Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 5197568..5198087 Replicon chromosome
Accession NZ_CP013232
Organism Collimonas fungivorans strain Ter6

Toxin (Protein)


Gene name relE Uniprot ID A0A127PIH3
Locus tag CFter6_RS22795 Protein ID WP_061541840.1
Coordinates 5197568..5197849 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A127PIC5
Locus tag CFter6_RS22800 Protein ID WP_061542534.1
Coordinates 5197839..5198087 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFter6_RS22780 5193492..5195285 + 1794 WP_082814947.1 FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC -
CFter6_RS22785 5195329..5195646 - 318 WP_061541838.1 YXWGXW repeat-containing protein -
CFter6_RS22790 5195902..5197533 + 1632 WP_061541839.1 NAD(P)/FAD-dependent oxidoreductase -
CFter6_RS22795 5197568..5197849 - 282 WP_061541840.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFter6_RS22800 5197839..5198087 - 249 WP_061542534.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CFter6_RS22805 5198331..5198693 - 363 WP_061542535.1 hypothetical protein -
CFter6_RS22810 5198827..5199396 + 570 WP_014008055.1 MASE1 domain-containing protein -
CFter6_RS22815 5199537..5199944 + 408 WP_014008056.1 biopolymer transporter ExbD -
CFter6_RS22820 5199953..5200672 + 720 WP_061542536.1 TonB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10973.80 Da        Isoelectric Point: 10.7271

>T58160 WP_061541840.1 NZ_CP013232:c5197849-5197568 [Collimonas fungivorans]
MSFELAFLEEALKEWRKLDQGMREQFKKKLAERLHTPHVPSAQLSGSRSRYKIKLRQAGYRLVYEVRDQELIVLVVAVGK
RERNAVYKAAEKR

Download         Length: 282 bp

>T58160 NZ_CP013232:c5197849-5197568 [Collimonas fungivorans]
ATGAGCTTTGAACTGGCTTTCCTTGAGGAAGCATTGAAGGAATGGCGCAAGCTGGATCAAGGCATGCGCGAGCAGTTCAA
AAAGAAACTGGCGGAACGATTGCATACTCCTCATGTTCCATCCGCACAGTTATCCGGCTCCAGAAGCCGATATAAAATCA
AGCTGCGCCAGGCCGGCTACCGGCTAGTCTACGAAGTGCGTGACCAGGAGTTGATCGTGCTGGTCGTCGCCGTAGGCAAG
CGCGAGCGTAACGCAGTGTACAAGGCTGCGGAAAAACGTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8888.30 Da        Isoelectric Point: 4.5338

>AT58160 WP_061542534.1 NZ_CP013232:c5198087-5197839 [Collimonas fungivorans]
MAHLILAETTASVSELKKDPMGTVAAGEGFPVVILNRNQPAFYCVPAKAYEALMNKLEDMELNAVADAREGQAVIRVKLD
EL

Download         Length: 249 bp

>AT58160 NZ_CP013232:c5198087-5197839 [Collimonas fungivorans]
ATGGCACACCTGATTCTTGCCGAAACAACCGCCAGCGTTTCCGAGTTGAAAAAAGACCCTATGGGAACTGTTGCTGCAGG
TGAAGGATTTCCTGTAGTGATATTGAACCGGAACCAGCCAGCTTTTTATTGTGTCCCGGCAAAAGCCTATGAAGCGCTGA
TGAACAAGCTGGAAGACATGGAGCTGAATGCCGTTGCAGACGCCCGCGAAGGGCAAGCTGTTATCAGGGTCAAGCTGGAT
GAGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A127PIH3

Antitoxin

Source ID Structure
AlphaFold DB A0A127PIC5

References