Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1276032..1276699 Replicon chromosome
Accession NZ_CP013234
Organism Collimonas pratensis strain Ter91

Toxin (Protein)


Gene name vapC Uniprot ID A0A127Q0Q6
Locus tag CPter91_RS05760 Protein ID WP_061938144.1
Coordinates 1276283..1276699 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CPter91_RS05755 Protein ID WP_061938141.1
Coordinates 1276032..1276286 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPter91_RS05730 1271359..1272183 + 825 WP_061938130.1 carbon-nitrogen hydrolase family protein -
CPter91_RS05735 1272342..1273802 + 1461 WP_061938133.1 metalloprotease TldD -
CPter91_RS05740 1273823..1274290 + 468 WP_061945879.1 GNAT family N-acetyltransferase -
CPter91_RS05745 1274346..1274681 - 336 WP_061945881.1 glyoxalase -
CPter91_RS05750 1274912..1275934 + 1023 WP_061938138.1 cupin-like domain-containing protein -
CPter91_RS05755 1276032..1276286 + 255 WP_061938141.1 hypothetical protein Antitoxin
CPter91_RS05760 1276283..1276699 + 417 WP_061938144.1 type II toxin-antitoxin system VapC family toxin Toxin
CPter91_RS05765 1276765..1277136 + 372 WP_061938147.1 cupin domain-containing protein -
CPter91_RS05770 1277153..1277440 - 288 WP_061945883.1 metal-binding protein -
CPter91_RS05775 1277449..1278528 - 1080 WP_061938150.1 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada -
CPter91_RS05780 1278608..1279276 - 669 WP_061938153.1 DNA-3-methyladenine glycosylase -
CPter91_RS05785 1279276..1279929 - 654 WP_061938155.1 DNA oxidative demethylase AlkB -
CPter91_RS05790 1279939..1280679 - 741 WP_061938156.1 2OG-Fe(II) oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14768.92 Da        Isoelectric Point: 5.1224

>T58163 WP_061938144.1 NZ_CP013234:1276283-1276699 [Collimonas pratensis]
MIVLDTNVVSEAMKPEPHSAVRAWLNDQAAETLYLSSVTLAELLFGIGALPAGKRKDMLAQALDELGRLFRDRVLPFDSD
AAQHYADLAVKARAAGRGFPMPDGYIAAIAVSRGFIVASRDTAPFDAAGVSVINPWQA

Download         Length: 417 bp

>T58163 NZ_CP013234:1276283-1276699 [Collimonas pratensis]
ATGATTGTTCTCGATACCAATGTTGTTTCCGAGGCGATGAAACCGGAGCCGCATTCCGCCGTGCGGGCATGGCTGAACGA
TCAAGCCGCTGAAACGCTGTATCTGTCCAGCGTGACGCTGGCAGAGCTGCTGTTTGGCATCGGCGCGCTCCCTGCGGGCA
AGCGCAAAGACATGTTGGCACAGGCCCTTGACGAACTGGGGCGACTATTCAGGGATCGCGTGCTGCCATTCGACAGCGAT
GCAGCACAGCACTATGCTGACCTGGCCGTGAAGGCCAGGGCCGCCGGGCGAGGATTCCCGATGCCTGACGGTTACATAGC
TGCGATTGCAGTTTCGCGGGGATTCATCGTGGCATCACGCGACACGGCGCCTTTTGACGCCGCTGGCGTCAGCGTCATCA
ATCCTTGGCAGGCGTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9309.76 Da        Isoelectric Point: 5.7152

>AT58163 WP_061938141.1 NZ_CP013234:1276032-1276286 [Collimonas pratensis]
MAMLTVRNLPDEVHRALRVRAAQHGRSTEAEVREILAIAVKPETRVLIGEALAALGQKIGLTNEDVEVLEQLTEKTPAQP
LRFE

Download         Length: 255 bp

>AT58163 NZ_CP013234:1276032-1276286 [Collimonas pratensis]
ATGGCAATGTTGACAGTACGCAATTTGCCCGACGAGGTGCATCGCGCACTGCGGGTACGGGCCGCTCAACATGGCCGCAG
CACCGAGGCCGAAGTCCGCGAGATTCTGGCGATCGCAGTCAAACCAGAGACCCGAGTTCTGATTGGTGAAGCCCTGGCGG
CATTGGGCCAGAAGATCGGTCTCACGAATGAGGATGTCGAGGTTCTCGAACAATTGACAGAGAAGACTCCGGCCCAGCCG
TTGAGGTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A127Q0Q6

Antitoxin

Source ID Structure

References