGATCGTATTGGTGGTGGCCGTGGGCAAG
CGAGAGCGCAATGCCGCATACAAGGCTGCCGAAAGACGTTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 8834.25 Da
• Isoelectric Point: 4.7023

>AT58169 WP_061944852.1 NZ_CP013234:c5231968-5231720 [Collimonas pratensis]
MAHLILAETTASVSELKKDPMGTVAAGEGFPVAILNRNQPAFYCVPAKAYEALMNKLEDMELNAIADARSSQAVIKVKLD
EL

Nucleotide

• Length: 249 bp

>AT58169 NZ_CP013234:c5231968-5231720 [Collimonas pratensis]
ATGGCGCACCTAATTCTTGCCGAAACAACCGCCAGCGTTTCCGAGCTAAAGAAAGACCCTATGGGAACTGTCGCTGCCGG
CGAAGGATTTCCCGTGGCTATCTTGAACCGGAACCAGCCTGCCTTCTATTGCGTTCCGGCGAAGGCCTATGAAGCGCTGA
TGAACAAACTGGAAGACATGGAGCTGAATGCCATTGCGGATGCGCGCAGCAGCCAGGCGGTCATCAAGGTCAAGCTGGAT
GAACTTTGA

Structures

Toxin

• AlphaFold DB: A0A127QBH8