Detailed information of TA system TA058157

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): AbkB-shpB/BrnT-BrnA
• Location: 4328458..4329010
• Replicon: chromosome
• Accession: NZ_CP013232
• Organism: Collimonas fungivorans strain Ter6

Toxin (Protein)

• Gene name: AbkB
• Uniprot ID: -
• Locus tag: CFter6_RS18885
• Protein ID: WP_061541225.1
• Coordinates: 4328458..4328754 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: shpB
• Uniprot ID: A0A127PG59
• Locus tag: CFter6_RS18890
• Protein ID: WP_061541226.1
• Coordinates: 4328738..4329010 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CFter6_RS18870	4324729..4326006	-	1278	WP_061542468.1	SGNH/GDSL hydrolase family protein	-
CFter6_RS18875	4326400..4327056	+	657	WP_061541224.1	response regulator transcription factor	-
CFter6_RS18880	4327053..4328374	+	1322	Protein_3821	two-component sensor histidine kinase	-
CFter6_RS18885	4328458..4328754	+	297	WP_061541225.1	BrnT family toxin	Toxin
CFter6_RS18890	4328738..4329010	+	273	WP_061541226.1	BrnA antitoxin family protein	Antitoxin
CFter6_RS18895	4329116..4330597	+	1482	WP_061541227.1	DegQ family serine endoprotease	-
CFter6_RS18900	4330623..4330925	+	303	WP_061541228.1	hypothetical protein	-
CFter6_RS18905	4331370..4331795	+	426	WP_061541229.1	YciI family protein	-
CFter6_RS18910	4331832..4332356	+	525	WP_061541230.1	SRPBCC family protein	-
CFter6_RS18915	4332438..4332848	+	411	WP_061541231.1	glyoxalase/bleomycin resistance/extradiol dioxygenase family protein	-
CFter6_RS18920	4332906..4333133	-	228	WP_061541232.1	hypothetical protein	-
CFter6_RS18925	4333194..4333670	-	477	WP_061541233.1	Lrp/AsnC family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (8-90)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (27-83)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11494.81 Da
• Isoelectric Point: 6.2182

>T58157 WP_061541225.1 NZ_CP013232:4328458-4328754 [Collimonas fungivorans]
MELQLFSWDDEKNESNQRKHGLNFEAATHVFDDPLHITRQDRVENNEQRWQTIGMVSGVILLLVAHTWHEAESGSEHIRI
ISARRATKLERKIYEQGT

Nucleotide

• Length: 297 bp

>T58157 NZ_CP013232:4328458-4328754 [Collimonas fungivorans]
TTGGAGTTACAATTGTTTTCATGGGATGATGAAAAAAACGAGAGTAACCAGCGCAAACATGGCCTCAATTTTGAGGCCGC
GACACATGTCTTTGACGACCCTTTGCATATCACCAGGCAAGATCGCGTCGAAAACAACGAACAGCGATGGCAGACCATCG
GCATGGTCAGCGGCGTCATCTTGTTGTTGGTTGCCCATACCTGGCATGAAGCAGAAAGCGGCTCAGAACATATTCGCATC
ATCTCGGCGCGGCGCGCGACAAAACTGGAAAGGAAAATCTATGAGCAAGGTACCTGA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10256.80 Da
• Isoelectric Point: 10.2089

>AT58157 WP_061541226.1 NZ_CP013232:4328738-4329010 [Collimonas fungivorans]
MSKVPESIRKELAALAAKPESDIDFSDLPATTKQDWQGAVRGKFYRPVKQQLTVRIDADVVGWLKEEGKGYQSRMNDILR
AAMLDKVRHR

Nucleotide

• Length: 273 bp

>AT58157 NZ_CP013232:4328738-4329010 [Collimonas fungivorans]
ATGAGCAAGGTACCTGAATCTATCCGCAAGGAACTGGCAGCATTGGCCGCCAAACCAGAGAGCGATATCGATTTCTCCGA
CCTCCCCGCCACCACCAAACAGGATTGGCAAGGCGCAGTCCGCGGGAAATTCTATCGCCCTGTCAAACAGCAGTTGACGG
TACGCATTGATGCCGATGTCGTGGGGTGGCTCAAGGAAGAAGGAAAAGGTTACCAAAGCCGCATGAACGATATCTTGCGG
GCAGCCATGCTGGACAAGGTTCGCCACCGGTGA

Structures

Antitoxin

• AlphaFold DB: A0A127PG59