Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 3403935..3404615 Replicon chromosome
Accession NZ_CP013234
Organism Collimonas pratensis strain Ter91

Toxin (Protein)


Gene name vapC Uniprot ID A0A127Q6I1
Locus tag CPter91_RS15230 Protein ID WP_061941694.1
Coordinates 3403935..3404345 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A127QX09
Locus tag CPter91_RS15235 Protein ID WP_061941696.1
Coordinates 3404403..3404615 (-) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPter91_RS15215 3399144..3402089 - 2946 WP_061941690.1 DUF2135 domain-containing protein -
CPter91_RS15220 3402293..3402892 + 600 WP_061941691.1 sigma-70 family RNA polymerase sigma factor -
CPter91_RS15225 3402889..3403581 + 693 WP_150119714.1 hypothetical protein -
CPter91_RS26555 3403614..3403898 + 285 WP_150119715.1 hypothetical protein -
CPter91_RS15230 3403935..3404345 - 411 WP_061941694.1 type II toxin-antitoxin system VapC family toxin Toxin
CPter91_RS15235 3404403..3404615 - 213 WP_061941696.1 hypothetical protein Antitoxin
CPter91_RS15240 3404918..3405883 - 966 WP_061941697.1 NAD-dependent epimerase/dehydratase family protein -
CPter91_RS15245 3405906..3407141 - 1236 WP_061941699.1 glycine C-acetyltransferase -
CPter91_RS15250 3407299..3407880 + 582 WP_099047209.1 XRE family transcriptional regulator -
CPter91_RS15255 3407984..3408439 - 456 WP_061946288.1 glycine zipper 2TM domain-containing protein -
CPter91_RS15260 3408684..3409433 - 750 WP_061941701.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Uncharacterised conserved protein UCP008505

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15174.21 Da        Isoelectric Point: 4.8780

>T58167 WP_061941694.1 NZ_CP013234:c3404345-3403935 [Collimonas pratensis]
VYLLDTNVISESRKGAKANRGTQEFWRSVDLDAIYLPVQSIGEIRRGVEIVKRRGDSAQAKMLETWLQTLTTEYADRILS
FDDDCAQVWGCLMSADNQHPIDKQIAAIALIHSMTVVTRNTGDFIGTGVDLINPFS

Download         Length: 411 bp

>T58167 NZ_CP013234:c3404345-3403935 [Collimonas pratensis]
GTGTATCTGCTAGATACCAATGTCATCAGCGAGTCCCGTAAAGGGGCAAAAGCCAACCGCGGAACGCAGGAGTTCTGGCG
CTCGGTCGACCTCGATGCGATTTATCTGCCGGTGCAAAGCATAGGCGAAATACGCCGCGGCGTTGAAATCGTCAAGCGCC
GTGGCGATTCGGCGCAGGCCAAAATGCTGGAGACATGGCTGCAGACGCTGACCACGGAATATGCTGATCGTATCCTGTCG
TTTGACGACGACTGTGCCCAGGTGTGGGGGTGTCTGATGTCTGCCGACAATCAACATCCGATCGATAAGCAAATTGCCGC
GATCGCCTTGATCCATAGCATGACTGTCGTTACGCGTAATACCGGCGATTTTATCGGTACAGGCGTGGACCTGATAAATC
CATTTTCCTGA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 7884.93 Da        Isoelectric Point: 7.2049

>AT58167 WP_061941696.1 NZ_CP013234:c3404615-3404403 [Collimonas pratensis]
MATNLVVRNVEEELTLALKQQAAAHGRSAEAEHREILRAALQRPKRRSLVDFLLSMPNVGEDKDFDARNS

Download         Length: 213 bp

>AT58167 NZ_CP013234:c3404615-3404403 [Collimonas pratensis]
ATGGCTACAAACCTGGTGGTGAGAAACGTGGAAGAAGAACTTACTCTGGCACTCAAGCAACAGGCGGCGGCGCATGGCCG
CAGCGCAGAAGCCGAGCACAGGGAAATCCTGCGGGCGGCGCTACAGCGTCCGAAGCGGCGCTCGCTGGTGGACTTCTTGT
TGAGCATGCCGAATGTCGGGGAAGACAAGGACTTCGATGCGCGCAATAGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A127Q6I1

Antitoxin

Source ID Structure
AlphaFold DB A0A127QX09

References